| Bioprocess digital twins of mammalian cell culture for advanced biomanufacturing SY Park, CH Park, DH Choi, JK Hong, DY Lee Current Opinion in Chemical Engineering 33, 100702, 2021 | 42 | 2021 |
| Linking process variables to residence time distribution in a hybrid flowsheet model for continuous direct compression SC Galbraith, S Park, Z Huang, H Liu, RF Meyer, M Metzger, MH Flamm, ... Chemical Engineering Research and Design 153, 85-95, 2020 | 28 | 2020 |
| Prediction of critical quality attributes and optimization of continuous dry granulation process via flowsheet modeling and experimental validation SY Park, SC Galbraith, H Liu, HW Lee, B Cha, Z Huang, T O'Connor, ... Powder technology 330, 461-470, 2018 | 28 | 2018 |
| Integrated modeling of a continuous direct compression tablet manufacturing process: a production scale case study SC Galbraith, B Cha, Z Huang, S Park, H Liu, RF Meyer, MH Flamm, ... Powder technology 354, 199-210, 2019 | 27 | 2019 |
| Modeling and simulation of continuous powder blending applied to a continuous direct compression process SC Galbraith, H Liu, B Cha, SY Park, Z Huang, S Yoon Pharmaceutical Development and Technology 23 (10), 1097-1107, 2018 | 21 | 2018 |
| Assessment of spatial heterogeneity in continuous twin screw wet granulation process using three-compartmental population balance model H Liu, SC Galbraith, SY Park, B Cha, Z Huang, RF Meyer, MH Flamm, ... Pharmaceutical development and technology 24 (1), 105-117, 2019 | 18 | 2019 |
| Bigdata analytics identifies metabolic inhibitors and promoters for productivity improvement and optimization of monoclonal antibody (mAb) production process C Morris, A Polanco, A Yongky, J Xu, Z Huang, J Zhao, KS McFarland, ... Bioresources and Bioprocessing 7, 1-13, 2020 | 14 | 2020 |
| Metabolic responses and pathway changes of mammalian cells under different culture conditions with media supplementations SY Park, TM Reimonn, CD Agarabi, KA Brorson, S Yoon Biotechnology Progress 34 (3), 793-805, 2018 | 13 | 2018 |
| Data-driven and model-guided systematic framework for media development in CHO cell culture JK Hong, DH Choi, SY Park, YR Silberberg, F Shozui, E Nakamura, ... Metabolic Engineering 73, 114-123, 2022 | 12 | 2022 |
| Emerging computational tools and models for studying gut microbiota composition and function SY Park, A Ufondu, K Lee, A Jayaraman Current opinion in biotechnology 66, 301-311, 2020 | 11 | 2020 |
| Effect of amino acid supplementation on titer and glycosylation distribution in hybridoma cell cultures—Systems biology‐based interpretation using genome‐scale metabolic flux … TM Reimonn, SY Park, CD Agarabi, KA Brorson, S Yoon Biotechnology Progress 32 (5), 1163-1173, 2016 | 11 | 2016 |
| A new cloning strategy for generating multiple repeats of a repetitive polypeptide based on non-template PCR HS Chu, J Ryum, SY Park, BG Kim, DM Kim, JI Won Biotechnology letters 33, 977-983, 2011 | 11 | 2011 |
| Combined multivariate statistical and flux balance analyses uncover media bottlenecks to the growth and productivity of Chinese hamster ovary cell cultures HC Yeo, SY Park, T Tan, SK Ng, M Lakshmanan, DY Lee Biotechnology and Bioengineering 119 (7), 1740-1754, 2022 | 10 | 2022 |
| Increased 2,3‐butanediol production by changing codon usages in Escherichia coli SY Park, B Kim, S Lee, M Oh, JI Won, J Lee Biotechnology and Applied Biochemistry 61 (5), 535-540, 2014 | 10 | 2014 |
| An analysis of the concentration change of intermediate metabolites by gene manipulation in fatty acid biosynthesis SY Park, E Jeon, S Lee, J Lee, T Lee, JI Won Enzyme and microbial technology 51 (2), 95-99, 2012 | 10 | 2012 |
| Data‐driven prediction models for forecasting multistep ahead profiles of mammalian cell culture toward bioprocess digital twins SY Park, SJ Kim, CH Park, J Kim, DY Lee Biotechnology and Bioengineering 120 (9), 2494-2508, 2023 | 8 | 2023 |
| A thermodynamic balance model for liquid film drying kinetics of a tablet film coating and drying process B Cha, SC Galbraith, H Liu, SY Park, Z Huang, T O’Connor, S Lee, ... AAPS PharmSciTech 20, 1-13, 2019 | 8 | 2019 |
| Development of a three-compartmental population balance model for a continuous twin screw wet granulation process H Liu, SC Galbraith, SY Park, B Cha, Z Huang, RF Meyer, MH Flamm, ... Pharm. Dev. Technol 7450, 1-39, 2018 | 8 | 2018 |
| Untargeted proteomics reveals upregulation of stress response pathways during CHO-based monoclonal antibody manufacturing process leading to disulfide bond reduction SY Park, S Egan, AJ Cura, KL Aron, X Xu, M Zheng, M Borys, S Ghose, ... Mabs 13 (1), 1963094, 2021 | 5 | 2021 |
| Effects of process parameters on tablet critical quality attributes in continuous direct compression: a case study of integrating data-driven statistical models and mechanistic … Z Huang, SC Galbraith, B Cha, H Liu, S Park, MH Flamm, M Metzger, ... Pharmaceutical Development and Technology 25 (10), 1204-1215, 2020 | 5 | 2020 |
