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Michael Espiritu
Michael Espiritu
Pacific University School of Pharmacy
Verified email at pacificu.edu
Title
Cited by
Cited by
Year
The emergence of cyclic peptides: The potential of bioengineered peptide drugs
P Thapa, MJ Espiritu, C Cabalteja, JP Bingham
International Journal of Peptide Research and Therapeutics 20, 545-551, 2014
492014
From nature to creation: Going around in circles, the art of peptide cyclization
RY Zhang, P Thapa, MJ Espiritu, V Menon, JP Bingham
Bioorganic & Medicinal Chemistry 26 (6), 1135-1150, 2018
462018
A 21st-century approach to age-old problems: the ascension of biologics in clinical therapeutics
MJ Espiritu, AC Collier, JP Bingham
Drug discovery today 19 (8), 1109-1113, 2014
372014
Incorporation of post-translational modified amino acids as an approach to increase both chemical and biological diversity of conotoxins and conopeptides
MJ Espiritu, CC Cabalteja, CK Sugai, JP Bingham
Amino acids 46, 125-151, 2014
252014
Conotoxins and their regulatory considerations
P Thapa, MJ Espiritu, CC Cabalteja, JP Bingham
Regulatory toxicology and pharmacology 70 (1), 197-202, 2014
142014
Mechanisms of herb-drug interactions involving cinnamon and CYP2A6: focus on time-dependent inhibition by cinnamaldehyde and 2-methoxycinnamaldehyde
MJ Espiritu, J Chen, J Yadav, M Larkin, RD Pelletier, JM Chan, S Natesan, ...
Drug Metabolism and Disposition 48 (10), 1028-1043, 2020
82020
Development and validation of a sensitive and specific LC–MS/MS cocktail assay for CYP450 enzymes: Application to study the effect of catechin on rat hepatic CYP activity
V Nguyen, M Espiritu, F Elbarbry
Biomedical Chromatography 34 (3), e4789, 2020
82020
Disulfide bond and topological isomerization of the conopeptide PNID: disulfide bonds with a twist
MJ Espiritu
University of Hawai'i at Manoa, 2017
42017
t‐boc synthesis of huwentoxin‐i through native chemical ligation incorporating a trifluoromethanesulfonic acid cleavage strategy
P Thapa, CC Cabalteja, EE Philips III, MJ Espiritu, S Peigneur, BG Mille, ...
Peptide Science 106 (5), 737-745, 2016
42016
Research into the Bioengineering of a Novel α-Conotoxin from the Milked Venom of Conus obscurus
S Wiere, C Sugai, MJ Espiritu, VP Aurelio, CD Reyes, N Yuzon, ...
International Journal of Molecular Sciences 23 (20), 12096, 2022
32022
Characterization of the Native Disulfide Isomers of the Novel χ-Conotoxin PnID: Implications for Further Increasing Conotoxin Diversity
MJ Espiritu, JK Taylor, CK Sugai, P Thapa, NM Loening, E Gusman, ...
Marine Drugs 21 (2), 61, 2023
12023
Mechanisms of herb-drug interactions involving cinnamon and cytochrome P450 2A6: focus on time-dependent inhibition by cinnamaldehyde and 2-methoxycinnamaldehyde
MJ Espiritu, J Chen, J Yadav, M Larkin, RD Pelletier, JM Chan, S Natesan, ...
Drug Metabolism and Disposition, 2020
12020
Inhibition of Soluble Epoxide Hydrolase by Natural Isothiocyanates
F Elbarbry, MJ Espiritu, K Soo, B Yee, J Taylor
Biochemical and Biophysical Research Communications, 150261, 2024
2024
Inhibition of Major Cytochrome P450 Enzyme Activities in Human Liver Microsomes by 9‐a and WES‐1, two Novel Carbonic Anhydrase Inhibitors.
V Nguyn, M Espiritu, W Eldehna, M Abdelrahman, H Abdel-Aziz, ...
The FASEB Journal 34 (S1), 1-1, 2020
2020
Investigation into the Metabolic Limitations of Alpha Conotoxins as Drugs in the Gastrointestinal Tract
E Gusman, A Sandbach, M Espiritu
The FASEB Journal 34 (S1), 1-1, 2020
2020
P153-The natural product 2-methoxy trans-cinnamaldehyde is a time dependent inhibitor of the nicotine and letrozole metabolizing enzyme cytochrome P450 2A6
M Espiritu, M Larkin, H True, J Chan, B Stamper, J Harrelson
Drug Metabolism and Pharmacokinetics 35 (1), S69-S69, 2020
2020
Mechanisms for the Time‐dependent Inhibition of the Human Nicotine‐metabolizing Enzyme CYP2A6 by Cinnamaldehyde: Evidence for Formyl Hydrogen Abstraction and Heme Degradation
M Espiritu, M Larkin, B Cao, R Pelletier, A Nguyen, J Chan, J Harrelson
The FASEB Journal 33 (S1), 673.4-673.4, 2019
2019
Modulation of Arachidonic Acid Metabolism in the Rat Kidney by Quercetin: Implications for Regulation of Blood Pressure
F Elbarbry, J Harrelson, M Espiritu, T Pham, K Ibrahim
The FASEB Journal 32, 561.10-561.10, 2018
2018
A Mechanistic Study on the Inhibition of Nicotine Metabolism by Trans‐Cinnamaldehyde
M Espiritu, S Black, C Johnston, J Chan, J Harrelson
The FASEB Journal 32, 833.11-833.11, 2018
2018
Pharmaceutical Regulatory Affairs: Open Access
P Thapa, MJ Espiritu, CC Cabalteja, JP Bingham
2014
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Articles 1–20