Engineering CAR-T cells to activate small-molecule drugs in situ TJ Gardner, JP Lee, CM Bourne, D Wijewarnasuriya, N Kinarivala, ... Nature chemical biology 18 (2), 216-225, 2022 | 49 | 2022 |
ALK and RET inhibitors promote HLA class I antigen presentation and unmask new antigens within the tumor immunopeptidome CY Oh, MG Klatt, C Bourne, T Dao, MM Dacek, EJ Brea, SS Mun, ... Cancer immunology research 7 (12), 1984-1997, 2019 | 41 | 2019 |
Targeted cellular micropharmacies: cells engineered for localized drug delivery TJ Gardner, CM Bourne, MM Dacek, K Kurtz, M Malviya, L Peraro, ... Cancers 12 (8), 2175, 2020 | 21 | 2020 |
Tumor-associated antigen PRAME exhibits dualistic functions that are targetable in diffuse large B cell lymphoma K Takata, LC Chong, D Ennishi, T Aoki, MY Li, A Thakur, S Healy, ... The Journal of Clinical Investigation 132 (10), 2022 | 18 | 2022 |
Low-dose CDK4/6 inhibitors induce presentation of pathway specific MHC ligands as potential targets for cancer immunotherapy A Charles, CM Bourne, T Korontsvit, ZEH Aretz, SS Mun, T Dao, MG Klatt, ... Oncoimmunology 10 (1), 1916243, 2021 | 17 | 2021 |
Incorporation of bacterial immunoevasins to protect cell therapies from host antibody-mediated immune rejection L Peraro, CM Bourne, MM Dacek, E Akalin, JH Park, EL Smith, ... Molecular Therapy 29 (12), 3398-3409, 2021 | 15 | 2021 |
Potentiating antibody-dependent killing of cancers with CAR T cells secreting CD47-SIRPα checkpoint blocker MM Dacek, KG Kurtz, P Wallisch, SA Pierre, S Khayat, CM Bourne, ... Blood 141 (16), 2003-2015, 2023 | 12 | 2023 |
A TCR mimic CAR T cell specific for NDC80 is broadly reactive with solid tumors and hematologic malignancies MG Klatt, T Dao, Z Yang, J Liu, SS Mun, MM Dacek, H Luo, TJ Gardner, ... Blood, The Journal of the American Society of Hematology 140 (8), 861-874, 2022 | 10 | 2022 |
Unmasking the suppressed immunopeptidome of EZH2-mutated diffuse large B-cell lymphomas through combination drug treatment CM Bourne, SS Mun, T Dao, ZEH Aretz, Z Molvi, RS Gejman, A Daman, ... Blood Advances 6 (14), 4107-4121, 2022 | 8 | 2022 |
The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases PM Exconde, C Hernandez-Chavez, CM Bourne, RM Richards, MB Bray, ... Cell Reports 42 (12), 2023 | 7 | 2023 |
Engineering CAR-T cells for radiohapten capture in imaging and radioimmunotherapy applications K Kurtz, L Eibler, MM Dacek, LM Carter, DR Veach, S Lovibond, ... Theranostics 13 (15), 5469, 2023 | 4 | 2023 |
Harnessing Pyroptosis for Cancer Immunotherapy CM Bourne, CY Taabazuing Cells 13 (4), 346, 2024 | 3 | 2024 |
Regulators of the secretory pathway have distinct inputs into single-celled branching morphogenesis and seamless tube formation in the Drosophila trachea CM Bourne, DC Lai, J Schottenfeld-Roames Developmental biology 490, 100-109, 2022 | 3 | 2022 |
Mechanisms of adoptive T cell micropharmacies C Bourne, T Gardner, J Romero-Pichardo, P Lee, M Dacek, D Tan, ... MOLECULAR THERAPY 28 (4), 16-16, 2020 | 2 | 2020 |
Host Interactions with Engineered T-cell Micropharmacies CM Bourne, P Wallisch, MM Dacek, TJ Gardner, S Pierre, K Vogt, ... Cancer Immunology Research 11 (9), 1253-1265, 2023 | 1 | 2023 |
The Tumor Associated Antigen PRAME Exhibits Dualistic Functions That Are Targetable in Diffuse Large B-Cell Lymphoma K Takata, LC Chong, D Ennishi, A Thakur, S Healy, E Vigano, T Dao, ... Blood 136, 34, 2020 | 1 | 2020 |
A TCR mimic antibody-directed CAR T cell specific for intracellular NDC80 is broadly cancer reactive and displays high activity against hematological malignancies MG Klatt, Z Yang, J Liu, T Korontsvit, SS Mun, L Peraro, TJ Gardner, ... Blood 136, 20-21, 2020 | 1 | 2020 |
Inflammatory caspase substrate specificities PM Exconde, CM Bourne, M Kulkarni, BM Discher, CY Taabazuing Mbio, e02975-23, 2024 | | 2024 |
Host-cell Interactions of Engineered T cell Micropharmacies CM Bourne, P Wallisch, M Dacek, T Gardner, S Pierre, K Vogt, BC Corless, ... bioRxiv, 2023 | | 2023 |
Black in Cancer: Two Years of Empowering the Next Generation CM Bourne, HJ Henderson, E White, J Morris, MA Bah, R Harewood, ... Cancer Discovery 13 (2), 275-277, 2023 | | 2023 |