Polyunsaturated fatty acid analogs act antiarrhythmically on the cardiac IKs channel SI Liin, M Silverå Ejneby, R Barro-Soria, MA Skarsfeldt, JE Larsson, ... Proceedings of the National Academy of Sciences 112 (18), 5714-5719, 2015 | 89 | 2015 |
Fatty acid analogue N-arachidonoyl taurine restores function of IKs channels with diverse long QT mutations SI Liin, JE Larsson, R Barro-Soria, BH Bentzen, HP Larsson Elife 5, e20272, 2016 | 31 | 2016 |
Identification of PUFA interaction sites on the cardiac potassium channel KCNQ1 S Yazdi, J Nikesjö, W Miranda, V Corradi, DP Tieleman, SY Noskov, ... Journal of General Physiology 153 (6), 2021 | 27 | 2021 |
KCNE1 tunes the sensitivity of KV7.1 to polyunsaturated fatty acids by moving turret residues close to the binding site JE Larsson, HP Larsson, SI Liin Elife 7, e37257, 2018 | 27 | 2018 |
Polyunsaturated fatty acids as modulators of KV7 channels JE Larsson, DJA Frampton, SI Liin Frontiers in physiology 11, 543837, 2020 | 17 | 2020 |
Combining endocannabinoids with retigabine for enhanced M-channel effect and improved KV7 subtype selectivity JE Larsson, U Karlsson, X Wu, SI Liin Journal of General Physiology 152 (8), e202012576, 2020 | 17 | 2020 |
Biaryl sulfonamide motifs up-or down-regulate ion channel activity by activating voltage sensors SI Liin, PE Lund, JE Larsson, J Brask, B Wallner, F Elinder Journal of General Physiology 150 (8), 1215-1230, 2018 | 9 | 2018 |
Subtype-specific responses of hKv7. 4 and hKv7. 5 channels to polyunsaturated fatty acids reveal an unconventional modulatory site and mechanism DJA Frampton, K Choudhury, J Nikesjö, L Delemotte, SI Liin Elife 11, e77672, 2022 | 6 | 2022 |
Endocannabinoids enhance hKV7. 1/KCNE1 channel function and shorten the cardiac action potential and QT interval I Hiniesto-Iñigo, LM Castro-Gonzalez, V Corradi, MA Skarsfeldt, S Yazdi, ... EBioMedicine 89, 2023 | 3 | 2023 |
Endocannabinoid-like compounds as modulators of the cardiac kv7. 1/KCNE1 channel IH Iñigo, S Lundholm, JE Nikesjö, SI Liin Biophysical Journal 121 (3), 240a-241a, 2022 | 1 | 2022 |
N-Arachidonoyl Taurine Rescues Diverse Long QT Syndrome-Associated Mutations in the Cardiac I← Ks Channel SI Liin, JE Larsson, R Barro-Soria, MA Skarsfeldt, BH Bentzen, ... Biophysical Journal 110 (3), 185a-186a, 2016 | 1 | 2016 |
KCNE1 Modulates the Sensitivity of Kv7. 1 to Polyunsaturated Fatty Acids SI Liin, N Schmitt, J Larsson, FS Härlin, BH Bentzen, HP Larsson, ... Biophysical Journal 106 (2), 143a, 2014 | 1 | 2014 |
Long-QT mutations in KCNE1 modulate the 17β-estradiol response of Kv7. 1/KCNE1 LM Erlandsdotter, L Giammarino, A Halili, J Nikesjö, H Gréen, ... Science Advances 9 (11), eade7109, 2023 | | 2023 |
Subtype specific responses in hKv7. 4 and hKv7. 5 channels to polyunsaturated fatty acids DJA Frampton, J Nikesjö, SI Liin bioRxiv, 2021.08. 20.457075, 2021 | | 2021 |
Molecular mechanisms of modulation of KV7 channels by polyunsaturated fatty acids and their analogues J Larsson Linköping University Electronic Press, 2020 | | 2020 |
Identification of PUFA Interaction Sites on a Cardiac Potassium Channel S Yazdi, JE Larsson, WE Miranda, V Corradi, PD Tieleman, SY Noskov, ... Biophysical Journal 118 (3), 168a, 2020 | | 2020 |
Probing the Molecular Basis of Opposing PUFA Effects on KV7 Channels DJA Frampton, LC Abrahamsson, JE Larsson, SI Liin Biophysical Journal 118 (3), 109a, 2020 | | 2020 |
Endocannabinoids Facilitate the Opening of the M-Channel JE Larsson, L Sara Biophysical Journal 116 (3), 544a, 2019 | | 2019 |
Identification of Residues Important for the PUFA Sensitivity of IKs JE Larsson, HP Larsson, SI Liin Biophysical Journal 110 (3), 277a, 2016 | | 2016 |
Polyunsaturated Fatty Acid Analogues Act Anti-Arrhythmic on the Cardiac IKs Channel SI Liin, MS Ejneby, R Barro-Soria, JE Larsson, FS Härlin, BH Bentzen, ... Biophysical Journal 108 (2), 275a, 2015 | | 2015 |