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Elva Morretta, Ph.D.
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Exosomal CD73 from serum of patients with melanoma suppresses lymphocyte functions and is associated with therapy resistance to anti-PD-1 agents
R Turiello, M Capone, E Morretta, MC Monti, G Madonna, R Azzaro, ...
Journal for Immunotherapy of Cancer 10 (3), 2022
452022
Serum CD73 is a prognostic factor in patients with metastatic melanoma and is associated with response to anti-PD-1 therapy
R Turiello, M Capone, D Giannarelli, E Morretta, MC Monti, G Madonna, ...
Journal for Immunotherapy of Cancer 8 (2), 2020
372020
Opposite effects of the FXR agonist obeticholic acid on Mafg and Nrf2 mediate the development of acute liver injury in rodent models of cholestasis
A Carino, M Biagioli, S Marchianò, C Fiorucci, M Bordoni, R Roselli, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2020
302020
Discovering the Biological Target of 5-epi-Sinuleptolide Using a Combination of Proteomic Approaches
E Morretta, R Esposito, C Festa, R Riccio, A Casapullo, MC Monti
Marine Drugs 15 (10), 312, 2017
252017
Transcriptome analysis of dual FXR and GPBAR1 agonism in rodent model of NASH reveals modulation of lipid droplets formation
A Carino, S Marchianò, M Biagioli, C Fiorucci, A Zampella, MC Monti, ...
Nutrients 11 (5), 1132, 2019
242019
Serum bile acid levels before and after sleeve gastrectomy and their correlation with obesity-related comorbidities
S De Vuono, MA Ricci, E Nulli Migliola, MC Monti, E Morretta, M Boni, ...
Obesity surgery 29, 2517-2526, 2019
212019
Drug repositioning for Fabry disease: acetylsalicylic acid potentiates the stabilization of lysosomal alpha-galactosidase by pharmacological chaperones
M Monticelli, L Liguori, M Allocca, A Bosso, G Andreotti, J Lukas, ...
International journal of molecular sciences 23 (9), 5105, 2022
152022
Crellastatin A, a PARP‐1 Inhibitor Discovered by Complementary Proteomic Approaches
E Morretta, A Tosco, C Festa, M Mozzicafreddo, MC Monti, A Casapullo
ChemMedChem 15 (3), 317-323, 2020
152020
Beneficial effects of UDCA and norUDCA in a rodent model of steatosis are linked to modulation of GPBAR1/FXR signaling
S Marchianò, M Biagioli, R Roselli, A Zampella, C Di Giorgio, M Bordoni, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2022
132022
Involvement of 3′, 5′‐cyclic inosine monophosphate in cystathionine γ‐lyase‐dependent regulation of the vascular tone
E Mitidieri, V Vellecco, V Brancaleone, D Vanacore, OL Manzo, E Martin, ...
British Journal of Pharmacology 178 (18), 3765-3782, 2021
132021
Mesoglycan exerts its fibrinolytic effect through the activation of annexin A2.
R Belvedere, E Morretta, E Pessolano, N Novizio, A Tosco, A Porta, ...
Journal of Cellular Physiology 236 (7), 4926-4943, 2020
132020
Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASH
S Marchianò, M Biagioli, E Morretta, C Di Giorgio, R Roselli, M Bordoni, ...
Scientific reports 13 (1), 1602, 2023
122023
Atorvastatin protects against liver and vascular damage in a model of diet induced steatohepatitis by resetting FXR and GPBAR1 signaling
S Marchianò, M Biagioli, R Roselli, A Zampella, C Di Giorgio, M Bordoni, ...
The FASEB Journal 36 (1), e22060, 2022
122022
Novel insights on the molecular mechanism of action of the anti-angiogenic pyrazolyl-urea GeGe-3 by functional proteomics
E Morretta, R Belvedere, A Petrella, A Spallarossa, F Rapetti, O Bruno, ...
Bioorganic Chemistry 115, 105168, 2021
112021
Carbamoyl-phosphate synthase 1 as a novel target of phomoxanthone A, a bioactive fungal metabolite
S Ceccacci, J Deitersen, M Mozzicafreddo, E Morretta, P Proksch, ...
Biomolecules 10 (6), 846, 2020
112020
Synthesis, functional proteomics and biological evaluation of new 5-pyrazolyl ureas as potential anti-angiogenic compounds
E Morretta, A Sidibè, A Spallarossa, A Petrella, E Meta, O Bruno, ...
European Journal of Medicinal Chemistry 226, 113872, 2021
82021
Curcumin Has Beneficial Effects on Lysosomal Alpha-Galactosidase: Potential Implications for the Cure of Fabry Disease
M Monticelli, B Hay Mele, M Allocca, L Liguori, J Lukas, MC Monti, ...
International Journal of Molecular Sciences 24 (2), 1095, 2023
72023
Label-Free Quantitative Proteomics to Explore the Action Mechanism of the Pharmaceutical-Grade Triticum vulgare Extract in Speeding Up Keratinocyte Healing
E Morretta, A D’Agostino, E Cassese, B Maglione, A Petrella, C Schiraldi, ...
Molecules 27 (3), 1108, 2022
72022
The Pyrazolyl-Urea Gege3 Inhibits the Activity of ANXA1 in the angiogenesis induced by the pancreatic cancer derived EVs
R Belvedere, E Morretta, N Novizio, S Morello, O Bruno, C Brullo, ...
Biomolecules 11 (12), 1758, 2021
62021
Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma
C Di Giorgio, R Bellini, A Lupia, C Massa, M Bordoni, S Marchianò, ...
Frontiers in Oncology 13, 1140730, 2023
52023
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Articles 1–20