| PEGylated IL-10 (Pegilodecakin) induces systemic immune activation, CD8+ T cell invigoration and polyclonal T cell expansion in cancer patients A Naing, JR Infante, KP Papadopoulos, IH Chan, C Shen, NP Ratti, ... Cancer Cell 34 (5), 775-791. e3, 2018 | 216 | 2018 |
| Illuminating the Onco-GPCRome: Novel G protein–coupled receptor-driven oncocrine networks and targets for cancer immunotherapy V Wu, H Yeerna, N Nohata, J Chiou, O Harismendy, F Raimondi, A Inoue, ... Journal of biological chemistry 294 (29), 11062-11086, 2019 | 152 | 2019 |
| Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4 Z Wang, VH Wu, MM Allevato, M Gilardi, Y He, J Luis Callejas-Valera, ... Nature communications 10 (1), 5546, 2019 | 121 | 2019 |
| 4E-BP1 is a tumor suppressor protein reactivated by mTOR inhibition in head and neck cancer Z Wang, X Feng, AA Molinolo, D Martin, L Vitale-Cross, N Nohata, M Ando, ... Cancer research 79 (7), 1438-1450, 2019 | 63 | 2019 |
| Pseudomonas putida F1 has multiple chemoreceptors with overlapping specificity for organic acids RE Parales, RA Luu, GY Chen, X Liu, V Wu, P Lin, JG Hughes, ... Microbiology 159 (Pt_6), 1086-1096, 2013 | 60 | 2013 |
| The potentiation of IFN-γ and induction of cytotoxic proteins by pegylated IL-10 in human CD8 T cells IH Chan, V Wu, M Bilardello, E Mar, M Oft, P Van Vlasselaer, JB Mumm Journal of Interferon & Cytokine Research 35 (12), 948-955, 2015 | 59 | 2015 |
| Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC R Saddawi-Konefka, A O’Farrell, F Faraji, L Clubb, MM Allevato, ... Nature communications 13 (1), 4298, 2022 | 51 | 2022 |
| Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer Z Wang, Y Goto, MM Allevato, VH Wu, R Saddawi-Konefka, M Gilardi, ... Nature communications 12 (1), 2383, 2021 | 39 | 2021 |
| Metformin inhibits progression of head and neck squamous cell carcinoma by acting directly on carcinoma-initiating cells X Wu, H Yeerna, Y Goto, T Ando, VH Wu, X Zhang, Z Wang, ... Cancer research 79 (17), 4360-4370, 2019 | 36 | 2019 |
| A threshold model for T-cell activation in the era of checkpoint blockade immunotherapy K Guram, SS Kim, V Wu, PD Sanders, S Patel, SP Schoenberger, ... Frontiers in immunology 10, 491, 2019 | 35 | 2019 |
| Microneedle-mediated intratumoral delivery of anti-CTLA-4 promotes cDC1-dependent eradication of oral squamous cell carcinoma with limited irAEs M Gilardi, R Saddawi-Konefka, VH Wu, MA Lopez-Ramirez, Z Wang, ... Molecular cancer therapeutics 21 (4), 616-624, 2022 | 23 | 2022 |
| Plasmacytoid dendritic cell-derived IFNα modulates Th17 differentiation during early Bordetella pertussis infection in mice V Wu, AA Smith, H You, TA Nguyen, R Ferguson, M Taylor, JE Park, ... Mucosal immunology 9 (3), 777-786, 2016 | 20 | 2016 |
| PEG-rIL-10 treatment decreases FoxP3+ Tregs despite upregulation of intratumoral IDO IH Chan, V Wu, M Bilardello, B Jorgenson, H Bal, S McCauley, ... Oncoimmunology 5 (7), e1197458, 2016 | 17 | 2016 |
| IL-10: expanding the immune oncology horizon IH Chan, V Wu, S McCauley, EA Grimm, JB Mumm Receptors & clinical investigation 2 (4), 2015 | 14 | 2015 |
| The GPCR–Gαs–PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure VH Wu, BS Yung, F Faraji, R Saddawi-Konefka, Z Wang, AT Wenzel, ... Nature immunology 24 (8), 1318-1330, 2023 | 11 | 2023 |
| Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response M Pagadala, TJ Sears, VH Wu, E Pérez-Guijarro, H Kim, A Castro, ... Nature communications 14 (1), 2744, 2023 | 9 | 2023 |
| Differential Expression of Alpha 4 Integrins on Effector Memory T Helper Cells during Bordetella Infections. Delayed Responses in Bordetella pertussis TM Nguyen, D Ravindra, B Kwong, S Waheed, R Ferguson, N Tarlton, ... PLoS One 7 (12), e52903, 2012 | 7 | 2012 |
| Germline variants that influence the tumor immune microenvironment also drive response to immunotherapy M Pagadala, VH Wu, E Pérez-Guijarro, H Kim, A Castro, J Talwar, ... BioRxiv, 2021 | 2 | 2021 |
| Complete genome sequence and methylome analysis of Thermoactinomyces vulgaris 2H H Mankai, BP Anton, V Wu, T Vincze, RJ Roberts, F Limam, A Fomenkov Microbiology Resource Announcements 8 (32), 10.1128/mra. 00657-19, 2019 | 2 | 2019 |
| GPCRs in head and neck squamous cell carcinoma VH Wu, JS Gutkind Improving the therapeutic ratio in head and neck cancer, 317-334, 2020 | 1 | 2020 |
J. Silvio Gutkind, Ph.D.UCSD, Distinguished Professor and Chair, Dept. Pharmacology, AD Basic Science Moores Cancer CenterVerified email at ucsd.edu
