| The proline-rich domain of tau plays a role in interactions with actin HJ He, XS Wang, R Pan, DL Wang, MN Liu, RQ He Bmc Cell Biology 10 (81), 2009 | 155 | 2009 |
| Ischemic neurons activate astrocytes to disrupt endothelial barrier via increasing VEGF expression YN Li, R Pan, XJ Qin, WL Yang, Z Qi, W Liu, KJ Liu Journal of neurochemistry 129 (1), 120-129, 2014 | 130 | 2014 |
| A fluorescent probe capable of detecting H 2 S at submicromolar concentrations in cells W Xuan, R Pan, Y Cao, K Liu, W Wang Chemical communications 48 (86), 10669-10671, 2012 | 125 | 2012 |
| Chelating intracellularly accumulated zinc decreased ischemic brain injury through reducing neuronal apoptotic death Y Zhao, R Pan, S Li, Y Luo, F Yan, J Yin, Z Qi, Y Yan, X Ji, KJ Liu Stroke 45 (4), 1139-1147, 2014 | 73 | 2014 |
| Reaction-based “off–on” fluorescent probe enabling detection of endogenous labile Fe2+ and imaging of Zn2+-induced Fe2+ flux in living cells and elevated Fe2+ in ischemic stroke W Xuan, R Pan, Y Wei, Y Cao, H Li, FS Liang, KJ Liu, W Wang Bioconjugate chemistry 27 (2), 302-308, 2016 | 71 | 2016 |
| Normobaric hyperoxia reduces blood occludin fragments in rats and patients with acute ischemic stroke S Shi, Z Qi, Q Ma, R Pan, GS Timmins, Y Zhao, W Shi, Y Zhang, X Ji, ... Stroke 48 (10), 2848-2854, 2017 | 65 | 2017 |
| Hyperphosphorylation results in tau dysfunction in DNA folding and protection Y Lu, HJ He, J Zhou, JY Miao, J Lu, YG He, R Pan, Y Wei, Y Liu, RQ He Journal of Alzheimer's Disease 37 (3), 551-563, 2013 | 58 | 2013 |
| Glycosylated trypsin-like proteases from earthworm Eisenia fetida JX Wu, XY Zhao, R Pan, RQ He International Journal of Biological Macromolecules 40 (5), 399-406, 2007 | 56 | 2007 |
| Zinc contributes to acute cerebral ischemia-induced blood–brain barrier disruption Z Qi, J Liang, R Pan, W Dong, J Shen, Y Yang, Y Zhao, W Shi, Y Luo, X Ji, ... Neurobiology of disease 95, 12-21, 2016 | 53 | 2016 |
| Earthworm protease R Pan, ZJ Zhang, RQ He Applied and Environmental Soil Science 2010, 2010 | 48 | 2010 |
| Eisenia fetida Protease-III-1 Functions in Both Fibrinolysis and Fibrogenesis J Zhao, R Pan, J He, Y Liu, DF Li, RQ He BioMed Research International 2007, 2007 | 46 | 2007 |
| Zinc promotes the death of hypoxic astrocytes by upregulating hypoxia‐induced hypoxia‐inducible factor‐1alpha expression via poly (ADP‐ribose) polymerase‐1 R Pan, C Chen, WL Liu, KJ Liu CNS neuroscience & therapeutics 19 (7), 511-520, 2013 | 41 | 2013 |
| In situ localization and substrate specificity of earthworm protease-II and protease-III-1 from Eisenia fetida J Zhao, R Xiao, J He, R Pan, R Fan, C Wu, X Liu, Y Liu, RQ He International journal of biological macromolecules 40 (2), 67-75, 2007 | 38 | 2007 |
| Autophagy mediates astrocyte death during zinc-potentiated ischemia–reperfusion injury R Pan, GS Timmins, W Liu, KJ Liu Biological trace element research 166, 89-95, 2015 | 32 | 2015 |
| Normobaric hyperoxia extends neuro-and vaso-protection of N-acetylcysteine in transient focal ischemia Y Liu, WC Liu, Y Sun, X Shen, X Wang, H Shu, R Pan, CF Liu, W Liu, ... Molecular Neurobiology 54 (5), 3418-3427, 2017 | 28 | 2017 |
| Substrate-induced changes in protease active site conformation impact on subsequent reactions with substrates R Pan, XJ Zhang, ZJ Zhang, Y Zhou, WX Tian, RQ He Journal of biological chemistry 285 (30), 22950-22956, 2010 | 25 | 2010 |
| Formaldehyde-mediated hyperphosphorylation disturbs the interaction between Tau protein and DNA J Lu, JY Miao, R Pan, RQ He Progress in Biochemistry and Biophysics 38 (12), 1113-1120, 2011 | 19 | 2011 |
| An earthworm protease cleaving serum fibronectin and decreasing HBeAg in HepG2. 2.15 cells XQ Wang, L Chen, R Pan, J Zhao, Y Liu, RQ He BMC biochemistry 9, 1-14, 2008 | 15 | 2008 |
| Extended normobaric hyperoxia therapy yields greater neuroprotection for focal transient ischemia-reperfusion in rats. Z Yuan, R Pan, W Liu, KJ Liu Med Gas Res., 2014 | 14 | 2014 |
| An enzyme from the earthworm Eisenia fetida is not only a protease but also a deoxyribonuclease R Pan, Y Zhou, HJ He, RQ He Biochemical and Biophysical Research Communications 407 (1), 113-117, 2011 | 12 | 2011 |
