| Sepsis pathophysiology, chronic critical illness, and persistent inflammation-immunosuppression and catabolism syndrome JC Mira, LF Gentile, BJ Mathias, PA Efron, SC Brakenridge, AM Mohr, ... Critical care medicine 45 (2), 253-262, 2017 | 460 | 2017 |
| Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections KE Remy, M Mazer, DA Striker, AH Ellebedy, AH Walton, J Unsinger, ... JCI insight 5 (17), 2020 | 317 | 2020 |
| Artificial intelligence and surgical decision-making TJ Loftus, PJ Tighe, AC Filiberto, PA Efron, SC Brakenridge, AM Mohr, ... JAMA surgery 155 (2), 148-158, 2020 | 295 | 2020 |
| Effect of antithrombotic therapy on clinical outcomes in outpatients with clinically stable symptomatic COVID-19: the ACTIV-4B randomized clinical trial JM Connors, MM Brooks, FC Sciurba, JA Krishnan, JR Bledsoe, ... Jama 326 (17), 1703-1712, 2021 | 254 | 2021 |
| Human myeloid-derived suppressor cells are associated with chronic immune suppression after severe sepsis/septic shock B Mathias, AL Delmas, T Ozrazgat-Baslanti, EL Vanzant, BE Szpila, ... Annals of surgery 265 (4), 827-834, 2017 | 240 | 2017 |
| Evaluation and management of blunt traumatic aortic injury: a practice management guideline from the Eastern Association for the Surgery of Trauma N Fox, D Schwartz, JH Salazar, ER Haut, P Dahm, JH Black, ... Journal of Trauma and Acute Care Surgery 78 (1), 136-146, 2015 | 228 | 2015 |
| Chronic critical illness and the persistent inflammation, immunosuppression, and catabolism syndrome RB Hawkins, SL Raymond, JA Stortz, H Horiguchi, SC Brakenridge, ... Frontiers in immunology 9, 1511, 2018 | 226 | 2018 |
| Persistent inflammation, immunosuppression and catabolism syndrome JC Mira, SC Brakenridge, LL Moldawer, FA Moore Critical care clinics 33 (2), 245-258, 2017 | 201 | 2017 |
| Immune checkpoint inhibition in sepsis: a phase 1b randomized, placebo-controlled, single ascending dose study of antiprogrammed cell death-ligand 1 antibody (BMS-936559) RS Hotchkiss, E Colston, S Yende, DC Angus, LL Moldawer, ED Crouser, ... Critical care medicine 47 (5), 632-642, 2019 | 182 | 2019 |
| Immunotherapies for COVID-19: lessons learned from sepsis KE Remy, SC Brakenridge, B Francois, T Daix, CS Deutschman, ... The Lancet Respiratory Medicine 8 (10), 946-949, 2020 | 169 | 2020 |
| Innate immunity in the persistent inflammation, immunosuppression, and catabolism syndrome and its implications for therapy H Horiguchi, TJ Loftus, RB Hawkins, SL Raymond, JA Stortz, MKK Hollen, ... Frontiers in immunology 9, 595, 2018 | 150 | 2018 |
| Prospective evaluation of the sensitivity of physical examination in chest trauma F Bokhari, S Brakenridge, K Nagy, R Roberts, R Smith, K Joseph, G An, ... Journal of Trauma and Acute Care Surgery 53 (6), 1135-1138, 2002 | 143 | 2002 |
| Immune checkpoint inhibition in sepsis: a Phase 1b randomized study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of nivolumab RS Hotchkiss, E Colston, S Yende, ED Crouser, GS Martin, T Albertson, ... Intensive care medicine 45, 1360-1371, 2019 | 141 | 2019 |
| A randomized, double-blinded, placebo-controlled pilot trial of anticoagulation in low-risk traumatic brain injury: The Delayed Versus Early Enoxaparin Prophylaxis I (DEEP I) study HA Phelan, SE Wolf, SH Norwood, K Aldy, SC Brakenridge, AL Eastman, ... Journal of Trauma and Acute Care Surgery 73 (6), 1434-1441, 2012 | 127 | 2012 |
| The development of chronic critical illness determines physical function, quality of life, and long-term survival among early survivors of sepsis in surgical ICUs AK Gardner, GL Ghita, Z Wang, T Ozrazgat-Baslanti, SL Raymond, ... Critical care medicine 47 (4), 566-573, 2019 | 126 | 2019 |
| Evidence for persistent immune suppression in patients who develop chronic critical illness after sepsis JA Stortz, TJ Murphy, SL Raymond, JC Mira, R Ungaro, ML Dirain, ... Shock 49 (3), 249-258, 2018 | 124 | 2018 |
| Benchmarking clinical outcomes and the immunocatabolic phenotype of chronic critical illness after sepsis in surgical intensive care unit patients JA Stortz, JC Mira, SL Raymond, TJ Loftus, T Ozrazgat-Baslanti, Z Wang, ... Journal of Trauma and Acute Care Surgery 84 (2), 342-349, 2018 | 112 | 2018 |
| The epidemiology of chronic critical illness after severe traumatic injury at two level–one trauma centers JC Mira, J Cuschieri, T Ozrazgat-Baslanti, Z Wang, GL Ghita, TJ Loftus, ... Critical care medicine 45 (12), 1989-1996, 2017 | 103 | 2017 |
| Persistent inflammation, immunosuppression, and catabolism and the development of chronic critical illness after surgery PA Efron, AM Mohr, A Bihorac, H Horiguchi, MKK Hollen, MS Segal, ... Surgery 164 (2), 178-184, 2018 | 100 | 2018 |
| A protocol for the management of adhesive small bowel obstruction T Loftus, F Moore, E VanZant, T Bala, S Brakenridge, C Croft, ... Journal of Trauma and Acute Care Surgery 78 (1), 13-21, 2015 | 96 | 2015 |
