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Mengqian Chen
Mengqian Chen
University of South Carolina, South Carolina College of Pharmacy
Verified email at sccp.sc.edu
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Cited by
Year
Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities
DC Porter, E Farmaki, S Altilia, GP Schools, DK West, M Chen, BD Chang, ...
Proceedings of the National Academy of Sciences 109 (34), 13799-13804, 2012
2092012
Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer
MSJ McDermott, AA Chumanevich, C Lim, J Liang, M Chen, S Altilia, ...
Oncotarget 8 (8), 12558, 2017
1232017
CDK8/19 Mediator kinases potentiate induction of transcription by NFκB
M Chen, J Liang, H Ji, Z Yang, S Altilia, B Hu, A Schronce, ...
Proceedings of the National Academy of Sciences 114 (38), 10208-10213, 2017
1192017
Expression of CDK8 and CDK8-interacting genes as potential biomarkers in breast cancer
E V Broude, B Gyorffy, A A Chumanevich, M Chen, M SJ McDermott, ...
Current cancer drug targets 15 (8), 739-749, 2015
952015
Androgenic regulation of hedgehog signaling pathway components in prostate cancer cells
M Chen, M Tanner, AC Levine, E Levina, P Ohouo, R Buttyan
Cell cycle (Georgetown, Tex.) 8 (1), 149, 2009
862009
CDK8 selectively promotes the growth of colon cancer metastases in the liver by regulating gene expression of TIMP3 and matrix metalloproteinases
J Liang, M Chen, D Hughes, AA Chumanevich, S Altilia, V Kaza, CU Lim, ...
Cancer research 78 (23), 6594-6606, 2018
822018
Editorial Comment on: Hedgehog Signalling in Androgen Independent Prostate Cancer
M Chen, R Buttyan
European Urology 54 (6), 1341-1343, 2008
80*2008
Hedgehog/Gli supports androgen signaling in androgen deprived and androgen independent prostate cancer cells
M Chen, MA Feuerstein, E Levina, PS Baghel, RD Carkner, MJ Tanner, ...
Molecular cancer 9, 1-12, 2010
752010
The epidermal growth factor receptor (EGFR) is proteolytically modified by the Matriptase-Prostasin serine protease cascade in cultured epithelial cells
M Chen, LM Chen, CY Lin, KX Chai
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (5), 896-903, 2008
722008
Therapy-induced developmental reprogramming of prostate cancer cells and acquired therapy resistance
M Nouri, J Caradec, AA Lubik, N Li, BG Hollier, M Takhar, ...
Oncotarget 8 (12), 18949, 2017
702017
Effects of androgen receptor and androgen on gene expression in prostate stromal fibroblasts and paracrine signaling to prostate cancer cells
MJ Tanner, RC Welliver, M Chen, M Shtutman, A Godoy, G Smith, ...
PloS one 6 (1), e16027, 2011
672011
The hedgehog/Gli signaling paradigm in prostate cancer
M Chen, R Carkner, R Buttyan
Expert review of endocrinology & metabolism 6 (3), 453, 2011
572011
Gli2 expression and human bladder transitional carcinoma cell invasiveness
CW Mechlin, MJ Tanner, M Chen, R Buttyan, RM Levin, BM Mian
The Journal of urology 184 (1), 344-351, 2010
572010
Hepsin activates prostasin and cleaves the extracellular domain of the epidermal growth factor receptor
M Chen, LM Chen, CY Lin, KX Chai
Molecular and cellular biochemistry 337 (1), 259-266, 2010
512010
The stress response mediator ATF3 represses androgen signaling by binding the androgen receptor
H Wang, M Jiang, H Cui, M Chen, R Buttyan, SW Hayward, T Hai, Z Wang, ...
Molecular and cellular biology, 2012
492012
Prostasin induces protease-dependent and independent molecular changes in the human prostate carcinoma cell line PC-3
M Chen, YY Fu, CY Lin, LM Chen, KX Chai
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1773 (7), 1133-1140, 2007
432007
Prostasin attenuates inducible nitric oxide synthase expression in lipopolysaccharide-induced urinary bladder inflammation
LM Chen, C Wang, M Chen, MR Marcello, J Chao, L Chao, KX Chai
American Journal of Physiology-Renal Physiology 291 (3), F567-F577, 2006
392006
Androgen regulation of prostasin gene expression is mediated by sterol‐regulatory element‐binding proteins and SLUG
M Chen, LM Chen, KX Chai
The Prostate 66 (9), 911-920, 2006
392006
Identification of novel cancer therapeutic targets using a designed and pooled shRNA library screen
D Oliver, H Ji, P Liu, A Gasparian, E Gardiner, S Lee, A Zenteno, ...
Scientific reports 7 (1), 43023, 2017
382017
Systemic toxicity reported for CDK8/19 inhibitors CCT251921 and MSC2530818 is not due to target inhibition
M Chen, J Li, J Liang, ZS Thompson, K Kathrein, EV Broude, IB Roninson
Cells 8 (11), 1413, 2019
372019
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