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Paul Titchenell
Paul Titchenell
Assistant Professor, University of Pennsylvania
Verified email at mail.med.upenn.edu
Title
Cited by
Cited by
Year
Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes
RJ Perry, JPG Camporez, R Kursawe, PM Titchenell, D Zhang, CJ Perry, ...
Cell 160 (4), 745-758, 2015
5522015
Unraveling the regulation of hepatic metabolism by insulin
PM Titchenell, MA Lazar, MJ Birnbaum
Trends in Endocrinology & Metabolism 28 (7), 497-505, 2017
2202017
Direct hepatocyte insulin signaling is required for lipogenesis but is dispensable for the suppression of glucose production
PM Titchenell, WJ Quinn, M Lu, Q Chu, W Lu, C Li, H Chen, BR Monks, ...
Cell metabolism 23 (6), 1154-1166, 2016
2092016
Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate
S Zhao, C Jang, J Liu, K Uehara, M Gilbert, L Izzo, X Zeng, S Trefely, ...
Nature 579 (7800), 586-591, 2020
1852020
Hepatic insulin signalling is dispensable for suppression of glucose output by insulin in vivo
PM Titchenell, Q Chu, BR Monks, MJ Birnbaum
Nature communications 6 (1), 1-9, 2015
1452015
The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver
K Patel, M Foretz, A Marion, DG Campbell, R Gourlay, N Boudaba, ...
Nature communications 5 (1), 1-16, 2014
1392014
Resolving the paradox of hepatic insulin resistance
D Santoleri, PM Titchenell
Cellular and molecular gastroenterology and hepatology 7 (2), 447-456, 2019
982019
Novel atypical PKC inhibitors prevent vascular endothelial growth factor-induced blood–retinal barrier dysfunction
PM Titchenell, CM Lin, JM Keil, JM Sundstrom, CD Smith, DA Antonetti
Biochemical Journal 446 (3), 455-467, 2012
742012
The role of skeletal muscle Akt in the regulation of muscle mass and glucose homeostasis
N Jaiswal, MG Gavin, WJ Quinn III, TS Luongo, RG Gelfer, JA Baur, ...
Molecular metabolism 28, 1-13, 2019
702019
Physiological suppression of lipotoxic liver damage by complementary actions of HDAC3 and SCAP/SREBP
R Papazyan, Z Sun, YH Kim, PM Titchenell, DA Hill, W Lu, M Damle, ...
Cell metabolism 24 (6), 863-874, 2016
592016
Using the past to inform the future: anti-VEGF therapy as a road map to develop novel therapies for diabetic retinopathy
PM Titchenell, DA Antonetti
Diabetes 62 (6), 1808-1815, 2013
582013
SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeeding
H Jang, GY Lee, CP Selby, G Lee, YG Jeon, JH Lee, KKY Cheng, ...
Nature communications 7 (1), 1-14, 2016
572016
mTORC1 stimulates phosphatidylcholine synthesis to promote triglyceride secretion
WJ Quinn, M Wan, SV Shewale, R Gelfer, DJ Rader, MJ Birnbaum, ...
The Journal of clinical investigation 127 (11), 4207-4215, 2017
452017
Shared PPARα/γ target genes regulate brown adipocyte thermogenic function
Y Shen, Y Su, FJ Silva, AH Weller, J Sostre-Colón, PM Titchenell, ...
Cell Reports 30 (9), 3079-3091. e5, 2020
202020
Early B cell factor activity controls developmental and adaptive thermogenic gene programming in adipocytes
AR Angueira, SN Shapira, J Ishibashi, S Sampat, J Sostre-Colón, ...
Cell reports 30 (9), 2869-2878. e4, 2020
182020
MondoA drives muscle lipid accumulation and insulin resistance
B Ahn, S Wan, N Jaiswal, RB Vega, DE Ayer, PM Titchenell, X Han, ...
JCI insight 4 (15), 2019
162019
Inhibition of atypical protein kinase C reduces inflammation-induced retinal vascular permeability
C Lin, PM Titchenell, JM Keil, A Garcia-Ocaña, MT Bolinger, SF Abcouwer, ...
The American journal of pathology 188 (10), 2392-2405, 2018
162018
Synthesis and structure–activity relationships of 2-amino-3-carboxy-4-phenylthiophenes as novel atypical protein kinase C inhibitors
PM Titchenell, HDH Showalter, JF Pons, AJ Barber, Y Jin, DA Antonetti
Bioorganic & medicinal chemistry letters 23 (10), 3034-3038, 2013
162013
siRNA-mediated knockdown of h-caldesmon in vascular smooth muscle
EM Smolock, DM Trappanese, S Chang, T Wang, P Titchenell, ...
American Journal of Physiology-Heart and Circulatory Physiology 297 (5 …, 2009
152009
The Polycomb protein, Bmi1, regulates insulin sensitivity
CE Cannon, PM Titchenell, DN Groff, A El Ouaamari, RN Kulkarni, ...
Molecular metabolism 3 (8), 794-802, 2014
122014
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