Reduced growth rate of aged muscle stem cells is associated with impaired mechanosensitivity M Haroon, HE Boers, AD Bakker, NGC Bloks, WMH Hoogaars, L Giordani, ... Aging (Albany NY) 14 (1), 28, 2022 | 11 | 2022 |
A human in vitro 3D neo-cartilage model to explore the response of OA risk genes to hyper-physiological mechanical stress RGM Timmermans, NGC Bloks, M Tuerlings, M van Hoolwerff, ... Osteoarthritis and Cartilage Open 4 (1), 100231, 2022 | 10 | 2022 |
Fluid shear stress-induced mechanotransduction in myoblasts: Does it depend on the glycocalyx? M Haroon, NGC Bloks, L Deldicque, K Koppo, H Seddiqi, AD Bakker, ... Experimental cell research 417 (1), 113204, 2022 | 3 | 2022 |
A disease-risk mutation in COL6A3 alters the biologic response of chondrocytes to hyper-physiologic mechanical loading NG Bloks, A Dicks, SS Adkar, RG Timmermans, G Hajmousa, YF Ramos, ... Osteoarthritis and Cartilage 29, S123-S124, 2021 | 1 | 2021 |
Hyper-physiologic mechanical cues, as an osteoarthritis disease-relevant environmental perturbation, cause a critical shift in set points of methylation at transcriptionally … NGC Bloks, A Dicks, Z Harissa, RGHH Nelissen, G Hajmousa, ... Clinical Epigenetics 16 (1), 1-11, 2024 | | 2024 |
The role of DNA methylation in chondrogenesis of human iPSCs as a stable marker of cartilage quality G Hajmousa, RC de Almeida, N Bloks, AR Ruiz, M Bouma, R Slieker, ... | | 2023 |
CCN4/WISP1 Promotes Migration of Human Primary Osteoarthritic Chondrocytes RGM Timmermans, AB Blom, NGC Bloks, RGHH Nelissen, ... Cartilage 14 (1), 67-75, 2023 | | 2023 |
Hyper-Physiologic Mechanical Loading Conditions Cause A Shift In The Epigenetic Landscape In Neo-Cartilage Organoids N Bloks, Z Harissa, A Dicks, RC de Almeida, G Hajmousa, S Adkar, ... Osteoarthritis and Cartilage 31, S329-S330, 2023 | | 2023 |
A high-impact COL6A3 mutation alters the response of chondrocytes in neo-cartilage organoids to hyper-physiologic mechanical loading NGC Bloks, Z Harissa, SS Adkar, AR Dicks, G Hajmousa, N Steward, ... bioRxiv, 2022.12. 19.520461, 2022 | | 2022 |
OPPOSITE EFFECTS OF HYPER-PHYSIOLOGICAL MECHANICAL STRESS AND INFLAMMATION ON WNT SIGNALING IN HUMAN CHONDROCYTE NEO-CARTILAGE PELLETS RG Timmermans, NG Bloks, PL van Lent, PM van der Kraan, RG Nelissen, ... Osteoarthritis and Cartilage 30, S165-S166, 2022 | | 2022 |
Mechanical stress induces ADAMTS5 mediated cartilage damage in human neo-cartilage and activates non-canonical Wnt signaling and transcription factor FOS RG Timmermans, NG Bloks, MH van den Bosch, RG Nelissen, AB Blom, ... Osteoarthritis and Cartilage 29, S120-S121, 2021 | | 2021 |