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John Le Quesne
John Le Quesne
Verified email at glasgow.ac.uk
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Tracking the evolution of non–small-cell lung cancer
M Jamal-Hanjani, GA Wilson, N McGranahan, NJ Birkbak, TBK Watkins, ...
New England Journal of Medicine 376 (22), 2109-2121, 2017
21442017
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ...
Nature 545 (7655), 446-451, 2017
16562017
Allele-specific HLA loss and immune escape in lung cancer evolution
N McGranahan, R Rosenthal, CT Hiley, AJ Rowan, TBK Watkins, ...
Cell 171 (6), 1259-1271. e11, 2017
11392017
Fc effector function contributes to the activity of human anti-CTLA-4 antibodies
FA Vargas, AJS Furness, K Litchfield, K Joshi, R Rosenthal, E Ghorani, ...
Cancer cell 33 (4), 649-663. e4, 2018
5312018
C-Myc 5′ untranslated region contains an internal ribosome entry segment
M Stoneley, FEM Paulin, JPC Le Quesne, SA Chappell, AE Willis
Oncogene 16 (3), 423-428, 1998
4331998
Fc-optimized anti-CD25 depletes tumor-infiltrating regulatory T cells and synergizes with PD-1 blockade to eradicate established tumors
FA Vargas, AJS Furness, I Solomon, K Joshi, L Mekkaoui, MH Lesko, ...
Immunity 46 (4), 577-586, 2017
4092017
BCL2 in breast cancer: a favourable prognostic marker across molecular subtypes and independent of adjuvant therapy received
SJ Dawson, N Makretsov, FM Blows, KE Driver, E Provenzano, ...
British journal of cancer 103 (5), 668-675, 2010
3652010
Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity
M Halliday, H Radford, Y Sekine, J Moreno, N Verity, J Le Quesne, ...
Cell death & disease 6 (3), e1672-e1672, 2015
3322015
Tracking genomic cancer evolution for precision medicine: the lung TRACERx study
M Jamal-Hanjani, A Hackshaw, Y Ngai, J Shaw, C Dive, S Quezada, ...
PLoS biology 12 (7), e1001906, 2014
2972014
Analysis of the c-myc IRES; a potential role for cell-type specific trans-acting factors and the nuclear compartment
M Stoneley, T Subkhankulova, JPC Le Quesne, MJ Coldwell, CL Jopling, ...
Nucleic acids research 28 (3), 687-694, 2000
2532000
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma
K AbdulJabbar, SEA Raza, R Rosenthal, M Jamal-Hanjani, S Veeriah, ...
Nature medicine 26 (7), 1054-1062, 2020
2232020
Micro-RNAs and breast cancer
J Le Quesne, C Caldas
Molecular oncology 4 (3), 230-241, 2010
1962010
The path to a better biomarker: application of a risk management framework for the implementation of PD‐L1 and TILs as immuno‐oncology biomarkers in breast cancer clinical …
PI Gonzalez‐Ericsson, ES Stovgaard, LF Sua, E Reisenbichler, Z Kos, ...
The Journal of pathology 250 (5), 667-684, 2020
1642020
Characterisation of microRNA expression in post-natal mouse mammary gland development
S Avril-Sassen, LD Goldstein, J Stingl, C Blenkiron, J Le Quesne, I Spiteri, ...
BMC genomics 10, 1-15, 2009
1592009
Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease
CT Hiley, J Le Quesne, G Santis, R Sharpe, DG de Castro, G Middleton, ...
The Lancet 388 (10048), 1002-1011, 2016
1582016
The malignant phenotype in breast cancer is driven by eIF4A1-mediated changes in the translational landscape
A Modelska, E Turro, R Russell, J Beaton, T Sbarrato, K Spriggs, J Miller, ...
Cell death & disease 6 (1), e1603-e1603, 2015
1562015
Identification of a motif that mediates polypyrimidine tract-binding protein-dependent internal ribosome entry
SA Mitchell, KA Spriggs, M Bushell, JR Evans, M Stoneley, ...
Genes & development 19 (13), 1556-1571, 2005
1552005
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma
L Au, E Hatipoglu, MR de Massy, K Litchfield, G Beattie, A Rowan, ...
Cancer cell 39 (11), 1497-1518. e11, 2021
1482021
TGFβ induces the formation of tumour-initiating cells in claudinlow breast cancer
A Bruna, W Greenwood, J Le Quesne, A Teschendorff, ...
Nature communications 3 (1), 1055, 2012
1272012
Long-fiber carbon nanotubes replicate asbestos-induced mesothelioma with disruption of the tumor suppressor gene Cdkn2a (Ink4a/Arf)
T Chernova, FA Murphy, S Galavotti, XM Sun, IR Powley, S Grosso, ...
Current Biology 27 (21), 3302-3314. e6, 2017
1212017
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