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Nikhil R. Tasker, Ph.D.
Nikhil R. Tasker, Ph.D.
Givaudan
Verified email at pitt.edu
Title
Cited by
Cited by
Year
Biosynthesis, total synthesis, and biological profiles of Ergot alkaloids
NR Tasker, P Wipf
The Alkaloids: Chemistry and Biology 85, 1-112, 2021
342021
A Short Synthesis of Ergot Alkaloids and Evaluation of the 5-HT1/2 Receptor Selectivity of Lysergols and Isolysergols
NR Tasker, P Wipf
Organic letters 24 (40), 7255-7259, 2022
202022
Tapping the therapeutic potential of protein tyrosine phosphatase 4A with small molecule inhibitors
NR Tasker, EJ Rastelli, JC Burnett, ER Sharlow, JS Lazo, P Wipf
Bioorganic & medicinal chemistry letters 29 (16), 2008-2015, 2019
162019
Next-generation cell-active inhibitors of the undrugged oncogenic PTP4A3 phosphatase
JS Lazo, IK Blanco, NR Tasker, EJ Rastelli, JC Burnett, SR Garrott, ...
Journal of Pharmacology and Experimental Therapeutics 371 (3), 652-662, 2019
142019
In-flow photooxygenation of aminothienopyridinones generates iminopyridinedione PTP4A3 phosphatase inhibitors
NR Tasker, EJ Rastelli, IK Blanco, JC Burnett, ER Sharlow, JS Lazo, ...
Organic & Biomolecular Chemistry 17 (9), 2448-2466, 2019
142019
Credentialing and pharmacologically targeting PTP4A3 phosphatase as a molecular target for ovarian cancer
JS Lazo, ER Sharlow, R Cornelison, DJ Hart, DC Llaneza, AJ Mendelson, ...
Biomolecules 11 (7), 969, 2021
112021
Structure of the complex of an iminopyridinedione protein tyrosine phosphatase 4A3 phosphatase inhibitor with human serum albumin
MP Czub, AM Boulton, EJ Rastelli, NR Tasker, TS Maskrey, IK Blanco, ...
Molecular Pharmacology 98 (6), 648-657, 2020
102020
Biological studies of clavine alkaloids targeting CNS receptors
NR Tasker, EJ Pazur, P Wipf
Frontiers in psychiatry 14, 1286941, 2023
52023
C3-Functionalization of indoles with α-heteroaryl-substituted methyl alcohols
EJ Pazur, NR Tasker, P Wipf
Organic & Biomolecular Chemistry 21 (43), 8651-8657, 2023
42023
Photoflow preparation of PTP4A3 inhibitors, and concise total syntheses of ergot and clavine alkaloids
NR Tasker
University of Pittsburgh, 2023
32023
Concise total syntheses of lysergene, lysergine, isolysergine and festuclavine
NR Tasker, P Wipf
Arkivoc 202312120, 2024
22024
Synthesis and Biological Analysis of Iso-dimethyltryptamines in a Model of Light-Induced Retinal Degeneration
EJ Pazur, A Kalatanova, NR Tasker, K Vainionpää, H Leinonen, ...
ACS Medicinal Chemistry Letters, 2024
12024
Selective psychedelic compounds
P Wipf, NR Tasker, EJ Pazur
US Patent App. 18/682,031, 2024
2024
Synthesis of Iso-Dimethyltryptamines and Biological Analysis in a Model of Light-Induced Retinal Degeneration
E Pazur, N Tasker, K Vainionpää, A Kalatanova, H Leinonen, P Wipf
2024
Direct C3-functionalization of indoles with alpha-heteroaryl-substituted methyl alcohols via a metal-free hydrogen autotransfer-type reaction
E Pazur, N Tasker, P Wipf
2023
Shortest Synthesis of Lysergol and its Binding to 5-HT1/2Receptors
NR Tasker, P Wipf
Synfacts 19 (01), 0109, 2023
2023
In-flow photooxygenation of aminothienopyridinones generates novel ptp4a3 phosphatase inhibitors
JS Lazo, E Sharlow, P Wipf, N Tasker, E Rastelli
US Patent App. 17/309,259, 2022
2022
In-flow photooxygenation of aminothienopyridinones generates novel ptp4a3 phosphatase inhibitors
JS Lazo, E Sharlow, P Wipf, N Tasker, E Rastelli
US Patent App. 17/309,260, 2021
2021
Structure of the Complex of an Iminopyridinedione Protein Tyrosine Phosphatase 4A3 Phosphatase Inhibitor with Human Serum Albumin (vol 98, pg 648, 2020)
MP Czub, AM Boulton, EJ Rastelli, NR Tasker, TS Maskrey, IK Blanco, ...
MOLECULAR PHARMACOLOGY 98 (6), 781-781, 2020
2020
Small molecule PTP4A3 phosphatase inhibitors targeting acute myeloid leukemia
J Lazo, N Tasker, E Rastelli, P Wipf, E Sharlow
European Journal of Cancer 138, S55-S56, 2020
2020
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