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Linda Schellhammer
Linda Schellhammer
University of Zurich
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Year
Enzymatic dissociation induces transcriptional and proteotype bias in brain cell populations
D Mattei, A Ivanov, M van Oostrum, S Pantelyushin, J Richetto, F Mueller, ...
International journal of molecular sciences 21 (21), 7944, 2020
992020
Delivery of antibodies into the murine brain via convection-enhanced delivery
M Beffinger, L Schellhammer, S Pantelyushin, J Vom Berg
JoVE (Journal of Visualized Experiments), e59675, 2019
82019
Early reduction of SARS-CoV-2-replication in bronchial epithelium by kinin B2 receptor antagonism
CA Jakwerth, M Feuerherd, FM Guerth, M Oelsner, L Schellhammer, ...
Journal of Molecular Medicine, 1-15, 2022
62022
Exit pathways of therapeutic antibodies from the brain and retention strategies
L Schellhammer, M Beffinger, U Salazar, JD Laman, T Buch, J Vom Berg
Iscience, 2023
2023
Fc-modified biologicals for local delivery to compartments, in particular to the cns
J Vom Berg, D Morger, L Schellhammer, M Beffinger, T Buch
US Patent App. 17/599,856, 2022
2022
Fc-MODIFIED BIOLOGICALS FOR LOCAL DELIVERY TO COMPARTMENT, IN PARTICULAR TO THE CNS
J Vom Berg, D Morger, L Schellhammer, M Beffinger, T Buch
US Patent App. 17/599,921, 2022
2022
Development of a compartment locked IL-12 version with increased tissue retention and minimal peripheral exposure for local glioblastoma therapy
L Schellhammer, M Beffinger, S Deplazes, T Shekarian, I Zimmermann, ...
Brain Tumor Research and Treatment 10 (Suppl), 2022
2022
DDRE-48. COMPARTMENT LOCKED IL-12-INCREASED TISSUE RETENTION AND MINIMAL PERIPHERAL EXPOSURE ALLOW HIGHER TREATMENT EFFICACY AND TOLERABILITY IN LOCAL GLIOBLASTOMA THERAPY
M Beffinger, L Schellhammer, T Shekarian, S Deplazes, I Zimmermann, ...
Neuro-Oncology 23 (Supplement_6), vi85-vi85, 2021
2021
Early Reduction of SARS-CoV-2 Replication in Bronchial Epithelium by Kinin B2 Receptor Antagonism (preprint)
C Jakwerth, M Feuerherd, F Guerth, M Oelsner, L Schellhammer, ...
2021
P09. 10 Local immunotherapy of brain cancer harnessing high-retention Fc-fusion constructs
L Schellhammer, M Beffinger, S Pantelyushin, T Buch, J vom Berg
Journal for ImmunoTherapy of Cancer 8 (Suppl 2), 2020
2020
SCIDOT-06. TOWARDS EXCLUSIVELY LOCAL THERAPY OF GLIOBLASTOMA-ENGINEERING IL-12Fc WITH SUPERIOR TISSUE RETENTION AND MINIMAL SYSTEMIC EXPOSURE AFTER CNS ADMINISTRATION
M Beffinger, L Schellhammer, S Pantelyushin, I Zimmermann, P Egloff, ...
Neuro-Oncology 21 (Suppl 6), vi273, 2019
2019
Towards exclusively local therapy of glioblastoma-Engineering IL-12Fc with superior tissue retention and minimal systemic exposure after CNS administration
L Schellhammer, M Beffinger, S Pantelyushin, I Zimmermann, P Egloff, ...
EUROPEAN JOURNAL OF IMMUNOLOGY 49, 228-229, 2019
2019
SCDT-41. IN VIVO TESTING OF INTRACRANIAL DELIVERY OF RECOMBINANT HUMAN IL-12 AND IL-12Fc AND FUNCTIONAL ASSESSMENT ON HUMAN, PORCINE AND CANINE PERIPHERAL BLOOD MONONUCLEAR CELLS
M Beffinger, L Schellhammer, S Pantelyushin, SK Wall, A Bienemann, ...
Neuro-Oncology 19 (Suppl 6), vi273, 2017
2017
P06. 09 In vitro assessment of human IL-12Fc function on porcine and canine peripheral blood mononuclear cells
L Schellhammer, M Beffinger, A Parshenkov, B Becher, A Bienemann, ...
Neuro-Oncology 19 (Suppl 3), iii51, 2017
2017
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