James Posada
James Posada
Resolve Therapeutics
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Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro
J Posada, N Yew, NG Ahn, GFV Woude, JA Cooper
Molecular and cellular biology, 1993
Purification and characterization of mitogen-activated protein kinase activator (s) from epidermal growth factor-stimulated A431 cells.
R Seger, NG Ahn, J Posada, ES Munar, AM Jensen, JA Cooper, MH Cobb, ...
Journal of Biological Chemistry 267 (20), 14373-14381, 1992
Requirements for phosphorylation of MAP kinase during meiosis in Xenopus oocytes
J Posada, JA Cooper
Science 255 (5041), 212-215, 1992
Asbestos causes stimulation of the extracellular signal-regulated kinase 1 mitogen-activated protein kinase cascade after phosphorylation of the epidermal growth factor receptor
CL Zanella, J Posada, TR Tritton, BT Mossman
Cancer research 56 (23), 5334-5338, 1996
Tyrosine phosphorylation and activation of homologous protein kinases during oocyte maturation and mitogenic activation of fibroblasts
J Posada, J Sanghera, S Pelech, R Aebersold, JA Cooper
Molecular and cellular biology, 1991
p42 mitogen-activated protein kinase in brain: prominent localization in neuronal cell bodies and dendrites
RS Fiore, VE Bayer, SL Pelech, J Posada, JA Cooper, JM Baraban
Neuroscience 55 (2), 463-472, 1993
JNK, but not MAPK, activation is associated with Fas‐mediated apoptosis in human T cells
DJ Wilson, KA Fortner, DH Lynch, RR Mattingly, IG Macara, JA Posada, ...
European journal of immunology 26 (5), 989-994, 1996
The Seven-transmembrane-spanning Receptors for Endothelin and Thrombin Cause Proliferation of Airway Smooth Muscle Cells and Activation of the Extracellular Regulated Kinase …
PS Shapiro, JN Evans, RJ Davis, JA Posada
Journal of Biological Chemistry 271 (10), 5750-5754, 1996
Inhibition of ERK activation attenuates endothelin-stimulated airway smooth muscle cell proliferation.
A Whelchel, J Evans, J Posada
American journal of respiratory cell and molecular biology 16 (5), 589-596, 1997
Phosphorylation of mitogen-activated protein kinases is involved in the epidermal growth factor and phorbol ester, but not in the thyrotropin/cAMP, thyroid mitogenic pathway.
F Lamy, F Wilkin, M Baptist, J Posada, PP Roger, JE Dumont
Journal of Biological Chemistry 268 (12), 8398-8401, 1993
Molecular signal integration. Interplay between serine, threonine, and tyrosine phosphorylation.
J Posada, JA Cooper
Molecular biology of the cell 3 (6), 583-592, 1992
Protein kinase C in adriamycin action and resistance in mouse sarcoma 180 cells
J Posada, P Vichi, TR Tritton
Cancer research 49 (23), 6634-6639, 1989
Human multidrug resistant KB cells overexpress protein kinase C: involvement in drug resistance.
JA Posada, EM McKeegan, KF Worthington, MJ Morin, S Jaken, TR Tritton
Cancer communications 1 (5), 285-292, 1989
Activation of multiple mitogen-activated protein kinase signal transduction pathways by the endothelin B receptor requires the cytoplasmic tail
E Aquilla, A Whelchel, HJ Knot, M Nelson, J Posada
Journal of Biological Chemistry 271 (49), 31572-31579, 1996
Improvement of severe fatigue following nuclease therapy in patients with primary Sjögren’s syndrome: a randomized clinical trial
J Posada, S Valadkhan, D Burge, K Davies, J Tarn, J Casement, ...
Arthritis & Rheumatology 73 (1), 143-150, 2021
Safety, pharmacokinetics, and pharmacodynamics of RSLV-132, an RNase-Fc fusion protein in systemic lupus erythematosus: a randomized, double-blind, placebo-controlled study
DJ Burge, J Eisenman, K Byrnes-Blake, P Smolak, K Lau, SB Cohen, ...
Lupus 26 (8), 825-834, 2017
Asbestos causes stimulation of the ERK-1 mitogen-activated protein kinase cascade after phosphorylation of the epidermal growth factor receptor
C Zanella, J Posada, T Tritton, B Mossman
Cancer Res 56, 5334-5338, 1996
Endothelin-stimulated ERK activation in airway smooth-muscle cells requires calcium influx and Raf activation
P Vichi, A Whelchel, H Knot, M Nelson, W Kolch, J Posada
American journal of respiratory cell and molecular biology 20 (1), 99-105, 1999
Blood-borne RNA correlates with disease activity and IFN-stimulated gene expression in systemic lupus erythematosus
JR Doedens, WD Jones, K Hill, MJ Mason, VH Gersuk, PJ Mease, ...
The Journal of Immunology 197 (7), 2854-2863, 2016
Therapeutic nuclease-albumin fusions and methods
JA Posada, C Gabel
US Patent 10,988,745, 2021
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