The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1 Y Sancak, TR Peterson, YD Shaul, RA Lindquist, CC Thoreen, ... Science 320 (5882), 1496-1501, 2008 | 3071 | 2008 |
PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase Y Sancak, CC Thoreen, TR Peterson, RA Lindquist, SA Kang, E Spooner, ... Molecular cell 25 (6), 903-915, 2007 | 1627 | 2007 |
DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival TR Peterson, M Laplante, CC Thoreen, Y Sancak, SA Kang, WM Kuehl, ... Cell 137 (5), 873-886, 2009 | 1569 | 2009 |
Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress S Sengupta, TR Peterson, DM Sabatini Molecular cell 40 (2), 310-322, 2010 | 1526 | 2010 |
mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway TR Peterson, SS Sengupta, TE Harris, AE Carmack, SA Kang, E Balderas, ... Cell 146 (3), 408-420, 2011 | 1309 | 2011 |
The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling PP Hsu, SA Kang, J Rameseder, Y Zhang, KA Ottina, D Lim, TR Peterson, ... science 332 (6035), 1317-1322, 2011 | 1202 | 2011 |
mTORC1 controls fasting-induced ketogenesis and its modulation by ageing S Sengupta, TR Peterson, M Laplante, S Oh, DM Sabatini Nature 468 (7327), 1100-1104, 2010 | 677 | 2010 |
MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors K Birsoy, T Wang, R Possemato, OH Yilmaz, CE Koch, WW Chen, ... Nature genetics 45 (1), 104-108, 2013 | 270 | 2013 |
Mapping the genetic landscape of human cells MA Horlbeck, A Xu, M Wang, NK Bennett, CY Park, D Bogdanoff, ... Cell 174 (4), 953-967. e22, 2018 | 254 | 2018 |
ER stress inhibits mTORC2 and Akt signaling through GSK-3β–mediated phosphorylation of Rictor CH Chen, T Shaikenov, TR Peterson, R Aimbetov, AK Bissenbaev, ... Science signaling 4 (161), ra10-ra10, 2011 | 170 | 2011 |
Postprandial hepatic lipid metabolism requires signaling through Akt2 independent of the transcription factors FoxA2, FoxO1, and SREBP1c M Wan, KF Leavens, D Saleh, RM Easton, DA Guertin, TR Peterson, ... Cell metabolism 14 (4), 516-527, 2011 | 149 | 2011 |
Rictor phosphorylation on the Thr-1135 site does not require mammalian target of rapamycin complex 2 D Boulbes, CH Chen, T Shaikenov, NK Agarwal, TR Peterson, TA Addona, ... Molecular Cancer Research 8 (6), 896-906, 2010 | 94 | 2010 |
Landscape infrastructure: case studies by SWA YY Hung, G Aquino, C Waldheim, J Czerniak, A Geuze, M Skjonsberg, ... De Gruyter, 2011 | 63 | 2011 |
Paradoxical expression of INK4c in proliferative multiple myeloma tumors: bi-allelic deletion vs increased expression A Dib, TR Peterson, L Raducha-Grace, A Zingone, F Zhan, I Hanamura, ... Cell Division 1, 1-10, 2006 | 47 | 2006 |
Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates Z Yu, LE Surface, CY Park, MA Horlbeck, GA Wyant, M Abu-Remaileh, ... Elife 7, e36620, 2018 | 46 | 2018 |
eIF3: a connecTOR of S6K1 to the translation preinitiation complex TR Peterson, DM Sabatini Molecular cell 20 (5), 655-657, 2005 | 30 | 2005 |
ATRAID regulates the action of nitrogen-containing bisphosphonates on bone LE Surface, DT Burrow, J Li, J Park, S Kumar, C Lyu, N Song, Z Yu, ... Science translational medicine 12 (544), eaav9166, 2020 | 16 | 2020 |
Bone turnover with venlafaxine treatment in older adults with depression KS Rawson, D Dixon, R Civitelli, TR Peterson, BH Mulsant, ... Journal of the American Geriatrics Society 65 (9), 2057-2063, 2017 | 16 | 2017 |
mTORC1 regulates cytokinesis through activation of Rho-ROCK signaling TR Peterson, M Laplante, E Van Veen, M Van Vugt, CC Thoreen, ... arXiv preprint arXiv:1506.04437, 2015 | 5 | 2015 |
Moonshots for aging S Kumar, TR Peterson Nutrition and Healthy Aging 5 (4), 239-246, 2020 | 4 | 2020 |