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William E. O'Gorman
William E. O'Gorman
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Year
Peripheral T cell expansion predicts tumour infiltration and clinical response
TD Wu, S Madireddi, PE de Almeida, R Banchereau, YJJ Chen, AS Chitre, ...
Nature 579 (7798), 274-278, 2020
5102020
Rational strain selection and engineering creates a broad-spectrum, systemically effective oncolytic poxvirus, JX-963
SH Thorne, THH Hwang, WE O’Gorman, DL Bartlett, S Sei, F Kanji, ...
The Journal of clinical investigation 117 (11), 3350-3358, 2007
2652007
Cutting edge: Mechanisms of IL-2–dependent maintenance of functional regulatory T cells
L Barron, H Dooms, KK Hoyer, W Kuswanto, J Hofmann, WE O’Gorman, ...
The Journal of Immunology 185 (11), 6426-6430, 2010
2602010
Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling
T Sathaliyawala, WE O'Gorman, M Greter, M Bogunovic, V Konjufca, ...
Immunity 33 (4), 597-606, 2010
1982010
The initial phase of an immune response functions to activate regulatory T cells
WE O'Gorman, H Dooms, SH Thorne, WF Kuswanto, EF Simonds, ...
The Journal of Immunology 183 (1), 332-339, 2009
1872009
Intratumoral plasma cells predict outcomes to PD-L1 blockade in non-small cell lung cancer
NS Patil, BY Nabet, S Müller, H Koeppen, W Zou, J Giltnane, A Au-Yeung, ...
Cancer cell 40 (3), 289-300. e4, 2022
1732022
Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses
KL Banta, X Xu, AS Chitre, A Au-Yeung, C Takahashi, WE O’Gorman, ...
Immunity 55 (3), 512-526. e9, 2022
1562022
Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes
MK Rahim, TLH Okholm, KB Jones, EE McCarthy, CC Liu, JL Yee, ...
Cell 186 (6), 1127-1143. e18, 2023
932023
Duration of antigen receptor signaling determines T-cell tolerance or activation
SD Katzman, WE O'Gorman, AV Villarino, E Gallo, RS Friedman, ...
Proceedings of the National Academy of Sciences 107 (42), 18085-18090, 2010
882010
Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade
R Banchereau, AS Chitre, A Scherl, TD Wu, NS Patil, P de Almeida, ...
Journal for ImmunoTherapy of Cancer 9 (4), 2021
852021
Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity
M Uzzan, JC Martin, L Mesin, AE Livanos, T Castro-Dopico, R Huang, ...
Nature medicine 28 (4), 766-779, 2022
832022
The potential functions of primary microRNAs in target recognition and repression
RD Trujillo, SB Yue, Y Tang, WE O'gorman, CZ Chen
The EMBO journal 29 (19), 3272-3285, 2010
802010
Single-cell systems-level analysis of human Toll-like receptor activation defines a chemokine signature in patients with systemic lupus erythematosus
WE O'Gorman, EWY Hsieh, ES Savig, PF Gherardini, JD Hernandez, ...
Journal of Allergy and Clinical Immunology 136 (5), 1326-1336, 2015
792015
Mass cytometry panel optimization through the designed distribution of signal interference
C Takahashi, A Au‐Yeung, F Fuh, T Ramirez‐Montagut, C Bolen, ...
Cytometry Part A 91 (1), 39-47, 2017
752017
Late-differentiated effector neoantigen-specific CD8+ T cells are enriched in peripheral blood of non-small cell lung carcinoma patients responding to atezolizumab treatment
M Fehlings, S Jhunjhunwala, M Kowanetz, WE O’Gorman, PS Hegde, ...
Journal for immunotherapy of cancer 7, 1-15, 2019
702019
Mass cytometry identifies a distinct monocyte cytokine signature shared by clinically heterogeneous pediatric SLE patients
WE O'Gorman, DS Kong, IM Balboni, P Rudra, CR Bolen, D Ghosh, ...
Journal of autoimmunity 81, 74-89, 2017
602017
Quantitative comparison of conventional and t-SNE-guided gating analyses
S Toghi Eshghi, A Au-Yeung, C Takahashi, CR Bolen, MN Nyachienga, ...
Frontiers in immunology 10, 1194, 2019
572019
The split virus influenza vaccine rapidly activates immune cells through Fcγ receptors
WE O’Gorman, H Huang, YL Wei, KL Davis, MD Leipold, SC Bendall, ...
Vaccine 32 (45), 5989-5997, 2014
412014
Alternate mechanisms of initial pattern recognition drive differential immune responses to related poxviruses
WE O'Gorman, P Sampath, EF Simonds, R Sikorski, M O'Malley, ...
Cell host & microbe 8 (2), 174-185, 2010
402010
Distinct regulation of integrin-dependent T cell conjugate formation and NF-κB activation by the adapter protein ADAP
BJ Burbach, R Srivastava, RB Medeiros, WE O'Gorman, EJ Peterson, ...
The Journal of Immunology 181 (7), 4840-4851, 2008
392008
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