Acquired Resistance to KRASG12C Inhibition in Cancer MM Awad, S Liu, II Rybkin, KC Arbour, J Dilly, VW Zhu, ML Johnson, ... New England Journal of Medicine 384 (25), 2382-2393, 2021 | 575 | 2021 |
Cyclic uniaxial mechanical stretching of cells using a LEGO® parts-based mechanical stretcher system E Boulter, FS Tissot, J Dilly, S Pisano, CC Féral Journal of cell science 133 (1), jcs234666, 2020 | 22 | 2020 |
Oncogenic drivers and therapeutic vulnerabilities in KRAS wild-type pancreatic cancer H Singh, RB Keller, KS Kapner, J Dilly, S Raghavan, C Yuan, EF Cohen, ... Clinical Cancer Research 29 (22), 4627-4643, 2023 | 9 | 2023 |
Mechanisms of acquired resistance to KRAS G12C inhibition in cancer. M Awad, S Liu, K Arbour, V Zhu, M Johnson, R Heist, T Patil, G Riely, ... Cancer Research 81 (13), 2021 | 9 | 2021 |
Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer X Tong, AS Patel, E Kim, H Li, Y Chen, S Li, S Liu, J Dilly, KS Kapner, ... Cancer Cell, 2024 | 6 | 2024 |
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy M Holderfield, BJ Lee, J Jiang, A Tomlinson, KJ Seamon, A Mira, ... Nature, 1-8, 2024 | 4 | 2024 |
Tumor-selective activity of RAS-GTP inhibition in pancreatic cancer UN Wasko, J Jiang, TC Dalton, A Curiel-Garcia, AC Edwards, Y Wang, ... Nature, 1-3, 2024 | 2 | 2024 |
Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma UN Wasko, J Jiang, A Curiel-Garcia, Y Wang, B Lee, M Orlen, ... bioRxiv, 2023 | 2 | 2023 |
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy M Singh, M Holderfield, B Lee, J Jiang, A Tomlinson, K Seamon, A Mira, ... | 2 | 2023 |
RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling A Schaefer, RG Hodge, H Zhang, GA Hobbs, J Dilly, MV Huynh, ... Science signaling 16 (816), eadg5289, 2023 | 1 | 2023 |
GLIS3 drives a neural-like malignant state enriched after neoadjuvant treatment in pancreatic cancer JA Guo, J Su, C Shiau, A Jambhale, A Yang, W Wu, J Wang, ... Cancer Research 83 (7_Supplement), 5775-5775, 2023 | 1 | 2023 |
Dual RAF/MEK inhibitor VS-6766 enhances antitumor efficacy of KRAS G12C inhibitors through vertical inhibition of RAS, RAF and MEK S Coma, S Chowdhury, J Dilly, M Musteanu, M Barbacid, AJ Aguirre, ... Cancer Research 82 (12_Supplement), 402-402, 2022 | 1 | 2022 |
Dissecting acquired resistance to KRASG12D inhibition in a mouse model of pancreatic ductal adenocarcinoma J Dilly, L Abbassi, CJ Hennessey, GA Uribe, B Parent, A Yang, KS Kapner, ... Cancer Research 84 (6_Supplement), 1933-1933, 2024 | | 2024 |
Resistance to RAS-GTP inhibition in models of pancreatic ductal adenocarcinoma arises downstream of RAS effectors UN Wasko, J Jiang, TC Dalton, A Curiel-Garcia, AC Edwards, Y Wang, ... Cancer Research 84 (6_Supplement), 1927-1927, 2024 | | 2024 |
Abstract B101: Tumor-selective inhibition of active RAS in pancreatic ductal adenocarcinoma UN Wasko, J Jiang, L Tomassoni, Y Wang, B Lee, M Orlen, ... Cancer Research 84 (2_Supplement), B101-B101, 2024 | | 2024 |
Abstract A093: Deciphering acquired resistance to KRASG12D inhibition in a mouse model of pancreatic ductal adenocarcinoma J Dilly, L Abbassi, CJ Hennessey, GA Uribe, B Parent, A Yang, KS Kapner, ... Cancer Research 84 (2_Supplement), A093-A093, 2024 | | 2024 |
The RAF/MEK clamp avutometinib (VS-6766) enhances antitumor efficacy of KRAS G12C and G12D inhibitors through vertical inhibition of RAS, RAF and MEK S Coma, M Musteanu, C Caffarra, A Mira, E Patrucco, J Dilly, AJ Aguirre, ... MOLECULAR CANCER RESEARCH 21 (5), 2023 | | 2023 |
Abstract B025: The RAF/MEK clamp avutometinib (VS-6766) enhances antitumor efficacy of KRAS G12C and G12D inhibitors through vertical inhibition of RAS, RAF and MEK. S Coma, M Musteanu, C Caffarra, A Mira, E Patrucco, J Dilly, AJ Aguirre, ... Molecular Cancer Research 21 (5_Supplement), B025-B025, 2023 | | 2023 |
Systematic dissection of transcriptional states in pancreatic cancer JA Guo, J Su, A Jambhale, J Dilly, CJ Hennessey, C Shiau, P Yu, S Wang, ... CANCER RESEARCH 82 (22), 34-35, 2022 | | 2022 |
Abstract A001: Clinical-genomic analysis of KRAS wild-type pancreatic cancer confirms alternative targetable drivers and provides insight for age and risk related clinical … H Singh, RB Keller, KS Kapner, J Dilly, S Raghavan, C Yuan, E Cohen, ... Cancer Research 82 (22_Supplement), A001-A001, 2022 | | 2022 |