CRISPR genome surgery in a novel humanized model for autosomal dominant retinitis pigmentosa WH Wu, YT Tsai, IW Huang, CH Cheng, CW Hsu, X Cui, J Ryu, ... Molecular Therapy 30 (4), 1407-1420, 2022 | 21 | 2022 |
CRISPR/Cas therapeutic strategies for autosomal dominant disorders SM Caruso, PMJ Quinn, BL da Costa, SH Tsang The Journal of clinical investigation 132 (9), 2022 | 13 | 2022 |
Precision metabolome reprogramming for imprecision therapeutics in retinitis pigmentosa SM Caruso, J Ryu, PMJ Quinn, SH Tsang The Journal of Clinical Investigation 130 (8), 3971-3973, 2020 | 13 | 2020 |
Prime editing for the installation and correction of mutations causing inherited retinal disease: a brief methodology YT Tsai, BL da Costa, ND Nolan, SM Caruso, LA Jenny, SR Levi, ... Retinitis Pigmentosa, 313-331, 2022 | 6 | 2022 |
Renormalization of metabolic coupling treats age-related degenerative disorders: an oxidative RPE niche fuels the more glycolytic photoreceptors ND Nolan, SM Caruso, X Cui, SH Tsang Eye (London, England), 2022 | 6* | 2022 |
Generation of an Avian Myeloblastosis Virus (AMV) reverse transcriptase prime editor YT Tsai, BL da Costa, SM Caruso, ND Nolan, SR Levi, SH Tsang, ... Retinal Degenerative Diseases XIX: Mechanisms and Experimental Therapy, 109-114, 2023 | 2 | 2023 |
Targeting miR-181a/b in retinitis pigmentosa: implications for disease progression and therapy BL Costa, PMJ Quinn, WH Wu, S Liu, ND Nolan, A Demirkol, YT Tsai, ... Cell & Bioscience 14 (1), 64, 2024 | | 2024 |
Methods and Systems for Correcting Mutations in PRPH2 YT Tsai, SM Caruso, BLD Costa, SH Tsang, PMJ Quinn WO Patent WO/2023/220,732, 2023 | | 2023 |
Prime Editing Strategy to Install the PRPH2 c.828+1G>A Mutation SM Caruso, YT Tsai, BL da Costa, M Kolesnikova, LA Jenny, SH Tsang, ... Retinal Degenerative Diseases XIX: Mechanisms and Experimental Therapy, 97-102, 2023 | | 2023 |
Prime Editing Rescues Aberrant Splicing Defect Caused by Pathogenic Variants in PRPH2 PMJ Quinn, YT Tsai, SM Caruso, S Liu, Y Li, SH Tsang, BL da Costa Investigative Ophthalmology & Visual Science 64 (8), 3860-3860, 2023 | | 2023 |
Development of a Gene Augmentation Strategy for CRB1-mediated Inherited Retinal Diseases JA Imventarza, K Theodore, BL da Costa, SM Caruso, SH Tsang, YT Tsai, ... Investigative Ophthalmology & Visual Science 64 (8), 3843-3843, 2023 | | 2023 |