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Irene van den Broek
Irene van den Broek
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Year
Bioanalytical LC–MS/MS of protein-based biopharmaceuticals
I van den Broek, WMA Niessen, WD van Dongen
Journal of Chromatography B 929, 161-179, 2013
2362013
Quantitative bioanalysis of peptides by liquid chromatography coupled to (tandem) mass spectrometry
I van den Broek, RW Sparidans, JHM Schellens, JH Beijnen
Journal of Chromatography B 872 (1-2), 1-22, 2008
1932008
Automated multiplex LC-MS/MS assay for quantifying serum apolipoproteins AI, B, CI, C-II, C-III, and E with qualitative apolipoprotein e phenotyping
I van den Broek, FP Romijn, J Nouta, A van der Laarse, JW Drijfhout, ...
Clinical chemistry 62 (1), 188-197, 2016
1102016
Highly reproducible automated proteomics sample preparation workflow for quantitative mass spectrometry
Q Fu, MP Kowalski, M Mastali, SJ Parker, K Sobhani, I Van Den Broek, ...
Journal of proteome research 17 (1), 420-428, 2018
832018
Quantitative assay for six potential breast cancer biomarker peptides in human serum by liquid chromatography coupled to tandem mass spectrometry
I Van den Broek, RW Sparidans, JHM Schellens, JH Beijnen
Journal of Chromatography B 878 (5-6), 590-602, 2010
742010
LC–MS-based quantification of intact proteins: perspective for clinical and bioanalytical applications
I van den Broek, WD van Dongen
Bioanalysis 7 (15), 1943-1958, 2015
622015
Development and validation of a quantitative assay for the measurement of two HIV-fusion inhibitors, enfuvirtide and tifuvirtide, and one metabolite of enfuvirtide (M-20) in …
I van den Broek, RW Sparidans, ADR Huitema, JHM Schellens, ...
Journal of Chromatography B 837 (1-2), 49-58, 2006
592006
Quantifying protein measurands by peptide measurements: where do errors arise?
I van den Broek, FP Romijn, NPM Smit, A van der Laarse, JW Drijfhout, ...
Journal of proteome research 14 (2), 928-942, 2015
562015
Current trends in mass spectrometry of peptides and proteins: application to veterinary and sports‐doping control
I van den Broek, M Blokland, MA Nessen, S Sterk
Mass spectrometry reviews 34 (6), 571-594, 2015
522015
Serum degradome markers for the detection of breast cancer
AWJ van Winden, I van den Broek, MCW Gast, JYMN Engwegen, ...
Journal of proteome research 9 (8), 3781-3788, 2010
522010
Evaluation of interspecimen trypsin digestion efficiency prior to multiple reaction monitoring-based absolute protein quantification with native protein calibrators
I van den Broek, NPM Smit, FP Romijn, A van der Laarse, AM Deelder, ...
Journal of Proteome Research 12 (12), 5760-5774, 2013
502013
Quantification of serum apolipoproteins AI and B-100 in clinical samples using an automated SISCAPA–MALDI-TOF-MS workflow
I van den Broek, J Nouta, M Razavi, R Yip, MR Bladergroen, FP Romijn, ...
Methods 81, 74-85, 2015
482015
The absolute quantification of eight inter‐α‐trypsin inhibitor heavy chain 4 (ITIH4)‐derived peptides in serum from breast cancer patients
I van den Broek, RW Sparidans, AWJ van Winden, MCW Gast, ...
PROTEOMICS–Clinical Applications 4 (12), 931-939, 2010
462010
Application of volumetric absorptive microsampling for robust, high-throughput mass spectrometric quantification of circulating protein biomarkers
I van den Broek, Q Fu, S Kushon, MP Kowalski, K Millis, A Percy, ...
Clinical Mass Spectrometry 4, 25-33, 2017
452017
Enzymatic digestion as a tool for the LC–MS/MS quantification of large peptides in biological matrices: measurement of chymotryptic fragments from the HIV-1 fusion inhibitor …
I van den Broek, RW Sparidans, JHM Schellens, JH Beijnen
Journal of Chromatography B 854 (1-2), 245-259, 2007
432007
Metrological traceability in mass spectrometry-based targeted protein quantitation: a proof-of-principle study for serum apolipoproteins AI and B100
NPM Smit, FP Romijn, I van den Broek, JW Drijfhout, M Haex, ...
Journal of Proteomics 109, 143-161, 2014
372014
Advances in quantifying apolipoproteins using LC-MS/MS technology: implications for the clinic
I van den Broek, K Sobhani, JE Van Eyk
Expert Review of Proteomics 14 (10), 869-880, 2017
262017
Sensitive liquid chromatography/tandem mass spectrometry assay for absolute quantification of ITIH4‐derived putative biomarker peptides in clinical serum samples
I van den Broek, RW Sparidans, JHM Schellens, JH Beijnen
Rapid Communications in Mass Spectrometry 24 (13), 1842-1850, 2010
262010
Liquid chromatography/tandem mass spectrometric method for the quantification of eight proteolytic fragments of ITIH4 with biomarker potential in human plasma and serum
I van den Broek, RW Sparidans, JHM Schellens, JH Beijnen
Rapid Communications in Mass Spectrometry 22 (18), 2915-2928, 2008
262008
Quality requirements for quantitative clinical chemistry proteomics
N Smit, I van den Broek, FP Romijn, M Haex, AM Deelder, ...
Transl Proteomics 2 (1), 1-13, 2014
172014
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