Sense codon reassignment enables viral resistance and encoded polymer synthesis WE Robertson, LFH Funke, D de la Torre, J Fredens, TS Elliott, M Spinck, ... Science 372 (6546), 1057-1062, 2021 | 141 | 2021 |
Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution M Gao, J Wang, S Rousseaux, M Tan, L Pan, L Peng, S Wang, W Xu, ... Cell Reports 36 (4), 2021 | 38 | 2021 |
Genetically programmed cell-based synthesis of non-natural peptide and depsipeptide macrocycles M Spinck, C Piedrafita, WE Robertson, TS Elliott, D Cervettini, ... Nature chemistry 15 (1), 61-69, 2023 | 30 | 2023 |
Evolved, selective erasers of distinct lysine acylations M Spinck, P Neumann‐Staubitz, M Ecke, R Gasper, H Neumann Angewandte Chemie International Edition 59 (27), 11142-11149, 2020 | 25 | 2020 |
Continuous synthesis of E. coli genome sections and Mb-scale human DNA assembly JF Zürcher, AA Kleefeldt, LFH Funke, J Birnbaum, J Fredens, S Grazioli, ... Nature 619 (7970), 555-562, 2023 | 22 | 2023 |
Discovery of dihydro-1, 4-benzoxazine carboxamides as potent and highly selective inhibitors of sirtuin-1 M Spinck, M Bischoff, P Lampe, FJ Meyer-Almes, S Sievers, H Neumann Journal of Medicinal Chemistry 64 (9), 5838-5849, 2021 | 18 | 2021 |
Highly sensitive lysine deacetylase assay based on acetylated firefly luciferase M Spinck, M Ecke, S Sievers, H Neumann Biochemistry 57 (26), 3552-3555, 2018 | 13 | 2018 |
Evolvierte, selektive Eraser für spezifische Lysinacylierungen M Spinck, P Neumann‐Staubitz, M Ecke, R Gasper, H Neumann Angewandte Chemie 132 (27), 11236-11243, 2020 | 3 | 2020 |
A directed evolution system for lysine deacetylases M Spinck, M Ecke, D Schiller, H Neumann Multiprotein Complexes: Methods and Protocols, 319-337, 2021 | 2 | 2021 |
Laboratory-Scale Hydroxylation of Steroids by P450BM3 Variants S Hoebenreich, M Spinck, N Nett Microbial Steroids: Methods and Protocols, 239-257, 2017 | 2 | 2017 |
Kdac variants and uses thereof H Neumann, M Spinck US Patent App. 16/647,852, 2020 | | 2020 |
Directed evolution of lysine deacetylases M Spinck Dissertation, Dortmund, Technische Universität, 2020, 2020 | | 2020 |