Structure of the human volume regulated anion channel JM Kefauver, K Saotome, AE Dubin, J Pallesen, CA Cottrell, SM Cahalan, ... Elife 7, e38461, 2018 | 114 | 2018 |
Long-primed germinal centres with enduring affinity maturation and clonal migration JH Lee, HJ Sutton, CA Cottrell, I Phung, G Ozorowski, LM Sewall, ... Nature 609 (7929), 998-1004, 2022 | 85 | 2022 |
HIV-1 envelope and MPER antibody structures in lipid assemblies K Rantalainen, ZT Berndsen, A Antanasijevic, T Schiffner, X Zhang, ... Cell Reports 31 (4), 2020 | 63 | 2020 |
Structures of the otopetrin proton channels Otop1 and Otop3 K Saotome, B Teng, CC Tsui, WH Lee, YH Tu, JP Kaplan, MSP Sansom, ... Nature structural & molecular biology 26 (6), 518-525, 2019 | 49 | 2019 |
Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike R Derking, JD Allen, CA Cottrell, K Sliepen, GE Seabright, WH Lee, ... Cell reports 35 (1), 2021 | 37 | 2021 |
Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques W He, M Yuan, S Callaghan, R Musharrafieh, G Song, M Silva, N Beutler, ... Science translational medicine 14 (657), eabl9605, 2022 | 24 | 2022 |
Developability assessment of physicochemical properties and stability profiles of HIV-1 BG505 SOSIP. 664 and BG505 SOSIP. v4. 1-GT1. 1 gp140 envelope glycoprotein trimers as … N Whitaker, JM Hickey, K Kaur, J Xiong, N Sawant, A Cupo, WH Lee, ... Journal of pharmaceutical sciences 108 (7), 2264-2277, 2019 | 22 | 2019 |
Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle vaccine candidate K Sliepen, L Radić, J Capella-Pujol, Y Watanabe, I Zon, A Chumbe, ... Nature communications 13 (1), 7271, 2022 | 20 | 2022 |
Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1 S Jojoa-Cruz, K Saotome, CCA Tsui, WH Lee, MSP Sansom, SE Murthy, ... Nature communications 13 (1), 850, 2022 | 20 | 2022 |
Stabilization of the V2 loop improves the presentation of V2 loop–associated broadly neutralizing antibody epitopes on HIV-1 envelope trimers SW de Taeye, EP Go, K Sliepen, AT de la Peña, K Badal, ... Journal of Biological Chemistry 294 (14), 5616-5631, 2019 | 16 | 2019 |
Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions TG Caniels, M Medina-Ramírez, J Zhang, A Sarkar, S Kumar, ... Cell Reports Medicine 4 (4), 2023 | 11 | 2023 |
Long-lasting germinal center responses to a priming immunization with continuous proliferation and somatic mutation JH Lee, H Sutton, CA Cottrell, I Phung, G Ozorowski, LM Sewall, ... Biorxiv, 2021.12. 20.473537, 2021 | 11 | 2021 |
A clade C HIV-1 vaccine protects against heterologous SHIV infection by modulating IgG glycosylation and T helper response in macaques A Sahoo, AT Jones, N Cheedarla, S Gangadhara, V Roy, TM Styles, ... Science immunology 7 (73), eabl4102, 2022 | 8 | 2022 |
Murine monoclonal antibodies against the receptor binding domain of SARS-CoV-2 neutralize authentic wild-type SARS-CoV-2 as well as B. 1.1. 7 and B. 1.351 viruses and protect … F Amanat, S Strohmeier, WH Lee, S Bangaru, AB Ward, L Coughlan, ... MBio 12 (4), 10.1128/mbio. 01002-21, 2021 | 7 | 2021 |
Structure-guided changes at the V2 apex of HIV-1 clade C trimer enhance elicitation of autologous neutralizing and broad V1V2-scaffold antibodies A Sahoo, EA Hodge, CC LaBranche, TM Styles, X Shen, N Cheedarla, ... Cell reports 38 (9), 2022 | 6 | 2022 |
Antibodies from rabbits immunized with HIV-1 clade B SOSIP trimers can neutralize multiple clade B viruses by destabilizing the envelope glycoprotein MM van Haaren, LE McCoy, JL Torres, W Lee, CA Cottrell, JL Copps, ... Journal of virology 95 (17), 10.1128/jvi. 00094-21, 2021 | 6 | 2021 |
Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection GM Martin, JL Torres, T Pholcharee, D Oyen, Y Flores-Garcia, G Gibson, ... Nature communications 14 (1), 4546, 2023 | 5 | 2023 |
Fine-mapping the immunodominant antibody epitopes on consensus sequence-based HIV-1 envelope trimer vaccine candidates E Reiss, MM van Haaren, J van Schooten, MAF Claireaux, ... npj Vaccines 7 (1), 152, 2022 | 5 | 2022 |
Conjugation of a Toll‐Like Receptor Agonist to Glycans of an HIV Native‐Like Envelope Trimer Preserves Neutralization Epitopes Z Li, R Derking, WH Lee, GP Bosman, AB Ward, RW Sanders, GJ Boons Chembiochem 23 (16), e202200236, 2022 | 4 | 2022 |
Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer R Kumar, S Deshpande, LM Sewall, G Ozorowski, CA Cottrell, WH Lee, ... PLoS pathogens 17 (4), e1008977, 2021 | 4 | 2021 |