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Xin Chen
Xin Chen
BeiGene USA, Inc
Verified email at tsinghua.edu.cn
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Year
Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility
H Xu, X Li, D Liu, J Li, X Zhang, X Chen, S Hou, L Peng, C Xu, W Liu, ...
Nature 496 (7446), 523-527, 2013
4462013
Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development
X Liu, X Chen, B Zhong, A Wang, X Wang, F Chu, RI Nurieva, X Yan, ...
Nature 507 (7493), 513-518, 2014
3592014
FcγR-binding is an important functional attribute for immune checkpoint antibodies in cancer immunotherapy
X Chen, X Song, K Li, T Zhang
Frontiers in immunology 10, 439909, 2019
1422019
An efficient one‐pot four‐segment condensation method for protein chemical synthesis
S Tang, YY Si, ZP Wang, KR Mei, X Chen, JY Cheng, JS Zheng, L Liu
Angewandte Chemie International Edition 54 (19), 5713-5717, 2015
1412015
A GPR174–CCL21 module imparts sexual dimorphism to humoral immunity
R Zhao, X Chen, W Ma, J Zhang, J Guo, X Zhong, J Yao, J Sun, ...
Nature 577 (7790), 416-420, 2020
752020
Phenotypic Tfh development promoted by CXCR5-controlled re-localization and IL-6 from radiation-resistant cells
X Chen, W Ma, T Zhang, L Wu, H Qi
Protein & cell 6 (11), 825-832, 2015
492015
Chemical synthesis of a two-photon-activatable chemokine and photon-guided lymphocyte migration in vivo
X Chen, S Tang, JS Zheng, R Zhao, ZP Wang, W Shao, HN Chang, ...
Nature communications 6 (1), 7220, 2015
432015
Neuronal, stromal, and T-regulatory cell crosstalk in murine skeletal muscle
K Wang, OK Yaghi, RG Spallanzani, X Chen, D Zemmour, N Lai, IM Chiu, ...
Proceedings of the National Academy of Sciences 117 (10), 5402-5408, 2020
362020
Follicular T‐helper cells: controlled localization and cellular interactions
H Qi, X Chen, C Chu, P Lu, H Xu, J Yan
Immunology and Cell Biology 92 (1), 28-33, 2014
362014
Total chemical synthesis of photoactivatable proteins for light-controlled manipulation of antigen–antibody interactions
S Tang, Z Wan, Y Gao, JS Zheng, J Wang, YY Si, X Chen, H Qi, L Liu, ...
Chemical Science 7 (3), 1891-1895, 2016
302016
An Fc-competent anti-human TIGIT blocking antibody ociperlimab (BGB-A1217) elicits strong immune responses and potent anti-tumor efficacy in pre-clinical models
X Chen, L Xue, X Ding, J Zhang, L Jiang, S Liu, H Hou, B Jiang, L Cheng, ...
Frontiers in Immunology 13, 828319, 2022
262022
A new method for synthesis of peptide thioesters via irreversible N-to-S acyl transfer
JS Zheng, X Chen, S Tang, HN Chang, FL Wang, C Zuo
Organic letters 16 (18), 4908-4911, 2014
212014
Tfh cell differentiation and their function in promoting B-cell responses
H Qi, X Chen, C Chu, D Liu, W Ma, Y Wang, L Wu, H Yan, J Yan
T Helper Cell Differentiation and Their Function, 153-180, 2014
202014
Nuclear receptors of the NR4a family are not required for the development and function of follicular T helper cells
W Ma, R Zhao, R Yang, B Liu, X Chen, L Wu, H Qi
International immunopharmacology 28 (2), 841-845, 2015
92015
A new and robust method of tethering IgG surrogate antigens on lipid bilayer membranes to facilitate the TIRFM based live cell and single molecule imaging experiments
S Zhang, L Xu, X Zhao, X Chen, Y Fan, Z Wan, Y Xu, W Liu
PloS one 8 (5), e63735, 2013
72013
Natural killer cells: the next wave in cancer immunotherapy
X Chen, L Jiang, X Liu
Frontiers in immunology 13, 954804, 2022
62022
A Fc-competent anti-human TIGIT blocking antibody BGB-A1217 elicits strong immune responses and potent anti-tumor efficacy in pre-clinical models
X Chen, L Xue, X Ding, Q Liu, J Zhang, L Jiang, S Liu, H Hou, Q Zhu, ...
J Cancer Res 81 (suppl 13), 1854, 2021
62021
Deciphering the microbiome-immunity-cancer axis
X Chen, C Jin, A Facciabene, X Guo, Y Zhang
Frontiers in Immunology 13, 897811, 2022
22022
BGB-A445, a novel non-ligand-blocking agonistic anti-OX40 antibody, exhibits superior immune activation and antitumor effects in preclinical models
B Jiang, T Zhang, M Deng, W Jin, Y Hong, X Chen, X Chen, J Wang, ...
Frontiers of Medicine, 1-16, 2023
2023
Structural Insights into the Unique pH-Responsive Characteristics of the Anti-TIGIT Therapeutic Antibody Ociperlimab
J Sun, X Zhang, L Xue, L Cheng, J Zhang, X Chen, Z Shen, K Li, L Wang, ...
Available at SSRN 4575346, 0
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