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Kate Saville
Kate Saville
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Cited by
Cited by
Year
Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis
CA Koczor, KM Saville, JF Andrews, J Clark, Q Fang, J Li, ...
Cell reports 37 (5), 2021
402021
NAD+-mediated regulation of mammalian base excision repair
KM Saville, J Clark, A Wilk, GD Rogers, JF Andrews, CA Koczor, ...
DNA repair 93, 102930, 2020
292020
NAD+ bioavailability mediates PARG inhibition-induced replication arrest, intra S-phase checkpoint and apoptosis in glioma stem cells
J Li, K M. Saville, M Ibrahim, X Zeng, S McClellan, A Angajala, A Beiser, ...
NAR cancer 3 (4), zcab044, 2021
142021
Overcoming Temozolomide Resistance in Glioblastoma via Enhanced NAD+ Bioavailability and Inhibition of Poly-ADP-Ribose Glycohydrolase
J Li, CA Koczor, KM Saville, F Hayat, A Beiser, S McClellan, ME Migaud, ...
Cancers 14 (15), 3572, 2022
82022
Live cell detection of poly (ADP-ribose) for use in genetic and genotoxic compound screens
CA Koczor, AJ Haider, KM Saville, J Li, JF Andrews, AV Beiser, RW Sobol
Cancers 14 (15), 3676, 2022
52022
Quantitative analysis of nuclear poly (ADP-ribose) dynamics in response to laser-induced DNA damage
CA Koczor, KM Saville, RQ Al-Rahahleh, JF Andrews, J Li, RW Sobol
Poly (ADP-Ribose) Polymerase: Methods and Protocols, 43-59, 2022
12022
Oncometabolite 2-hydroxyglutarate suppresses basal protein levels of DNA polymerase beta that enhances alkylating agent and PARG inhibition induced cytotoxicity
KM Saville, RQ Al-Rahahleh, AH Siddiqui, ME Andrews, WP Roos, ...
DNA Repair, 103700, 2024
2024
Overexpression of the WWE domain of RNF146 modulates poly-(ADP)-ribose dynamics at sites of DNA damage
RQ Al-Rahahleh, KM Saville, JF Andrews, Z Wu, CA Koczor, RW Sobol
bioRxiv, 2023.12. 29.573650, 2023
2023
The Role of PARP1 and NAD+ Bioavailability in Base Excision and Single-Strand Break Repair
KM Saville
University of South Alabama, 2022
2022
Sensitivity of melanoma cells to a novel class of Ras inhibitors
KM Saville, K Lee, TE Mattox, X Chen, J Valiyaveettil, K Berry, ...
Cancer Research 77 (13_Supplement), 5166-5166, 2017
2017
Novel Ras inhibitor DC070-547 potently and selectively blocks Ras-RBD binding, EGFR binding to Ras signaling complex, EGFR activation of Ras signaling, and growth of Ras-driven …
B Zhu, X Chen, J Valiyaveettil, J Canzoneri, K Lee, K Saville, K Berry, ...
Cancer Research 77 (13_Supplement), 4972-4972, 2017
2017
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