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Wen-Hsin Lee
Wen-Hsin Lee
Verified email at scripps.edu
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Cited by
Year
Structure of the human volume regulated anion channel
JM Kefauver, K Saotome, AE Dubin, J Pallesen, CA Cottrell, SM Cahalan, ...
Elife 7, e38461, 2018
1142018
Long-primed germinal centres with enduring affinity maturation and clonal migration
JH Lee, HJ Sutton, CA Cottrell, I Phung, G Ozorowski, LM Sewall, ...
Nature 609 (7929), 998-1004, 2022
852022
HIV-1 envelope and MPER antibody structures in lipid assemblies
K Rantalainen, ZT Berndsen, A Antanasijevic, T Schiffner, X Zhang, ...
Cell Reports 31 (4), 2020
632020
Structures of the otopetrin proton channels Otop1 and Otop3
K Saotome, B Teng, CC Tsui, WH Lee, YH Tu, JP Kaplan, MSP Sansom, ...
Nature structural & molecular biology 26 (6), 518-525, 2019
492019
Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike
R Derking, JD Allen, CA Cottrell, K Sliepen, GE Seabright, WH Lee, ...
Cell reports 35 (1), 2021
372021
Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques
W He, M Yuan, S Callaghan, R Musharrafieh, G Song, M Silva, N Beutler, ...
Science translational medicine 14 (657), eabl9605, 2022
242022
Developability assessment of physicochemical properties and stability profiles of HIV-1 BG505 SOSIP. 664 and BG505 SOSIP. v4. 1-GT1. 1 gp140 envelope glycoprotein trimers as …
N Whitaker, JM Hickey, K Kaur, J Xiong, N Sawant, A Cupo, WH Lee, ...
Journal of pharmaceutical sciences 108 (7), 2264-2277, 2019
222019
Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle vaccine candidate
K Sliepen, L Radić, J Capella-Pujol, Y Watanabe, I Zon, A Chumbe, ...
Nature communications 13 (1), 7271, 2022
202022
Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1
S Jojoa-Cruz, K Saotome, CCA Tsui, WH Lee, MSP Sansom, SE Murthy, ...
Nature communications 13 (1), 850, 2022
202022
Stabilization of the V2 loop improves the presentation of V2 loop–associated broadly neutralizing antibody epitopes on HIV-1 envelope trimers
SW de Taeye, EP Go, K Sliepen, AT de la Peña, K Badal, ...
Journal of Biological Chemistry 294 (14), 5616-5631, 2019
162019
Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions
TG Caniels, M Medina-Ramírez, J Zhang, A Sarkar, S Kumar, ...
Cell Reports Medicine 4 (4), 2023
112023
Long-lasting germinal center responses to a priming immunization with continuous proliferation and somatic mutation
JH Lee, H Sutton, CA Cottrell, I Phung, G Ozorowski, LM Sewall, ...
Biorxiv, 2021.12. 20.473537, 2021
112021
A clade C HIV-1 vaccine protects against heterologous SHIV infection by modulating IgG glycosylation and T helper response in macaques
A Sahoo, AT Jones, N Cheedarla, S Gangadhara, V Roy, TM Styles, ...
Science immunology 7 (73), eabl4102, 2022
82022
Murine monoclonal antibodies against the receptor binding domain of SARS-CoV-2 neutralize authentic wild-type SARS-CoV-2 as well as B. 1.1. 7 and B. 1.351 viruses and protect …
F Amanat, S Strohmeier, WH Lee, S Bangaru, AB Ward, L Coughlan, ...
MBio 12 (4), 10.1128/mbio. 01002-21, 2021
72021
Structure-guided changes at the V2 apex of HIV-1 clade C trimer enhance elicitation of autologous neutralizing and broad V1V2-scaffold antibodies
A Sahoo, EA Hodge, CC LaBranche, TM Styles, X Shen, N Cheedarla, ...
Cell reports 38 (9), 2022
62022
Antibodies from rabbits immunized with HIV-1 clade B SOSIP trimers can neutralize multiple clade B viruses by destabilizing the envelope glycoprotein
MM van Haaren, LE McCoy, JL Torres, W Lee, CA Cottrell, JL Copps, ...
Journal of virology 95 (17), 10.1128/jvi. 00094-21, 2021
62021
Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection
GM Martin, JL Torres, T Pholcharee, D Oyen, Y Flores-Garcia, G Gibson, ...
Nature communications 14 (1), 4546, 2023
52023
Fine-mapping the immunodominant antibody epitopes on consensus sequence-based HIV-1 envelope trimer vaccine candidates
E Reiss, MM van Haaren, J van Schooten, MAF Claireaux, ...
npj Vaccines 7 (1), 152, 2022
52022
Conjugation of a Toll‐Like Receptor Agonist to Glycans of an HIV Native‐Like Envelope Trimer Preserves Neutralization Epitopes
Z Li, R Derking, WH Lee, GP Bosman, AB Ward, RW Sanders, GJ Boons
Chembiochem 23 (16), e202200236, 2022
42022
Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer
R Kumar, S Deshpande, LM Sewall, G Ozorowski, CA Cottrell, WH Lee, ...
PLoS pathogens 17 (4), e1008977, 2021
42021
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