Leo Gerweck
Leo Gerweck
Massachusetts General Hospital
Verified email at mgh.harvard.edu
Cited by
Cited by
Cellular responses to combinations of hyperthermia and radiation
WC Dewey, LE Hopwood, SA Sapareto, LE Gerweck
Radiology 123 (2), 463-474, 1977
Cellular pH gradient in tumor versus normal tissue: potential exploitation for the treatment of cancer
LE Gerweck, K Seetharaman
Cancer research 56 (6), 1194-1198, 1996
Relative biological effectiveness (RBE) values for proton beam therapy
H Paganetti, A Niemierko, M Ancukiewicz, LE Gerweck, M Goitein, ...
International Journal of Radiation Oncology* Biology* Physics 53 (2), 407-421, 2002
Modification of cell lethality at elevated temperatures the pH effect
LE Gerweck
Radiation Research 70 (1), 224-235, 1977
The multidrug resistance (mdr1) gene product functions as an ATP channel
EH Abraham, AG Prat, L Gerweck, T Seneveratne, RJ Arceci, R Kramer, ...
Proceedings of the National Academy of Sciences 90 (1), 312-316, 1993
Tumor pH controls the in vivo efficacy of weak acid and base chemotherapeutics
LE Gerweck, S Vijayappa, S Kozin
Molecular cancer therapeutics 5 (5), 1275-1279, 2006
Proton vs carbon ion beams in the definitive radiation treatment of cancer patients
H Suit, T DeLaney, S Goldberg, H Paganetti, B Clasie, L Gerweck, ...
Radiotherapy and Oncology 95 (1), 3-22, 2010
Relative biological effectiveness of proton beams in clinical therapy
LE Gerweck, SV Kozin
Radiotherapy and oncology 50 (2), 135-142, 1999
Effect of heat and radiation on synchronous Chinese hamster cells: Killing and repair
LE Gerweck, EL Gillette, WC Dewey
Radiation Research 64 (3), 611-623, 1975
Response of cells to hyperthermia under acute and chronic hypoxic conditions
LE Gerweck, TG Nygaard, M Burlett
Cancer research 39 (3), 966-972, 1979
Killing of Chinese hamster cells in vitro by heating under hypoxic or aerobic conditions
LE Gerweck, EL Gillette, WC Dewey
European Journal of Cancer (1965) 10 (10), 691-693, 1974
Potential for hyperthermia and radiation therapy
HD Suit, LE Gerweck
Cancer research 39 (6 Part 2), 2290-2298, 1979
Tumor pH: implications for treatment and novel drug design
LE Gerweck
Seminars in radiation oncology 8 (3), 176-182, 1998
Perivascular nitric oxide gradients normalize tumor vasculature
S Kashiwagi, K Tsukada, L Xu, J Miyazaki, SV Kozin, JA Tyrrell, ...
Nature medicine 14 (3), 255-257, 2008
Hyperthermia in cancer therapy: the biological basis and unresolved questions
LE Gerweck
Cancer research 45 (8), 3408-3414, 1985
Enhancement of mammalian cell sensitivity to hyperthermia by pH alteration
L Gerweck, E Rottinger
Radiation Research 67 (3), 508-511, 1976
The cell transmembrane pH gradient in tumors enhances cytotoxicity of specific weak acid chemotherapeutics
SV Kozin, P Shkarin, LE Gerweck
Cancer research 61 (12), 4740-4743, 2001
Tumor size dependent changes in a murine fibrosarcoma: Use of in vivo31P NMR for non-invasive evaluation of tumor metabolic status
PG Okunieff, JA Koutcher, L Gerweck, E Mcfarland, B Hitzig, M Urano, ...
International Journal of Radiation Oncology* Biology* Physics 12 (5), 793-799, 1986
Iodine-124-labeled iodo-azomycin-galactoside imaging of tumor hypoxia in mice with serial microPET scanning
P Zanzonico, J O’Donoghue, JD Chapman, R Schneider, S Cai, S Larson, ...
European Journal of Nuclear Medicine and Molecular Imaging 31 (1), 117-128, 2004
Biological and clinical aspects of hyperthermia in cancer therapy
JR Oleson, SK Calderwood, CT Coughlin, MW Dewhirst, LE Gerweck, ...
American Journal of Clinical Oncology 11 (3), 368-380, 1988
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