The emergence of cyclic peptides: The potential of bioengineered peptide drugs P Thapa, MJ Espiritu, C Cabalteja, JP Bingham International Journal of Peptide Research and Therapeutics 20, 545-551, 2014 | 49 | 2014 |
From nature to creation: Going around in circles, the art of peptide cyclization RY Zhang, P Thapa, MJ Espiritu, V Menon, JP Bingham Bioorganic & Medicinal Chemistry 26 (6), 1135-1150, 2018 | 46 | 2018 |
A 21st-century approach to age-old problems: the ascension of biologics in clinical therapeutics MJ Espiritu, AC Collier, JP Bingham Drug discovery today 19 (8), 1109-1113, 2014 | 37 | 2014 |
Incorporation of post-translational modified amino acids as an approach to increase both chemical and biological diversity of conotoxins and conopeptides MJ Espiritu, CC Cabalteja, CK Sugai, JP Bingham Amino acids 46, 125-151, 2014 | 25 | 2014 |
Conotoxins and their regulatory considerations P Thapa, MJ Espiritu, CC Cabalteja, JP Bingham Regulatory toxicology and pharmacology 70 (1), 197-202, 2014 | 14 | 2014 |
Mechanisms of herb-drug interactions involving cinnamon and CYP2A6: focus on time-dependent inhibition by cinnamaldehyde and 2-methoxycinnamaldehyde MJ Espiritu, J Chen, J Yadav, M Larkin, RD Pelletier, JM Chan, S Natesan, ... Drug Metabolism and Disposition 48 (10), 1028-1043, 2020 | 8 | 2020 |
Development and validation of a sensitive and specific LC–MS/MS cocktail assay for CYP450 enzymes: Application to study the effect of catechin on rat hepatic CYP activity V Nguyen, M Espiritu, F Elbarbry Biomedical Chromatography 34 (3), e4789, 2020 | 8 | 2020 |
Disulfide bond and topological isomerization of the conopeptide PNID: disulfide bonds with a twist MJ Espiritu University of Hawai'i at Manoa, 2017 | 4 | 2017 |
t‐boc synthesis of huwentoxin‐i through native chemical ligation incorporating a trifluoromethanesulfonic acid cleavage strategy P Thapa, CC Cabalteja, EE Philips III, MJ Espiritu, S Peigneur, BG Mille, ... Peptide Science 106 (5), 737-745, 2016 | 4 | 2016 |
Research into the Bioengineering of a Novel α-Conotoxin from the Milked Venom of Conus obscurus S Wiere, C Sugai, MJ Espiritu, VP Aurelio, CD Reyes, N Yuzon, ... International Journal of Molecular Sciences 23 (20), 12096, 2022 | 3 | 2022 |
Characterization of the Native Disulfide Isomers of the Novel χ-Conotoxin PnID: Implications for Further Increasing Conotoxin Diversity MJ Espiritu, JK Taylor, CK Sugai, P Thapa, NM Loening, E Gusman, ... Marine Drugs 21 (2), 61, 2023 | 1 | 2023 |
Mechanisms of herb-drug interactions involving cinnamon and cytochrome P450 2A6: focus on time-dependent inhibition by cinnamaldehyde and 2-methoxycinnamaldehyde MJ Espiritu, J Chen, J Yadav, M Larkin, RD Pelletier, JM Chan, S Natesan, ... Drug Metabolism and Disposition, 2020 | 1 | 2020 |
Inhibition of Soluble Epoxide Hydrolase by Natural Isothiocyanates F Elbarbry, MJ Espiritu, K Soo, B Yee, J Taylor Biochemical and Biophysical Research Communications, 150261, 2024 | | 2024 |
Inhibition of Major Cytochrome P450 Enzyme Activities in Human Liver Microsomes by 9‐a and WES‐1, two Novel Carbonic Anhydrase Inhibitors. V Nguyn, M Espiritu, W Eldehna, M Abdelrahman, H Abdel-Aziz, ... The FASEB Journal 34 (S1), 1-1, 2020 | | 2020 |
Investigation into the Metabolic Limitations of Alpha Conotoxins as Drugs in the Gastrointestinal Tract E Gusman, A Sandbach, M Espiritu The FASEB Journal 34 (S1), 1-1, 2020 | | 2020 |
P153-The natural product 2-methoxy trans-cinnamaldehyde is a time dependent inhibitor of the nicotine and letrozole metabolizing enzyme cytochrome P450 2A6 M Espiritu, M Larkin, H True, J Chan, B Stamper, J Harrelson Drug Metabolism and Pharmacokinetics 35 (1), S69-S69, 2020 | | 2020 |
Mechanisms for the Time‐dependent Inhibition of the Human Nicotine‐metabolizing Enzyme CYP2A6 by Cinnamaldehyde: Evidence for Formyl Hydrogen Abstraction and Heme Degradation M Espiritu, M Larkin, B Cao, R Pelletier, A Nguyen, J Chan, J Harrelson The FASEB Journal 33 (S1), 673.4-673.4, 2019 | | 2019 |
Modulation of Arachidonic Acid Metabolism in the Rat Kidney by Quercetin: Implications for Regulation of Blood Pressure F Elbarbry, J Harrelson, M Espiritu, T Pham, K Ibrahim The FASEB Journal 32, 561.10-561.10, 2018 | | 2018 |
A Mechanistic Study on the Inhibition of Nicotine Metabolism by Trans‐Cinnamaldehyde M Espiritu, S Black, C Johnston, J Chan, J Harrelson The FASEB Journal 32, 833.11-833.11, 2018 | | 2018 |
Pharmaceutical Regulatory Affairs: Open Access P Thapa, MJ Espiritu, CC Cabalteja, JP Bingham | | 2014 |