The Major Risk Factors for Alzheimer’s Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques CS Frigerio, L Wolfs, N Fattorelli, N Thrupp, I Voytyuk, I Schmidt, ... Cell Reports 27 (4), 1293-1306. e6, 2019 | 607 | 2019 |
Single-Nucleus RNA-Seq Is Not Suitable for Detection of Microglial Activation Genes in Humans N Thrupp, CS Frigerio, L Wolfs, NG Skene, N Fattorelli, S Poovathingal, ... Cell Reports 32 (13), 108189, 2020 | 219 | 2020 |
Novel Alzheimer risk genes determine the microglia response to amyloid‐β but not to TAU pathology A Sierksma, A Lu, R Mancuso, N Fattorelli, N Thrupp, E Salta, J Zoco, ... EMBO Molecular Medicine, 2019 | 216 | 2019 |
Stem-cell-derived human microglia transplanted in mouse brain to study human disease R Mancuso, J Van Den Daele, N Fattorelli, L Wolfs, S Balusu, O Burton, ... Nature neuroscience 22 (12), 2111-2116, 2019 | 199 | 2019 |
Stem-cell-derived human microglia transplanted into mouse brain to study human disease N Fattorelli, A Martinez-Muriana, L Wolfs, I Geric, B De Strooper, ... Nature Protocols 16 (2), 1013-1033, 2021 | 56 | 2021 |
A multi-pronged human microglia response to Alzheimer's disease Aβ pathology R Mancuso, N Fattorelli, A Martinez-Muriana, E Davis, L Wolfs, ... bioRxiv, 2022 | 14 | 2022 |
Stem cell derived human microglia transplanted in mouse brain to study genetic risk of Alzheimer's Disease R Mancuso, J Van Den Daele, N Fattorelli, L Wolfs, S Balusu, O Burton, ... bioRxiv, 562561, 2019 | 4 | 2019 |
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease-related amyloid-β pathology R Mancuso, N Fattorelli, A Martinez-Muriana, E Davis, L Wolfs, ... Nature Neuroscience, 1-15, 2024 | 3 | 2024 |
The γ-secretase substrate proteome and its role in cell signaling regulation P Hou, M Zielonka, L Serneels, A Martinez-Muriana, N Fattorelli, L Wolfs, ... Molecular Cell 83 (22), 4106-4122. e10, 2023 | 3 | 2023 |
A xenograft model to study human microglia genetics, development and disease N Fattorelli | | 2024 |