| Lysosomal dysfunction in Down syndrome is APP-dependent and mediated by APP-βCTF (C99) Y Jiang, Y Sato, E Im, M Berg, M Bordi, S Darji, A Kumar, PS Mohan, ... Journal of Neuroscience 39 (27), 5255-5268, 2019 | 114 | 2019 |
| mTOR hyperactivation in Down Syndrome underlies deficits in autophagy induction, autophagosome formation, and mitophagy M Bordi, S Darji, Y Sato, M Mellén, MJ Berg, A Kumar, Y Jiang, RA Nixon Cell Death and Disease 10 (2019), 2019 | 78 | 2019 |
| Endosomal dysfunction induced by directly overactivating Rab5 recapitulates prodromal and neurodegenerative features of Alzheimer’s disease A Pensalfini, S Kim, S Subbanna, C Bleiwas, CN Goulbourne, ... Cell reports 33 (8), 2020 | 72 | 2020 |
| Efficacy of ginger on intraoperative and postoperative nausea and vomiting in elective cesarean section patients A Kalava, SJ Darji, A Kalstein, JM Yarmush, J SchianodiCola, J Weinberg European Journal of Obstetrics & Gynecology and Reproductive Biology 169 (2 …, 2013 | 69 | 2013 |
| Impact of regional versus general anesthesia on the clinical outcomes of patients undergoing major lower extremity amputation J Chery, E Semaan, S Darji, WT Briggs, J Yarmush, M D’Ayala Annals of vascular surgery 28 (5), 1149-1156, 2014 | 56 | 2014 |
| Neurofilament light interaction with GluN1 modulates neurotransmission and schizophrenia-associated behaviors A Yuan, Veeranna, H Sershen, BS Basavarajappa, JF Smiley, A Hashim, ... Translational psychiatry 8 (1), 167, 2018 | 39 | 2018 |
| β2-adrenergic agonists rescue lysosome acidification and function in PSEN1 deficiency by reversing defective ER-to-lysosome delivery of ClC-7 JH Lee, DM Wolfe, S Darji, MK McBrayer, DJ Colacurcio, A Kumar, ... Journal of molecular biology 432 (8), 2633-2650, 2020 | 23 | 2020 |
| Preclinical and randomized clinical evaluation of the p38α kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration Y Jiang, JJ Alam, SN Gomperts, P Maruff, AW Lemstra, UA Germann, ... Nature communications 13 (1), 5308, 2022 | 20 | 2022 |
| HV1 acts as a sodium sensor and promotes superoxide production in medullary thick ascending limb of Dahl salt-sensitive rats C Jin, J Sun, CA Stilphen, SME Smith, H Ocasio, B Bermingham, S Darji, ... Hypertension 64 (3), 541-550, 2014 | 20 | 2014 |
| Autophagy is a novel pathway for neurofilament protein degradation in vivo MV Rao, S Darji, PH Stavrides, CN Goulbourne, A Kumar, DS Yang, ... Autophagy, 2022 | 14 | 2022 |
| Lysosomal dysfunction in Down syndrome and Alzheimer mouse models is caused by v-ATPase inhibition by Tyr682-phosphorylated APP βCTF E Im, Y Jiang, PH Stavrides, S Darji, H Erdjument-Bromage, TA Neubert, ... Science Advances 9 (30), eadg1925, 2023 | 12 | 2023 |
| Lysosomal dysfunction in Down Syndrome and Alzheimer mouse models is caused by selective v-ATPase inhibition by Tyr682 phosphorylated APP βCTF E Im, Y Jiang, P Stavrides, S Darji, H Erdjument-Bromage, TA Neubert, ... bioRxiv, 2022.06. 02.494546, 2022 | 6 | 2022 |
| P4‐692: EFFECTS OF P38α MAP KINASE INHIBITION ON THE NEURODEGENERATIVE PHENOTYPE OF THE TS2 DOWN SYNDROME MOUSE MODEL Y Jiang, P Stavrides, S Darji, DS Yang, C Bleiwas, J Smiley, U Germann, ... Alzheimer's & Dementia 15, P1597-P1597, 2019 | 4 | 2019 |
Paul M. O'ConnorAugusta UniversityVerified email at augusta.edu
