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Gizem Efe
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MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy
M Owyong, J Chou, RJE van den Bijgaart, N Kong, G Efe, C Maynard, ...
Life science alliance 2 (6), 2019
852019
Overcoming barriers of age to enhance efficacy of cancer immunotherapy: the clout of the extracellular matrix
M Owyong, G Efe, M Owyong, AJ Abbasi, V Sitarama, V Plaks
Frontiers in Cell and Developmental Biology 6, 19, 2018
252018
Cancer immunotherapy getting brainy: visualizing the distinctive CNS metastatic niche to illuminate therapeutic resistance
M Owyong, N Hosseini-Nassab, G Efe, A Honkala, RJE van den Bijgaart, ...
Drug Resistance Updates 33, 23-35, 2017
202017
Mutant p53 regulates Survivin to foster lung metastasis
Q Tang, G Efe, AM Chiarella, J Leung, M Chen, T Yamazoe, Z Su, ...
Genes & Development 35 (7-8), 528-541, 2021
192021
Rab11‐FIP1 mediates epithelial‐mesenchymal transition and invasion in esophageal cancer
Q Tang, A Lento, K Suzuki, G Efe, T Karakasheva, A Long, V Giroux, ...
EMBO reports 22 (2), e48351, 2021
152021
Standardized reporter systems for purification and imaging of human pluripotent stem cell-derived motor neurons and other cholinergic cells
A Garcia-Diaz, G Efe, K Kabra, A Patel, ER Lowry, NA Shneider, B Corneo, ...
Neuroscience 450, 48-56, 2020
112020
Key genetic determinants driving esophageal squamous cell carcinoma initiation and immune evasion
KP Ko, Y Huang, S Zhang, G Zou, B Kim, J Zhang, S Jun, C Martin, ...
Gastroenterology 165 (3), 613-628. e20, 2023
102023
Roles of estrogen receptor-alpha in mediating life span: the hypothalamic deregulation hypothesis
AM Gouw, G Efe, R Barakat, A Preecha, M Mehdizadeh, SA Garan, ...
Physiological genomics 49 (2), 88-95, 2017
102017
Tumor-derived CCL5 recruits cancer-associated fibroblasts and promotes tumor cell proliferation in esophageal squamous cell carcinoma
KJ Dunbar, TA Karakasheva, Q Tang, G Efe, EW Lin, M Harris, V Sahu, ...
Molecular Cancer Research 21 (7), 741-752, 2023
72023
p53 gain-of-function mutation induces metastasis via Brd4-dependent Csf-1 expression
G Efe, KJ Dunbar, K Sugiura, K Cunningham, S Carcamo, S Karaiskos, ...
Cancer Discovery 13 (12), 2632-2651, 2023
32023
Engineered hydrogel reveals contribution of matrix mechanics to esophageal adenocarcinoma and identifies matrix-activated therapeutic targets
R Cruz-Acuña, SW Kariuki, K Sugiura, S Karaiskos, EM Plaster, C Loebel, ...
The Journal of Clinical Investigation 133 (23), 2023
22023
Tumor Niche Network-Defined Subtypes Predict Immunotherapy Response of Esophageal Squamous Cell Cancer
KP Ko, S Zhang, Y Huang, B Kim, G Zou, S Jun, J Zhang, Y Zhao, ...
iScience, 2024
2024
Engineered hydrogel elucidates contributions of matrix mechanics to pathobiology of adenocarcinoma and identify matrix-activated therapeutic targets
R Cruz-Acuna, SW Kariuki, K Sugiura, S Karaiskos, EM Plaster, C Loebel, ...
Cancer Research 84 (6_Supplement), 4268-4268, 2024
2024
p53-R172H mutation confers gain-of-function properties and promotes metastasis in squamous cell carcinoma
G Efe, K Cunningham, RNF de Bobadilla, KJ Dunbar, K Sugiura, ...
Cancer Research 84 (6_Supplement), 1270-1270, 2024
2024
Sprouty4 is required for Mdm2 regulation of invasion, focal adhesion formation and metastasis in cells lacking p53
RM Queiroz, G Efe, A Guzman, N Hashimoto, Y Kawashima, T Tanaka, ...
bioRxiv, 2023.05. 08.539890, 2023
2023
Abstract LB160: Mdm2 regulates metastasis and associated cellular processes through modulation of Sprouty4 in a p53-independent manner
RM de Queiroz, G Efe, A Guzman, N Hashimoto, Y Kawashima, T Tanaka, ...
Cancer Research 83 (8_Supplement), LB160-LB160, 2023
2023
The role of mutant p53-mediated mechanisms in modulating the tumor microenvironment and promoting lung metastasis
G Efe, KM Cunningham, Q Tang, K Sugiura, K Dunbar, K Suzuki, ...
Cancer Research 83 (7_Supplement), 1289-1289, 2023
2023
Mutant p53-mediated CSF1/CSF1R signaling promotes tumor invasion and lung metastasis in esophageal squamous cell carcinoma
G Efe, Q Tang, KM Cunningham, K Sugiura, K Dunbar, K Regunath, ...
CANCER RESEARCH 83 (2), 2023
2023
Abstract B014: Mutant p53-mediated CSF1/CSF1R signaling promotes tumor invasion and lung metastasis in esophageal squamous cell carcinoma
G Efe, Q Tang, KM Cunningham, K Sugiura, K Dunbar, K Regunath, ...
Cancer Research 83 (2_Supplement_2), B014-B014, 2023
2023
Elucidation of CSF1 autocrine signaling mediated by mutant p53 in metastatic esophageal carcinoma
G Efe, Q Tang, R Cruz-Acuna, K Suzuki, K Sugiura, J Gabre, U Sachdeva, ...
Cancer Research 82 (12_Supplement), 2421-2421, 2022
2022
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