The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer SJ Vervoort, SA Welsh, JR Devlin, E Barbieri, DA Knight, S Offley, ... Cell 184 (12), 3143-3162. e32, 2021 | 115 | 2021 |
The tumor suppressor ARID1A controls global transcription via pausing of RNA polymerase II M Trizzino, E Barbieri, A Petracovici, S Wu, SA Welsh, TA Owens, ... Cell reports 23 (13), 3933-3945, 2018 | 91 | 2018 |
Targeted enhancer activation by a subunit of the integrator complex E Barbieri, M Trizzino, SA Welsh, TA Owens, B Calabretta, M Carroll, ... Molecular cell 71 (1), 103-116. e7, 2018 | 56 | 2018 |
Tagging methyl-CpG-binding domain proteins reveals different spatiotemporal expression and supports distinct functions KH Wood, BS Johnson, SA Welsh, JY Lee, Y Cui, E Krizman, ES Brodkin, ... Epigenomics 8 (4), 455-473, 2016 | 34 | 2016 |
Genomic regulation of transcription and RNA processing by the multitasking Integrator complex SA Welsh, A Gardini Nature Reviews Molecular Cell Biology 24 (3), 204-220, 2023 | 29 | 2023 |
Inability to switch from ARID1A-BAF to ARID1B-BAF impairs exit from pluripotency and commitment towards neural crest formation in ARID1B-related … L Pagliaroli, P Porazzi, AT Curtis, C Scopa, HMM Mikkers, C Freund, ... Nature Communications 12 (1), 6469, 2021 | 17 | 2021 |
A combinatorial approach to uncover an additional Integrator subunit SR Offley, MM Pfleiderer, A Zucco, A Fraudeau, SA Welsh, M Razew, ... Cell reports 42 (3), 2023 | 8 | 2023 |
A PP2A-Integrator complex fine-tunes transcription by opposing CDK9 SJ Vervoort, SA Welsh, JR Devlin, E Barbieri, DA Knight, M Costacurta, ... BioRxiv, 2020.07. 12.199372, 2020 | 3 | 2020 |
The Integrator Complex: A Multi-Tool for Metazoan Transcription SA Welsh University of Pennsylvania, 2021 | | 2021 |
Twist, Snail, and Sox9 form an allosterically regulated complex, the EMTosome, on a bipartite E-box site DS McCracken University of Pennsylvania, 2020 | | 2020 |