Leo Gerweck
Leo Gerweck
Massachusetts General Hospital
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Cellular pH Gradient in Tumor versus Normal Tissue: Potential Exploitation for the Treatment of Cancer
LE Gerweck, K Seetharaman
Cancer research 56 (6), 1194-1198, 1996
Cellular responses to combinations of hyperthermia and radiation
WC Dewey, LE Hopwood, SA Sapareto, LE Gerweck
Radiology 123 (2), 463-474, 1977
Relative biological effectiveness (RBE) values for proton beam therapy
H Paganetti, A Niemierko, M Ancukiewicz, LE Gerweck, M Goitein, ...
International Journal of Radiation Oncology* Biology* Physics 53 (2), 407-421, 2002
The multidrug resistance (mdr1) gene product functions as an ATP channel.
EH Abraham, AG Prat, L Gerweck, T Seneveratne, RJ Arceci, R Kramer, ...
Proceedings of the National Academy of Sciences 90 (1), 312-316, 1993
Modification of cell lethality at elevated temperatures the pH effect
LE Gerweck
Radiation Research 70 (1), 224-235, 1977
Tumor pH controls the in vivo efficacy of weak acid and base chemotherapeutics
LE Gerweck, S Vijayappa, S Kozin
Molecular cancer therapeutics 5 (5), 1275-1279, 2006
Proton vs carbon ion beams in the definitive radiation treatment of cancer patients
H Suit, T DeLaney, S Goldberg, H Paganetti, B Clasie, L Gerweck, ...
Radiotherapy and Oncology 95 (1), 3-22, 2010
Relative biological effectiveness of proton beams in clinical therapy
LE Gerweck, SV Kozin
Radiotherapy and oncology 50 (2), 135-142, 1999
Effect of heat and radiation on synchronous Chinese hamster cells: Killing and repair
LE Gerweck, EL Gillette, WC Dewey
Radiation Research 64 (3), 611-623, 1975
Potential for hyperthermia and radiation therapy
HD Suit, LE Gerweck
Cancer research 39 (6_Part_2), 2290-2298, 1979
Response of cells to hyperthermia under acute and chronic hypoxic conditions
LE Gerweck, TG Nygaard, M Burlett
Cancer research 39 (3), 966-972, 1979
Tumor pH: implications for treatment and novel drug design
LE Gerweck
Seminars in radiation oncology 8 (3), 176-182, 1998
Killing of Chinese hamster cells in vitro by heating under hypoxic or aerobic conditions
LE Gerweck, EL Gillette, WC Dewey
European Journal of Cancer (1965) 10 (10), 691-693, 1974
Perivascular nitric oxide gradients normalize tumor vasculature
S Kashiwagi, K Tsukada, L Xu, J Miyazaki, SV Kozin, JA Tyrrell, ...
Nature medicine 14 (3), 255-257, 2008
Hyperthermia in cancer therapy: the biological basis and unresolved questions
LE Gerweck
Cancer research 45 (8), 3408-3414, 1985
Enhancement of mammalian cell sensitivity to hyperthermia by pH alteration
L Gerweck, E Rottinger
Radiation Research 67 (3), 508-511, 1976
Dose-rate effects in external beam radiotherapy redux
CC Ling, LE Gerweck, M Zaider, E Yorke
Radiotherapy and Oncology 95 (3), 261-268, 2010
The cell transmembrane pH gradient in tumors enhances cytotoxicity of specific weak acid chemotherapeutics
SV Kozin, P Shkarin, LE Gerweck
Cancer research 61 (12), 4740-4743, 2001
Tumor cell radiosensitivity is a major determinant of tumor response to radiation
LE Gerweck, S Vijayappa, A Kurimasa, K Ogawa, DJ Chen
Cancer research 66 (17), 8352-8355, 2006
Tumor size dependent changes in a murine fibrosarcoma: Use of in vivo31P NMR for non-invasive evaluation of tumor metabolic status
PG Okunieff, JA Koutcher, L Gerweck, E Mcfarland, B Hitzig, M Urano, ...
International Journal of Radiation Oncology* Biology* Physics 12 (5), 793-799, 1986
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