BIVV001, a new class of factor VIII replacement for hemophilia A that is independent of von Willebrand factor in primates and mice E Seth Chhabra, T Liu, J Kulman, S Patarroyo-White, B Yang, Q Lu, ... Blood, The Journal of the American Society of Hematology 135 (17), 1484-1496, 2020 | 76 | 2020 |
Intrinsic differences between FVIIIa mimetic bispecific antibodies and FVIII prevent assignment of FVIII‐equivalence NC Leksa, MM Aleman, AG Goodman, D Rabinovich, R Peters, J Salas Journal of Thrombosis and Haemostasis 17 (7), 1044-1052, 2019 | 26 | 2019 |
Inhibition of LILRB2 by a novel blocking antibody designed to reprogram immunosuppressive macrophages to drive T-cell activation in tumors B Umiker, Y Hashambhoy-Ramsay, J Smith, T Rahman, A Mueller, ... Molecular Cancer Therapeutics 22 (4), 471-484, 2023 | 8 | 2023 |
A combinatorial library approach to generate rFVIII variants with multiple XTEN insertions and improved pharmacokinetic properties T Liu, J Kulman, PYB Chang, S Patarroyo-White, D Drager, S Ding, ... Journal of Thrombosis and Haemostasis 11, 371-371, 2013 | 3 | 2013 |
Assessment of structural comparability between rFVIIIFc and unmodified B domain-deleted FVIII by complementary biophysical methods K John, S Tsutakawa, G Bou-Assaf, PL Chiu, ZL Liu, A Goodman, J Arndt, ... JOURNAL OF THROMBOSIS AND HAEMOSTASIS 11, 474-474, 2013 | 2 | 2013 |
Breaking barriers to access intracellular targets with T-cell engagers: Discovery of diverse, developable, and ultra-specific antibodies against a MAGE-A4 pMHC D Tortora, P Bergqvist, GP Leung, E Vigano, A Samiotakis, H Dhupar, ... Cancer Research 83 (7_Supplement), 1891-1891, 2023 | 1 | 2023 |
Assessing Structure-Activity Relationships in FVIII By Integration of Structural, Biophysical, and Biochemical Data Obtained with Anti-FVIII Antibodies ZL Liu, G Bou-Assaf, M Zhang, A Goodman, P Chiu, M Chambers, T Walz, ... Blood 124 (21), 4223, 2014 | 1 | 2014 |
A new class of coagulation factor VIII molecules that achieved four-fold longer half-life than recombinant FVIII in hemophilia A mice T Liu, SE Chhabra, J Kulman, L Zhu, S Patarroyo-White, D Drager, ... Journal of Thrombosis and Haemostasis 11, 71-71, 2013 | 1 | 2013 |
Characterization of a panel of anti-FVIII antibodies by domain specificity assignment, pairwise epitope overlap analysis, and determination of affinities for FVIII and rFVIIIFc ZL Liu, A Goodman, RT Peters, J Kulman JOURNAL OF THROMBOSIS AND HAEMOSTASIS 11, 843-844, 2013 | 1 | 2013 |
Development of PSMA x CD3 T-cell engagers using an integrated, functional approach V de Puyraimond, M Mai, A Amash, N Blamey, G Conaghan, JF Scortecci, ... Cancer Research 84 (6_Supplement), 6359-6359, 2024 | | 2024 |
Functional and specific T-cell engagers against a peptide-MHC tumor target D Tortora, P Bergqvist, A Goodman, R Blackler, N Blamey, S Carrara, ... Cancer Research 84 (6_Supplement), 2373-2373, 2024 | | 2024 |
Target-dependent considerations for the design of bispecific T-cell engagers B Varied | | 2024 |
1395 Targeting intracellular tumor antigens to Figureht cancer: discovery and development of functional and specific T-cell engagers against a MAGE-A4 pMHC D Tortora, P Bergqvist, T Jacobs, P Farber, R Blackler, A Samiotakis, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
1367 A rational approach to selecting CD3-binding antibodies for T-cell engager development JM Mai, V de Puyraimond, P Pouliot, K Caldwell, L Clifford, A Goodman, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
Bispecific antibodies binding to coagulation factor ix and coagulation factor x RT Peters, N Leksa, BR Pearse, J Kulman, M Aleman, A Goodman US Patent App. 16/462,878, 2023 | | 2023 |
Allosteric activation of factor IXa by an antibody binding to the protease domain J Arndt, A Goodman, K Knockenhauer, M Aleman, J Salas, R Peters, ... HAEMOPHILIA 24, 29-30, 2018 | | 2018 |
Thrombin digestion kinetics of BIIB073 (rFVIIIFc-VWF-XTEN) ES Chhabra, A Goodman, Q Lu, A Holthaus, A Ismail, V Schellenberger, ... HAEMOPHILIA 22, 19-20, 2016 | | 2016 |
Recombinant FIX/X-Bp from the Japanese Habu Snake Is a Universal Ligand for Purification of Highly Carboxylated Factor IX Variants and Factor X O Mercury, L Liu, A Ismail, M Zhang, Q Lu, TO Cameron, A Goodman, ... Blood 126 (23), 1081, 2015 | | 2015 |
Evidence For Flexible Tethering Of Fc To FVIII In Recombinant FVIII-Fc Fusion Protein rFVIIIFc N Leksa, L Liu, A Goodman, P Chiu, T Walz, R Peters, J Kulman Blood 122 (21), 1102, 2013 | | 2013 |
Identification of structurally permissive regions in coagulation factor VIII suitable for the insertion of exogenous peptidyl elements K John, T Liu, PY Chang, S Ding, S Patarroyo-White, A Goodman, ... JOURNAL OF THROMBOSIS AND HAEMOSTASIS 11, 974-974, 2013 | | 2013 |