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Caroline B. Plescia
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SARS-CoV-2 viral budding and entry can be modeled using BSL-2 level virus-like particles
CB Plescia, EA David, D Patra, R Sengupta, S Amiar, Y Su, RV Stahelin
Journal of Biological Chemistry, 2020
832020
Synthesis and biological evaluation of the first triple inhibitors of human topoisomerase 1, tyrosyl–DNA phosphodiesterase 1 (Tdp1), and tyrosyl–DNA phosphodiesterase 2 (Tdp2)
P Wang, MSA Elsayed, CB Plescia, A Ravji, CE Redon, E Kiselev, ...
Journal of medicinal chemistry 60 (8), 3275-3288, 2017
582017
Synthesis and biological evaluation of new fluorinated and chlorinated indenoisoquinoline topoisomerase I poisons
DE Beck, W Lv, M Abdelmalak, CB Plescia, K Agama, C Marchand, ...
Bioorganic & medicinal chemistry 24 (7), 1469-1479, 2016
382016
Synthesis and structure-activity relationship of furoquinolinediones as inhibitors of Tyrosyl-DNA phosphodiesterase 2 (TDP2)
LM Yu, Z Hu, Y Chen, A Ravji, S Lopez, CB Plescia, Q Yu, H Yang, ...
European journal of medicinal chemistry 151, 777-796, 2018
222018
A pyrene-based two-photon excitable fluorescent probe to visualize nuclei in live cells
CS Abeywickrama, KJ Wijesinghe, CB Plescia, LS Fisher, T Goodson, ...
Photochemical & Photobiological Sciences 19, 1152-1159, 2020
202020
Structural effect on the cellular selectivity of an NIR-emitting cyanine probe: from lysosome to simultaneous nucleus and mitochondria selectivity with potential for monitoring …
CS Abeywickrama, KA Bertman, CB Plescia, RV Stahelin, Y Pang
ACS Applied Bio Materials 2 (11), 5174-5181, 2019
182019
Phosphatidylserine clustering by the Ebola virus matrix protein is a critical step in viral budding
ML Husby, S Amiar, LI Prugar, EA David, CB Plescia, KE Huie, ...
EMBO reports 23 (11), e51709, 2022
132022
The first DEP domain of the RhoGEF P-Rex1 autoinhibits activity and contributes to membrane binding
SK Ravala, JB Hopkins, CB Plescia, SR Allgood, MA Kane, JN Cash, ...
Journal of Biological Chemistry 295 (36), 12635-12647, 2020
122020
Evaluation of phenol-substituted diphyllin derivatives as selective antagonists for ebola virus entry
CB Plescia, AR Lindstrom, MV Quintero, P Keiser, M Anantpadma, ...
ACS infectious diseases 8 (5), 942-957, 2022
92022
Characterization of the relationship between the chaperone and lipid-binding functions of the 70-kDa heat-shock protein, HspA1A
L Smulders, AJ Daniels, CB Plescia, D Berger, RV Stahelin, N Nikolaidis
International journal of molecular sciences 21 (17), 5995, 2020
92020
The Ebola virus matrix protein clusters phosphatidylserine, a critical step in viral budding
ML Husby, S Amiar, LI Prugar, EA David, CB Plescia, KE Huie, ...
BioRxiv, 2021.06. 08.447555, 2021
42021
Evaluation of Potency and Metabolic Stability of Diphyllin-derived Vacuolar-ATPase Inhibitors
LM Sanford, P Keiser, N Fujii, H Woods, C Zhang, Z Xu, NS Mahajani, ...
European Journal of Medicinal Chemistry, 116537, 2024
2024
Modeling the Molecular Biology of Infection & Anti-Viral Activity of Small Molecules for Ebola Virus & SARS-CoV-2 using Virus-Like Particles
CB Plescia
Purdue University Graduate School, 2022
2022
SARS-CoV-2 viral budding and entry can be modeled using virus-like particles (preprint)
CB Plescia, EA David, D Patra, R Sengupta, S Amiar, Y Su, RV Stahelin, ...
2020
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