RAS oncogenes: weaving a tumorigenic web Y Pylayeva-Gupta, E Grabocka, D Bar-Sagi Nature Reviews Cancer 11 (11), 761-774, 2011 | 2139 | 2011 |
Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells C Commisso, SM Davidson, RG Soydaner-Azeloglu, SJ Parker, ... Nature 497 (7451), 633-637, 2013 | 1671 | 2013 |
Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein JJ Kamphorst, M Nofal, C Commisso, SR Hackett, W Lu, E Grabocka, ... Cancer research 75 (3), 544-553, 2015 | 831 | 2015 |
Mutant KRAS enhances tumor cell fitness by upregulating stress granules E Grabocka, D Bar-Sagi Cell 167 (7), 1803-1813. e12, 2016 | 172 | 2016 |
Wild-type H-and N-Ras promote mutant K-Ras-driven tumorigenesis by modulating the DNA damage response E Grabocka, Y Pylayeva-Gupta, MJK Jones, V Lubkov, E Yemanaberhan, ... Cancer cell 25 (2), 243-256, 2014 | 159 | 2014 |
Molecular Pathways: Targeting the Dependence of Mutant RAS Cancers on the DNA Damage Response E Grabocka, C Commisso, D Bar-Sagi Clinical cancer research 21 (6), 1243-1247, 2015 | 53 | 2015 |
Stress granules in cancer MS Song, E Grabocka Organelles in Disease, 25-52, 2020 | 44 | 2020 |
Disruption of oligomerization induces nucleocytoplasmic shuttling of leukemia-associated rho Guanine-nucleotide exchange factor E Grabocka, PB Wedegaertner Molecular pharmacology 72 (4), 993-1002, 2007 | 35 | 2007 |
Stress granules determine the development of obesity-associated pancreatic cancer G Fonteneau, A Redding, H Hoag-Lee, ES Sim, S Heinrich, MM Gaida, ... Cancer discovery 12 (8), 1984-2005, 2022 | 34 | 2022 |
Leukemia-associated RhoGEF (LARG) is a novel RhoGEF in cytokinesis and required for the proper completion of abscission MK Martz, E Grabocka, N Beeharry, TJ Yen, PB Wedegaertner Molecular biology of the cell 24 (18), 2785-2794, 2013 | 33 | 2013 |
Functional consequences of Gα13 mutations that disrupt interaction with p115RhoGEF E Grabocka, PB Wedegaertner Oncogene 24 (13), 2155-2165, 2005 | 32 | 2005 |
Histological image processing features induce a quantitative characterization of chronic tumor hypoxia A Sundstrom, E Grabocka, D Bar-Sagi, B Mishra PloS one 11 (4), e0153623, 2016 | 13 | 2016 |
Mitotic-dependent phosphorylation of leukemia-associated RhoGEF (LARG) by Cdk1 MC Helms, E Grabocka, MK Martz, CC Fischer, N Suzuki, ... Cellular signalling 28 (1), 43-52, 2016 | 11 | 2016 |
Stress granules and hormetic adaptation of cancer A Redding, E Grabocka Trends in Cancer 9 (12), 995-1005, 2023 | 9 | 2023 |
RAS-mediated tumor stress adaptation and the targeting opportunities it presents A Redding, AE Aplin, E Grabocka Disease Models & Mechanisms 15 (2), dmm049280, 2022 | 8 | 2022 |
Evaluating stress granules in pancreatic cancer in vitro and in vivo E Sim, E Irollo, E Grabocka Pancreatic Cancer: Methods and Protocols, 183-195, 2019 | 8 | 2019 |
A phase Ib study combining irinotecan with AZD1775, a selective WEE 1 kinase inhibitor, in RAS/RAF mutated metastatic colorectal cancer patients who progressed on first line … DJ Cohen, E Grabocka, D Bar-Sagi, R Godin, LP Leichman Journal of Clinical Oncology 35 (15_suppl), TPS3627-TPS3627, 2017 | 4 | 2017 |
Raf-1 and squamous cell carcinoma: Rok-ing the boat E Grabocka, D Bar-Sagi Cancer Cell 16 (2), 85-86, 2009 | 4 | 2009 |
A Splendid New Beginning at the End of a 40-Year Quest: The First KRASG12D Inhibitor in Pancreatic Cancer A Redding, E Grabocka Cancer Discovery 13 (2), 260-262, 2023 | 2 | 2023 |
Abstract A029: Unfolding the role of cell state on stress granule heterogeneity and function in KRAS-driven pancreatic cancer A Redding, G Fonteneau, E Grabocka Molecular Cancer Research 21 (5_Supplement), A029-A029, 2023 | | 2023 |