Unprecedented cyclization catalyzed by a cytochrome P450 in benzastatin biosynthesis H Tsutsumi, Y Katsuyama, M Izumikawa, M Takagi, M Fujie, N Satoh, ... Journal of the American Chemical Society 140 (21), 6631-6639, 2018 | 85 | 2018 |
Structural and Molecular Basis of the Catalytic Mechanism of Geranyl Pyrophosphate C6‐Methyltransferase: Creation of an Unprecedented Farnesyl Pyrophosphate C6‐Methyltransferase H Tsutsumi, Y Moriwaki, T Terada, K Shimizu, K Shin‐ya, Y Katsuyama, ... Angewandte Chemie International Edition 61 (1), e202111217, 2022 | 11 | 2022 |
Comprehensive analysis of biosynthetic gene clusters in bacteria and discovery of Tumebacillus as a potential producer of natural products Y Kikuchi, M Kawashima, M Iwatsuki, A Kimishima, H Tsutsumi, Y Asami, ... The Journal of Antibiotics 76 (6), 316-323, 2023 | 6 | 2023 |
Rediscovery of Tetronomycin as a Broad-Spectrum and Potent Antibiotic against Drug-Resistant Gram-Positive Bacteria A Kimishima, I Tsuruoka, H Kanto, H Tsutsumi, N Arima, K Sakai, ... ACS omega 8 (12), 11556-11563, 2023 | 3 | 2023 |
Insights into the structure–activity relationship of a type III secretion system inhibitor, aurodox A Kimishima, D Hagimoto, M Honsho, Y Watanabe, M Iwatsuki, ... Bioorganic & Medicinal Chemistry Letters 69, 128779, 2022 | 3 | 2022 |
Identification and Analysis of the Biosynthetic Gene Cluster for the Indolizidine Alkaloid Iminimycin in Streptomyces griseus H Tsutsumi, Y Katsuyama, T Tezuka, R Miyano, Y Inahashi, Y Takahashi, ... ChemBioChem 23 (3), e202100517, 2022 | 2 | 2022 |
Design and Synthesis of d-Ala-d-Ala Silica Gel for a Binding Mode-Based Physicochemical Screening Method A Kimishima, Y Suzuki, S Kosaka, M Honsho, S Honma, K Sakai, ... ACS omega 8 (42), 39035-39040, 2023 | 1 | 2023 |
Emblestatin: a new peptide antibiotic from Embleya scabrispora K20-0267 Y Awano, H Tsutsumi, Y Kikuchi, A Kimishima, M Iwatsuki, Y Asami, ... The Journal of Antibiotics 76 (10), 592-597, 2023 | 1 | 2023 |
Isolation, Total Synthesis and the Structure Determination of the Antifungal Macrocyclic Depsipeptide, Tetraselide H Nakahara, G Sennari, H Azami, H Tsutsumi, Y Noguchi, Y Watanabe, ... | | 2024 |
A new polyene macrolide antibiotic, machidamycin, produced by Streptomyces sp. K22-0017 Y Awano, R Ishii, Y Takahashi, H Tsutsumi, Y Watanabe, M Sonoda, ... The Journal of Antibiotics, 1-4, 2024 | | 2024 |
Binding Mode-Based Physicochemical Screening Method Using d-Ala-d-Ala Silica Gel and Chemical Modification Approach to Facilitate Discovery of New Macrolactams … A Kimishima, Y Suzuki, S Kosaka, M Honsho, S Honma, H Tsutsumi, ... ACS omega 9 (15), 17415-17422, 2024 | | 2024 |
Akedanones A–C, In Vitro and In Vivo Antiplasmodial 2,3-Dihydronaphthoquinones Produced by Streptomyces sp. K20-0187 S Kimura, Y Watanabe, Y Kikuchi, S Shibasaki, H Tsutsumi, Y Inahashi, ... Journal of Natural Products, 2024 | | 2024 |
A new tetronomycin analog, broad‐spectrum and potent antibiotic against drug‐resistant Gram‐positive bacteria A Kimishima, I Tsuruoka, H Tsutsumi, M Honsho, S Honma, H Matsui, ... Chemistry & Biodiversity 21 (2), e202301834, 2024 | | 2024 |
Re-evaluation and a Structure–Activity Relationship Study for the Selective Anti-anaerobic Bacterial Activity of Luminamicin toward Target Identification A Kimishima, S Negami, I Tsuruoka, H Tsutsumi, H Matsui, M Sugamata, ... ACS Infectious Diseases 9 (8), 1602-1609, 2023 | | 2023 |
ISOLATION OF NATURAL PRODUCTS FROM THE GENUS TUMEBACILLUS, NEW MICROBIAL SOURCE SELECTED BY GENOME ANALYSIS Y Kikuchi, M Kawashima, M Iwatsuki, A Kimishima, H Tsutsumi, Y Asami, ... 4th International Conference on Natural Product Discovery and Development in …, 2023 | | 2023 |
SELECTIVE ISOLATION OF RARE ACTINOMYCETES USING AGAR MEDIUM CONTAINING LYSOZYME AND SEARCH FOR NOVEL BIOACTIVE COMPOUNDS. Y Awano, H Kanto, A Take, Y Kikuchi, A Kimishima, H Tsutsumi, ... 4th International Conference on Natural Product Discovery and Development in …, 2023 | | 2023 |
Enzymatic synthesis of non-natural flavonoids by combining geranyl pyrophosphate C6-methyltransferase and aromatic prenyltransferase H Tsutsumi, N Urano, Y Katsuyama, Y Ohnishi Bioscience, Biotechnology, and Biochemistry 86 (9), 1270-1275, 2022 | | 2022 |
Formation of 5-or 6-Membered Ring via Nitrene Formation and Addition by a Cytochrome P450 in Benzastatin Biosynthesis H Tsutsumi, Y Katsuyama, Y ONISHI 有機合成化学協会誌 77 (9), 912-919, 2019 | | 2019 |