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Olga  Spadaro
Olga Spadaro
Senior Scientist at AstraZeneca
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing
CD Camell, J Sander, O Spadaro, A Lee, KY Nguyen, A Wing, ...
Nature 550 (7674), 119-123, 2017
3782017
IGF1 shapes macrophage activation in response to immunometabolic challenge
O Spadaro, CD Camell, L Bosurgi, KY Nguyen, YH Youm, CV Rothlin, ...
Cell reports 19 (2), 225-234, 2017
1702017
Aging induces an Nlrp3 inflammasome-dependent expansion of adipose B cells that impairs metabolic homeostasis
CD Camell, P Günther, A Lee, EL Goldberg, O Spadaro, YH Youm, ...
Cell metabolism 30 (6), 1024-1039. e6, 2019
1502019
Caloric restriction in humans reveals immunometabolic regulators of health span
O Spadaro, Y Youm, I Shchukina, S Ryu, S Sidorov, A Ravussin, ...
Science 375 (6581), 671-677, 2022
1422022
Growth hormone receptor deficiency protects against age-related NLRP3 inflammasome activation and immune senescence
O Spadaro, EL Goldberg, CD Camell, YH Youm, JJ Kopchick, KY Nguyen, ...
Cell reports 14 (7), 1571-1580, 2016
852016
IL-27 signalling promotes adipocyte thermogenesis and energy expenditure
Q Wang, D Li, G Cao, Q Shi, J Zhu, M Zhang, H Cheng, Q Wen, H Xu, ...
Nature 600 (7888), 314-318, 2021
782021
Pathogenesis of hypothyroidism-induced NAFLD is driven by intra-and extrahepatic mechanisms
G Ferrandino, RR Kaspari, O Spadaro, A Reyna-Neyra, RJ Perry, ...
Proceedings of the National Academy of Sciences 114 (43), E9172-E9180, 2017
662017
Functional analysis of the murine Pax8 promoter reveals autoregulation and the presence of a novel thyroid-specific DNA-binding activity
A Di Gennaro, O Spadaro, MG Baratta, M De Felice, R Di Lauro
Thyroid 23 (4), 488-496, 2013
182013
DNAJC17 is localized in nuclear speckles and interacts with splicing machinery components
A Pascarella, G Ferrandino, SC Credendino, C Moccia, F D’Angelo, ...
Scientific Reports 8 (1), 7794, 2018
132018
Aging induces Nlrp3 inflammasome dependent adipose B cell expansion to impair metabolic homeostasis
CD Camell, A Lee, P Günther, EL Goldberg, O Spadaro, YH Youm, ...
bioRxiv, 607192, 2019
42019
Gaining weight: insulin-eating islet macrophages
O Spadaro, VD Dixit
Immunity 50 (1), 13-15, 2019
42019
Reduction of SPARC protects mice against NLRP3 inflammasome activation and obesity
S Ryu, O Spadaro, S Sidorov, AH Lee, S Caprio, C Morrison, SR Smith, ...
The Journal of clinical investigation 133 (19), 2023
32023
NLRP3 Inflammasome controls adipose tissue macrophage activation during aging
C Camell, J Sander, O Spadaro, A Lee, KY Nguyen, A Wing, EL Goldberg, ...
The Journal of Immunology 198 (1_Supplement), 154.3-154.3, 2017
12017
Activation of transsulfuration pathway to maintain cysteine is a thermogenic checkpoint for the conservation of energy
V Dixit, A Lee, Y Sugiura, YH Youm, T Dlugos, R Maeda, D Coman, ...
2023
SUN-097 AgRP Neurons Determine Survival in Activity-Based Anorexia Model
MC Miletta, M Shanabrough, M Sestan-Pesa, L Varela, G Mancini, ...
Journal of the Endocrine Society 3 (Supplement_1), SUN-097, 2019
2019
NLRP3 inflammasome controls adipose tissue leukocytosis and inflammation during aging (INM6P. 331)
C Camell, YH Youm, K Nguyen, A Ravussin, O Spadaro, V Dixit
The Journal of Immunology 194 (1_Supplement), 193.5-193.5, 2015
2015
A new gene predisposing to congenital hypothyroidism
A Pascarella, G Ferrandino, M Basile, O Spadaro, F D'Angelo, ...
EUROPEAN THYROID JOURNAL 3 (s1), 86-86, 2014
2014
DNAJCͷͽ is localized in nuclear speckles and interacts with splicing machinery components
A Pascarellaͷ, G Ferrandino, SC Credendinoͷ, C Mocciaͷ, F D’Angelo, ...
Analysis of a novel thyroid-specific DNA binding activity in the Pax8 promoter
P De Girolamo, R Di Lauro, O Spadaro
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Articles 1–19