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Junfeng Huo
Junfeng Huo
Verified email at hust.edu.cn
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Year
Rational design and synthesis of novel dual PROTACs for simultaneous degradation of EGFR and PARP
M Zheng, J Huo, X Gu, Y Wang, C Wu, Q Zhang, W Wang, Y Liu, Y Liu, ...
Journal of Medicinal Chemistry 64 (11), 7839-7852, 2021
1112021
EMT and cancer cell stemness associated with chemotherapeutic resistance in esophageal cancer
X Liu, M He, L Li, X Wang, S Han, J Zhao, Y Dong, M Ahmad, L Li, ...
Frontiers in Oncology 11, 672222, 2021
302021
Structure-Based Design, Synthesis, and Biological Evaluation of New Triazolo[1,5-a]Pyrimidine Derivatives as Highly Potent and Orally Active ABCB1 Modulators
S Wang, SQ Wang, QX Teng, L Yang, ZN Lei, XH Yuan, JF Huo, XB Chen, ...
Journal of Medicinal Chemistry 63 (24), 15979-15996, 2020
292020
Design, synthesis, and evaluation of PD-L1 degraders to enhance T cell killing activity against melanoma
Y Liu, M Zheng, Z Ma, Y Zhou, J Huo, W Zhang, Y Liu, Y Guo, X Zhou, H Li, ...
Chinese Chemical Letters 34 (5), 107762, 2023
222023
Discovery of chalcone-modified estradiol analogs as antitumour agents that Inhibit tumour angiogenesis and epithelial to mesenchymal transition
C Wang, L Li, D Fu, T Qin, Y Ran, F Xu, X Du, H Gao, S Sun, T Yang, ...
European Journal of Medicinal Chemistry 176, 135-148, 2019
202019
SIRT1 expression regulates the transformation of resistant esophageal cancer cells via the epithelial-mesenchymal transition
T Qin, W Liu, J Huo, L Li, X Zhang, X Shi, J Zhou, C Wang
Biomedicine & Pharmacotherapy 103, 308-316, 2018
172018
Luteolin combined with low‐dose paclitaxel synergistically inhibits epithelial–mesenchymal transition and induces cell apoptosis on esophageal carcinoma in vitro and in vivo
T Qin, J Zhao, X Liu, L Li, X Zhang, X Shi, Y Ke, W Liu, J Huo, Y Dong, ...
Phytotherapy Research 35 (11), 6228-6240, 2021
162021
Synthesis and in vitro biological evaluation of novel derivatives of Flexicaulin A condensation with amino acid trifluoroacetate
Y Ke, TX Hu, JF Huo, JK Yan, JY Wang, RH Yang, H Xie, Y Liu, N Wang, ...
European Journal of Medicinal Chemistry 182, 111645, 2019
82019
Selective anticancer activity of the novel steroidal dihydropyridine spirooxindoles against human esophageal EC109 cells
X Shi, T Qin, W Liu, X Zhang, L Li, J Huo, K Zhou, D Yang, Y Zhang, ...
Biomedicine & Pharmacotherapy 96, 1186-1192, 2017
52017
Synthesis and in vitro and in vivo biological evaluation of novel derivatives of flexicaulin A as antiproliferative agents
JF Huo, TX Hu, YL Dong, JZ Zhao, XJ Liu, LL Li, XY Zhang, YF Li, HM Liu, ...
European Journal of Medicinal Chemistry 208, 112789, 2020
42020
Distinguishing G-Quadruplexes Stabilizer and Chaperone for c-MYC Promoter G-Quadruplexes through Single-Molecule Manipulation
Y Zhang, Y Cheng, Q Luo, T Wu, J Huo, M Yin, H Peng, Y Xiao, Q Tong, ...
Journal of the American Chemical Society, 2024
12024
Discovery of linear unnatural peptides as potent mutant isocitrate dehydrogenase 1 inhibitors by Ugi reaction
X Zhou, M Zheng, N Zhao, Y Hu, K Yang, J Huo, G Liu, J Huang, L Chen, ...
Bioorganic Chemistry 119, 105569, 2022
12022
The mechanism by which SIRT1 regulates autophagy and EMT in drug-resistant oesophageal cancer cells
X Zhang, Y Dong, W Li, M He, Y Shi, S Han, L Li, J Zhao, L Li, J Huo, X Liu, ...
Life Sciences, 122530, 2024
2024
Force-Enhanced Sensitive Detection of New DNA-Interactive Agents from Microorganisms at the Single-Molecule Level
T Liu, T Cai, J Huo, H Liu, A Li, M Yin, Y Mei, Y Zhou, S Fan, Y Lu, L Wan, ...
bioRxiv, 2024.04. 22.590585, 2024
2024
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