Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro J Posada, N Yew, NG Ahn, GFV Woude, JA Cooper Molecular and cellular biology, 1993 | 494 | 1993 |
Purification and characterization of mitogen-activated protein kinase activator (s) from epidermal growth factor-stimulated A431 cells. R Seger, NG Ahn, J Posada, ES Munar, AM Jensen, JA Cooper, MH Cobb, ... Journal of Biological Chemistry 267 (20), 14373-14381, 1992 | 492 | 1992 |
Requirements for phosphorylation of MAP kinase during meiosis in Xenopus oocytes J Posada, JA Cooper Science 255 (5041), 212-215, 1992 | 369 | 1992 |
Asbestos causes stimulation of the extracellular signal-regulated kinase 1 mitogen-activated protein kinase cascade after phosphorylation of the epidermal growth factor receptor CL Zanella, J Posada, TR Tritton, BT Mossman Cancer research 56 (23), 5334-5338, 1996 | 258 | 1996 |
Tyrosine phosphorylation and activation of homologous protein kinases during oocyte maturation and mitogenic activation of fibroblasts J Posada, J Sanghera, S Pelech, R Aebersold, JA Cooper Molecular and cellular biology 11 (5), 2517-2528, 1991 | 234 | 1991 |
p42 mitogen-activated protein kinase in brain: prominent localization in neuronal cell bodies and dendrites RS Fiore, VE Bayer, SL Pelech, J Posada, JA Cooper, JM Baraban Neuroscience 55 (2), 463-472, 1993 | 212 | 1993 |
JNK, but not MAPK, activation is associated with Fas‐mediated apoptosis in human T cells DJ Wilson, KA Fortner, DH Lynch, RR Mattingly, IG Macara, JA Posada, ... European journal of immunology 26 (5), 989-994, 1996 | 180 | 1996 |
The Seven-transmembrane-spanning Receptors for Endothelin and Thrombin Cause Proliferation of Airway Smooth Muscle Cells and Activation of the Extracellular Regulated Kinase … PS Shapiro, JN Evans, RJ Davis, JA Posada Journal of Biological Chemistry 271 (10), 5750-5754, 1996 | 139 | 1996 |
Inhibition of ERK activation attenuates endothelin-stimulated airway smooth muscle cell proliferation. A Whelchel, J Evans, J Posada American journal of respiratory cell and molecular biology 16 (5), 589-596, 1997 | 134 | 1997 |
Phosphorylation of mitogen-activated protein kinases is involved in the epidermal growth factor and phorbol ester, but not in the thyrotropin/cAMP, thyroid mitogenic pathway. F Lamy, F Wilkin, M Baptist, J Posada, PP Roger, JE Dumont Journal of Biological Chemistry 268 (12), 8398-8401, 1993 | 128 | 1993 |
Molecular signal integration. Interplay between serine, threonine, and tyrosine phosphorylation. J Posada, JA Cooper Molecular biology of the cell 3 (6), 583-592, 1992 | 127 | 1992 |
Protein kinase C in adriamycin action and resistance in mouse sarcoma 180 cells J Posada, P Vichi, TR Tritton Cancer research 49 (23), 6634-6639, 1989 | 118 | 1989 |
Human multidrug resistant KB cells overexpress protein kinase C: involvement in drug resistance. JA Posada, EM McKeegan, KF Worthington, MJ Morin, S Jaken, TR Tritton Cancer communications 1 (5), 285-292, 1989 | 97 | 1989 |
Improvement of severe fatigue following nuclease therapy in patients with primary Sjögren’s syndrome: a randomized clinical trial J Posada, S Valadkhan, D Burge, K Davies, J Tarn, J Casement, ... Arthritis & Rheumatology 73 (1), 143-150, 2021 | 55 | 2021 |
Activation of multiple mitogen-activated protein kinase signal transduction pathways by the endothelin B receptor requires the cytoplasmic tail E Aquilla, A Whelchel, HJ Knot, M Nelson, J Posada Journal of Biological Chemistry 271 (49), 31572-31579, 1996 | 53 | 1996 |
Safety, pharmacokinetics, and pharmacodynamics of RSLV-132, an RNase-Fc fusion protein in systemic lupus erythematosus: a randomized, double-blind, placebo-controlled study DJ Burge, J Eisenman, K Byrnes-Blake, P Smolak, K Lau, SB Cohen, ... Lupus 26 (8), 825-834, 2017 | 44 | 2017 |
Asbestos causes stimulation of the ERK-1 mitogen-activated protein kinase cascade after phosphorylation of the epidermal growth factor receptor C Zanella, J Posada, T Tritton, B Mossman Cancer Res 56, 5334-5338, 1996 | 38 | 1996 |
Endothelin-stimulated ERK activation in airway smooth-muscle cells requires calcium influx and Raf activation P Vichi, A Whelchel, H Knot, M Nelson, W Kolch, J Posada American journal of respiratory cell and molecular biology 20 (1), 99-105, 1999 | 33 | 1999 |
Blood-borne RNA correlates with disease activity and IFN-stimulated gene expression in systemic lupus erythematosus JR Doedens, WD Jones, K Hill, MJ Mason, VH Gersuk, PJ Mease, ... The Journal of Immunology 197 (7), 2854-2863, 2016 | 21 | 2016 |
Therapeutic nuclease-albumin fusions and methods JA Posada, C Gabel US Patent 10,988,745, 2021 | 16 | 2021 |