Identification of selective inhibitors of cancer stem cells by high-throughput screening PB Gupta, TT Onder, G Jiang, K Tao, C Kuperwasser, RA Weinberg, ... Cell 138 (4), 645-659, 2009 | 2849 | 2009 |
Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells PB Gupta, CM Fillmore, G Jiang, SD Shapira, K Tao, C Kuperwasser, ... Cell 146 (4), 633-644, 2011 | 1648 | 2011 |
Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state CL Chaffer, I Brueckmann, C Scheel, AJ Kaestli, PA Wiggins, ... Proceedings of the National Academy of Sciences 108 (19), 7950-7955, 2011 | 1329 | 2011 |
Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy CM Fillmore, C Kuperwasser Breast cancer research 10, 1-13, 2008 | 1320 | 2008 |
Reconstruction of functionally normal and malignant human breast tissues in mice C Kuperwasser, T Chavarria, M Wu, G Magrane, JW Gray, L Carey, ... Proceedings of the National Academy of Sciences 101 (14), 4966-4971, 2004 | 980 | 2004 |
The melanocyte differentiation program predisposes to metastasis after neoplastic transformation PB Gupta, C Kuperwasser, JP Brunet, S Ramaswamy, WL Kuo, JW Gray, ... Nature genetics 37 (10), 1047-1054, 2005 | 513 | 2005 |
Phenotypic plasticity: driver of cancer initiation, progression, and therapy resistance PB Gupta, I Pastushenko, A Skibinski, C Blanpain, C Kuperwasser Cell stem cell 24 (1), 65-78, 2019 | 503 | 2019 |
A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer TA DiMeo, K Anderson, P Phadke, C Feng, CM Perou, S Naber, ... Cancer research 69 (13), 5364-5373, 2009 | 494 | 2009 |
Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate TA Proia, PJ Keller, PB Gupta, I Klebba, AD Jones, M Sedic, H Gilmore, ... Cell stem cell 8 (2), 149-163, 2011 | 423 | 2011 |
Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling CM Fillmore, PB Gupta, JA Rudnick, S Caballero, PJ Keller, ES Lander, ... Proceedings of the National Academy of Sciences 107 (50), 21737-21742, 2010 | 333 | 2010 |
Defining the cellular precursors to human breast cancer PJ Keller, LM Arendt, A Skibinski, T Logvinenko, I Klebba, S Dong, ... Proceedings of the National Academy of Sciences 109 (8), 2772-2777, 2012 | 277 | 2012 |
Obesity promotes breast cancer by CCL2-mediated macrophage recruitment and angiogenesis LM Arendt, J McCready, PJ Keller, DD Baker, SP Naber, V Seewaldt, ... Cancer research 73 (19), 6080-6093, 2013 | 267 | 2013 |
A mouse model of human breast cancer metastasis to human bone C Kuperwasser, S Dessain, BE Bierbaum, D Garnet, K Sperandio, ... Cancer research 65 (14), 6130-6138, 2005 | 258 | 2005 |
Mapping the cellular and molecular heterogeneity of normal and malignant breast tissues and cultured cell lines PJ Keller, AF Lin, LM Arendt, I Klebba, AD Jones, JA Rudnick, TA DiMeo, ... Breast cancer research 12, 1-17, 2010 | 241 | 2010 |
Development of spontaneous mammary tumors in BALB/c p53 heterozygous mice: a model for Li-Fraumeni syndrome C Kuperwasser, GD Hurlbut, FS Kittrell, ES Dickinson, R Laucirica, ... The American journal of pathology 157 (6), 2151-2159, 2000 | 239 | 2000 |
A mammary-specific model demonstrates the role of the p53 tumor suppressor gene in tumor development DJ Jerry, FS Kittrell, C Kuperwasser, R Laucirica, ES Dickinson, ... Oncogene 19 (8), 1052-1058, 2000 | 230 | 2000 |
Human breast cancer stem cell markers CD44 and CD24: enriching for cells with functional properties in mice or in man? C Fillmore, C Kuperwasser Breast cancer research 9, 1-3, 2007 | 207 | 2007 |
Systemic stromal effects of estrogen promote the growth of estrogen receptor–negative cancers PB Gupta, D Proia, O Cingoz, J Weremowicz, SP Naber, RA Weinberg, ... Cancer research 67 (5), 2062-2071, 2007 | 193 | 2007 |
The origin of breast tumor heterogeneity A Skibinski, C Kuperwasser Oncogene 34 (42), 5309-5316, 2015 | 191 | 2015 |
GLI1 regulates a novel neuropilin‐2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation HL Goel, B Pursell, C Chang, LM Shaw, J Mao, K Simin, P Kumar, ... EMBO molecular medicine 5 (4), 488-508, 2013 | 191 | 2013 |