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Khyati Meghani
Khyati Meghani
Verified email at u.northwestern.edu
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Cited by
Year
DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells
YJ He, K Meghani, MC Caron, C Yang, DA Ronato, J Bian, A Sharma, ...
Nature 563 (7732), 522-526, 2018
1942018
Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13
M Zeng, NP Kwiatkowski, T Zhang, B Nabet, M Xu, Y Liang, C Quan, ...
Elife 7, e39030, 2018
1422018
Platinum and PARP inhibitor resistance due to overexpression of microRNA-622 in BRCA1-mutant ovarian cancer
YE Choi, K Meghani, ME Brault, L Leclerc, YJ He, TA Day, KM Elias, ...
Cell reports 14 (3), 429-439, 2016
1422016
TIRR regulates 53BP1 by masking its histone methyl-lysine binding function
P Drané, ME Brault, G Cui, K Meghani, S Chaubey, A Detappe, ...
Nature 543 (7644), 211-216, 2017
1262017
Evolutionarily conserved serum microRNAs predict radiation-induced fatality in nonhuman primates
W Fendler, B Malachowska, K Meghani, PA Konstantinopoulos, C Guha, ...
Science translational medicine 9 (379), eaal2408, 2017
782017
Multifaceted impact of microRNA 493-5p on genome-stabilizing pathways induces platinum and PARP inhibitor resistance in BRCA2-mutated carcinomas
K Meghani, W Fuchs, A Detappe, P Drané, E Gogola, S Rottenberg, ...
Cell reports 23 (1), 100-111, 2018
712018
First-in-human intravesical delivery of pembrolizumab identifies immune activation in bladder cancer unresponsive to Bacillus Calmette-Guérin
K Meghani, LF Cooley, B Choy, M Kocherginsky, S Swaminathan, ...
European urology 82 (6), 602-610, 2022
342022
Expression-based subtypes define pathologic response to neoadjuvant immune-checkpoint inhibitors in muscle-invasive bladder cancer
AG Robertson, K Meghani, LF Cooley, KA McLaughlin, LA Fall, Y Yu, ...
Nature communications 14 (1), 2126, 2023
182023
Immune activation is essential for the antitumor activity of EZH2 inhibition in urothelial carcinoma
A Piunti, K Meghani, Y Yu, AG Robertson, JR Podojil, KA McLaughlin, ...
Science advances 8 (40), eabo8043, 2022
172022
Biodegradable nanoparticles induce cGAS/STING-dependent reprogramming of myeloid cells to promote tumor immunotherapy
JR Podojil, AC Cogswell, MY Chiang, V Eaton, I Ifergan, T Neef, D Xu, ...
Frontiers in immunology 13, 887649, 2022
62022
Role of chromatin modifying complexes and therapeutic opportunities in bladder cancer
K Meghani, L Folgosa Cooley, A Piunti, JJ Meeks
Bladder Cancer 8 (2), 101-112, 2022
52022
Somatic mutations of MLL4/COMPASS induce cytoplasmic localization providing molecular insight into cancer prognosis and treatment
Z Zhao, Y Aoi, CN Philips, KA Meghani, SR Gold, Y Yu, LS John, J Qian, ...
Proceedings of the National Academy of Sciences 120 (52), e2310063120, 2023
32023
Spatial comparison of molecular features associated with resistance to pembrolizumab in BCG unresponsive bladder cancer
K Meghani, N Frydenlund, Y Yu, B Choy, JJ Meeks
Journal for immunotherapy of cancer 12 (4), 2024
12024
Abstract GMM-027: DYNLL1 INHIBITS DNA END RESECTION IN BRCA1-DEFICIENT CELLS AND REGULATES PARP INHIBITOR SENSITIVITY
YJ He, K Meghani, MC Caron, C Yang, DA Ronato, J Bian, A Sharma, ...
Clinical Cancer Research 25 (22_Supplement), GMM-027-GMM-027, 2019
12019
Abstract PR011: Imaging mass cytometry captures patient heterogeneity enabling BCG response stratification in non-muscle invasive bladder cancer
AF Pour, D Baker, S Sivajothi, B Choy, K Meghani, Y Yu, LA Fall, B Ristau, ...
Clinical Cancer Research 30 (10_Supplement), PR011-PR011, 2024
2024
Biodegradable nanoparticle-induced sting pathway activation for the treatment of cancer.
J Podojil, A Cogswell, MY Chiang, V Eaton, I Efergan, T Neef, D Xu, ...
Journal of Clinical Oncology 40 (16_suppl), e14552-e14552, 2022
2022
PD12-06 DIFFERENTIAL MYELOID INFLAMMATORY RESPONSE AND TUMORIGENESIS BY GENDER IN MOUSE MODEL OF BLADDER CANCER
LF Cooley, J Podojil, K Meghani, Y Yu, S Miller, J Meeks
The Journal of Urology 207 (Supplement 5), e197, 2022
2022
PD42-08 DIFFERENTIAL MYELOID DERIVED SUPPRESSOR CELL RECRUITMENT AND TUMORIGENESIS BY GENDER IN MOUSE MODEL OF BLADDER CANCER
LF Cooley, J Podojil, K Meghani, Y Yu, SD Miller, JJ Meeks
Journal of Urology 206 (Supplement 3), e727, 2021
2021
DYNLL1 INHIBITS DNA END RESECTION IN BRCA1-DEFICIENT CELLS AND REGULATES PARP INHIBITOR SENSITIVITY
YJ He, K Meghani, MC Caron, C Yang, DA Ronato, J Bian, A Sharma, ...
CLINICAL CANCER RESEARCH 25 (22), 90-90, 2019
2019
MicroRNA profiling to identify novel determinants of platinum resistance in BRCA1/2-mutated high-grade serous ovarian cancer
K Meghani, E Gogola, S Rottenberg, J Jonkers, U Matulonis, E Swisher, ...
CANCER RESEARCH 77, 2017
2017
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