Bioanalytical LC–MS/MS of protein-based biopharmaceuticals I van den Broek, WMA Niessen, WD van Dongen Journal of Chromatography B 929, 161-179, 2013 | 236 | 2013 |
Quantitative bioanalysis of peptides by liquid chromatography coupled to (tandem) mass spectrometry I van den Broek, RW Sparidans, JHM Schellens, JH Beijnen Journal of Chromatography B 872 (1-2), 1-22, 2008 | 193 | 2008 |
Automated multiplex LC-MS/MS assay for quantifying serum apolipoproteins AI, B, CI, C-II, C-III, and E with qualitative apolipoprotein e phenotyping I van den Broek, FP Romijn, J Nouta, A van der Laarse, JW Drijfhout, ... Clinical chemistry 62 (1), 188-197, 2016 | 110 | 2016 |
Highly reproducible automated proteomics sample preparation workflow for quantitative mass spectrometry Q Fu, MP Kowalski, M Mastali, SJ Parker, K Sobhani, I Van Den Broek, ... Journal of proteome research 17 (1), 420-428, 2018 | 83 | 2018 |
Quantitative assay for six potential breast cancer biomarker peptides in human serum by liquid chromatography coupled to tandem mass spectrometry I Van den Broek, RW Sparidans, JHM Schellens, JH Beijnen Journal of Chromatography B 878 (5-6), 590-602, 2010 | 74 | 2010 |
LC–MS-based quantification of intact proteins: perspective for clinical and bioanalytical applications I van den Broek, WD van Dongen Bioanalysis 7 (15), 1943-1958, 2015 | 62 | 2015 |
Development and validation of a quantitative assay for the measurement of two HIV-fusion inhibitors, enfuvirtide and tifuvirtide, and one metabolite of enfuvirtide (M-20) in … I van den Broek, RW Sparidans, ADR Huitema, JHM Schellens, ... Journal of Chromatography B 837 (1-2), 49-58, 2006 | 59 | 2006 |
Quantifying protein measurands by peptide measurements: where do errors arise? I van den Broek, FP Romijn, NPM Smit, A van der Laarse, JW Drijfhout, ... Journal of proteome research 14 (2), 928-942, 2015 | 56 | 2015 |
Current trends in mass spectrometry of peptides and proteins: application to veterinary and sports‐doping control I van den Broek, M Blokland, MA Nessen, S Sterk Mass spectrometry reviews 34 (6), 571-594, 2015 | 52 | 2015 |
Serum degradome markers for the detection of breast cancer AWJ van Winden, I van den Broek, MCW Gast, JYMN Engwegen, ... Journal of proteome research 9 (8), 3781-3788, 2010 | 52 | 2010 |
Evaluation of interspecimen trypsin digestion efficiency prior to multiple reaction monitoring-based absolute protein quantification with native protein calibrators I van den Broek, NPM Smit, FP Romijn, A van der Laarse, AM Deelder, ... Journal of Proteome Research 12 (12), 5760-5774, 2013 | 50 | 2013 |
Quantification of serum apolipoproteins AI and B-100 in clinical samples using an automated SISCAPA–MALDI-TOF-MS workflow I van den Broek, J Nouta, M Razavi, R Yip, MR Bladergroen, FP Romijn, ... Methods 81, 74-85, 2015 | 48 | 2015 |
The absolute quantification of eight inter‐α‐trypsin inhibitor heavy chain 4 (ITIH4)‐derived peptides in serum from breast cancer patients I van den Broek, RW Sparidans, AWJ van Winden, MCW Gast, ... PROTEOMICS–Clinical Applications 4 (12), 931-939, 2010 | 46 | 2010 |
Application of volumetric absorptive microsampling for robust, high-throughput mass spectrometric quantification of circulating protein biomarkers I van den Broek, Q Fu, S Kushon, MP Kowalski, K Millis, A Percy, ... Clinical Mass Spectrometry 4, 25-33, 2017 | 45 | 2017 |
Enzymatic digestion as a tool for the LC–MS/MS quantification of large peptides in biological matrices: measurement of chymotryptic fragments from the HIV-1 fusion inhibitor … I van den Broek, RW Sparidans, JHM Schellens, JH Beijnen Journal of Chromatography B 854 (1-2), 245-259, 2007 | 43 | 2007 |
Metrological traceability in mass spectrometry-based targeted protein quantitation: a proof-of-principle study for serum apolipoproteins AI and B100 NPM Smit, FP Romijn, I van den Broek, JW Drijfhout, M Haex, ... Journal of Proteomics 109, 143-161, 2014 | 37 | 2014 |
Advances in quantifying apolipoproteins using LC-MS/MS technology: implications for the clinic I van den Broek, K Sobhani, JE Van Eyk Expert Review of Proteomics 14 (10), 869-880, 2017 | 26 | 2017 |
Sensitive liquid chromatography/tandem mass spectrometry assay for absolute quantification of ITIH4‐derived putative biomarker peptides in clinical serum samples I van den Broek, RW Sparidans, JHM Schellens, JH Beijnen Rapid Communications in Mass Spectrometry 24 (13), 1842-1850, 2010 | 26 | 2010 |
Liquid chromatography/tandem mass spectrometric method for the quantification of eight proteolytic fragments of ITIH4 with biomarker potential in human plasma and serum I van den Broek, RW Sparidans, JHM Schellens, JH Beijnen Rapid Communications in Mass Spectrometry 22 (18), 2915-2928, 2008 | 26 | 2008 |
Quality requirements for quantitative clinical chemistry proteomics N Smit, I van den Broek, FP Romijn, M Haex, AM Deelder, ... Transl Proteomics 2 (1), 1-13, 2014 | 17 | 2014 |