| A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK JM Enserink, AE Christensen, J de Rooij, M van Triest, F Schwede, ... Nature cell biology 4 (11), 901-906, 2002 | 838 | 2002 |
| Evaluation of the proteasome inhibitor MLN9708 in preclinical models of human cancer E Kupperman, EC Lee, Y Cao, B Bannerman, M Fitzgerald, A Berger, J Yu, ... Cancer research 70 (5), 1970-1980, 2010 | 619 | 2010 |
| Phospholipase C-β1 is a GTPase-activating protein for Gq/11, its physiologic regulator G Berstein, JL Blank, DY Jhon, JH Exton, SG Rhee, EM Ross Cell 70 (3), 411-418, 1992 | 604 | 1992 |
| Reconstitution of agonist-stimulated phosphatidylinositol 4, 5-bisphosphate hydrolysis using purified m1 muscarinic receptor, Gq/11, and phospholipase C-beta 1. G Berstein, JL Blank, AV Smrcka, T Higashijima, PC Sternweis, JH Exton, ... Journal of Biological Chemistry 267 (12), 8081-8088, 1992 | 415 | 1992 |
| The ups and downs of MEK kinase interactions C Hagemann, JL Blank Cellular signalling 13 (12), 863-875, 2001 | 382 | 2001 |
| Molecular Cloning of Mitogen-activated Protein/ERK Kinase Kinases (MEKK) 2 and 3: REGULATION OF SEQUENTIAL PHOSPHORYLATION PATHWAYS INVOLVING MITOGEN-ACTIVATED PROTEIN KINASE … JL Blank, P Gerwins, EM Elliott, S Sather, GL Johnson Journal of Biological Chemistry 271 (10), 5361-5368, 1996 | 326 | 1996 |
| A region of adenylyl cyclase 2 critical for regulation by G protein βγ subunits J Chen, M DeVivo, J Dingus, A Harry, J Li, J Sui, DJ Carty, JL Blank, ... Science 268 (5214), 1166-1169, 1995 | 323 | 1995 |
| Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway P Gerwins, LB Jonathan, GL Johnson Journal of Biological Chemistry 272 (13), 8288-8295, 1997 | 322 | 1997 |
| Activation of cytosolic phosphoinositide phospholipase C by G-protein beta gamma subunits JL Blank, KA Brattain, JH Exton Journal of Biological Chemistry 267 (32), 23069-23075, 1992 | 265 | 1992 |
| Purification and characterization of two G-proteins that activate the beta 1 isozyme of phosphoinositide-specific phospholipase C. Identification as members of the Gq class. JL Blank, AH Ross, JH Exton Journal of Biological Chemistry 266 (27), 18206-18216, 1991 | 249 | 1991 |
| The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2 MM Kwatra, DA Schwinn, J Schreurs, JL Blank, CM Kim, JL Benovic, ... Journal of Biological Chemistry 268 (13), 9161-9164, 1993 | 223 | 1993 |
| p38 Mitogen-activated protein kinase mediates cell death and p21-activated kinase mediates cell survival during chemotherapeutic drug-induced mitotic arrest K Deacon, P Mistry, J Chernoff, JL Blank, R Patel Molecular biology of the cell 14 (5), 2071-2087, 2003 | 203 | 2003 |
| p38 Mitogen-activated protein kinase mediates cell death and p21-activated kinase mediates cell survival during chemotherapeutic drug-induced mitotic arrest K Deacon, P Mistry, J Chernoff, JL Blank, R Patel Molecular biology of the cell 14 (5), 2071-2087, 2003 | 203 | 2003 |
| Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S β5-subunit C Blackburn, KM Gigstad, P Hales, K Garcia, M Jones, FJ Bruzzese, ... Biochemical Journal 430 (3), 461-476, 2010 | 175 | 2010 |
| Characterization of the mitogen-activated protein kinase kinase 4 (MKK4)/c-Jun NH2-terminal kinase 1 and MKK3/p38 pathways regulated by MEK kinases 2 and 3: MEK kinase 3 … K Deacon, JL Blank Journal of Biological Chemistry 272 (22), 14489-14496, 1997 | 165 | 1997 |
| MEK kinase 3 directly activates MKK6 and MKK7, specific activators of the p38 and c-Jun NH2-terminal kinases K Deacon, JL Blank Journal of Biological Chemistry 274 (23), 16604-16610, 1999 | 129 | 1999 |
| A domain for G protein coupling in carboxyl-terminal tail of rat angiotensin II receptor type 1A T Sano, K Ohyama, Y Yamano, Y Nakagomi, S Nakazawa, M Kikyo, ... Journal of Biological Chemistry 272 (38), 23631-23636, 1997 | 127 | 1997 |
| Group‐I metabotropic glutamate receptors, mGlu1a and mGlu5a, couple to extracellular signal‐regulated kinase (ERK) activation via distinct, but overlapping, signalling pathways S Thandi, JL Blank, RAJ Challiss Journal of neurochemistry 83 (5), 1139-1153, 2002 | 121 | 2002 |
| Genome-wide siRNA screen for modulators of cell death induced by proteasome inhibitor bortezomib S Chen, JL Blank, T Peters, XJ Liu, DM Rappoli, MD Pickard, S Menon, ... Cancer research 70 (11), 4318-4326, 2010 | 114 | 2010 |
| Novel DNA damage checkpoints mediating cell death induced by the NEDD8-activating enzyme inhibitor MLN4924 JL Blank, XJ Liu, K Cosmopoulos, DC Bouck, K Garcia, H Bernard, ... Cancer research 73 (1), 225-234, 2013 | 105 | 2013 |
