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Avik Roy, PhD
Avik Roy, PhD
CSO Simmaron Research INC. Professor (adj) at Chemistry & Biochemistry at UWM
Verified email at uwm.edu - Homepage
Title
Cited by
Cited by
Year
Selective inhibition of NF-κB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease
A Ghosh, A Roy, X Liu, JH Kordower, EJ Mufson, DM Hartley, S Ghosh, ...
Proceedings of the National Academy of Sciences 104 (47), 18754-18759, 2007
5152007
Up-regulation of microglial CD11b expression by nitric oxide
A Roy, YK Fung, X Liu, K Pahan
Journal of Biological Chemistry 281 (21), 14971-14980, 2006
2332006
Chronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's disease
HB Dodiya, CB Forsyth, RM Voigt, PA Engen, J Patel, M Shaikh, SJ Green, ...
Neurobiology of disease 135, 104352, 2020
2322020
Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease
A Ghosh, A Roy, J Matras, S Brahmachari, HE Gendelman, K Pahan
Journal of Neuroscience 29 (43), 13543-13556, 2009
2012009
Regulation of cyclic AMP response element binding and hippocampal plasticity-related genes by peroxisome proliferator-activated receptor α
A Roy, M Jana, GT Corbett, S Ramaswamy, JH Kordower, FJ Gonzalez, ...
Cell reports 4 (4), 724-737, 2013
1712013
HMG-CoA reductase inhibitors bind to PPARα to upregulate neurotrophin expression in the brain and improve memory in mice
A Roy, M Jana, M Kundu, GT Corbett, SB Rangaswamy, RK Mishra, ...
Cell metabolism 22 (2), 253-265, 2015
1632015
Reactive oxygen species up-regulate CD11b in microglia via nitric oxide: Implications for neurodegenerative diseases
A Roy, A Jana, K Yatish, MB Freidt, YK Fung, JA Martinson, K Pahan
Free Radical Biology and Medicine 45 (5), 686-699, 2008
1492008
Up-Regulation of Neurotrophic Factors by Cinnamon and its Metabolite Sodium Benzoate: Therapeutic Implications for Neurodegenerative Disorders
A Jana, KK Modi, A Roy, JA Anderson, RB van Breemen, K Pahan
Journal of Neuroimmune Pharmacology, 1-17, 2013
1452013
Sodium Phenylbutyrate Controls Neuroinflammatory and Antioxidant Activities and Protects Dopaminergic Neurons in Mouse Models of Parkinson’s Disease
A Roy, A Ghosh, A Jana, X Liu, S Brahmachari, HE Gendelman, K Pahan
PLoS ONE 7 (6), e38113, 2012
1402012
Suppression of nuclear factor-kappa B activation and inflammation in microglia by a physically-modified saline
S Khasnavis, A Jana, A Roy, T Wood, S Ghosh, R Watson, K Pahan
Journal of Biological Chemistry, 2012
1242012
Cinnamic acid activates PPARα to stimulate Lysosomal biogenesis and lower Amyloid plaque pathology in an Alzheimer's disease mouse model
S Chandra, A Roy, M Jana, K Pahan
Neurobiology of disease 124, 379-395, 2019
1162019
Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer’s pathology
SB Rangasamy, M Jana, A Roy, GT Corbett, M Kundu, S Chandra, ...
The Journal of Clinical Investigation 128 (10), 4297-4312, 2018
1162018
Gemfibrozil ameliorates relapsing-remitting experimental autoimmune encephalomyelitis independent of peroxisome proliferator-activated receptor-α
S Dasgupta, A Roy, M Jana, DM Hartley, K Pahan
Molecular pharmacology 72 (4), 934-946, 2007
1132007
Cinnamon and Its Metabolite Sodium Benzoate Attenuate the Activation of p21rac and Protect Memory and Learning in an Animal Model of Alzheimer’s Disease
KK Modi, A Roy, S Brahmachari, SB Rangasamy, K Pahan
PloS one 10 (6), e0130398, 2015
1092015
Prospects of statins in Parkinson disease
A Roy, K Pahan
The Neuroscientist 17 (3), 244-255, 2011
1092011
Selective targeting of the TLR2/MyD88/NF-κB pathway reduces α-synuclein spreading in vitro and in vivo
D Dutta, M Jana, M Majumder, S Mondal, A Roy, K Pahan
Nature communications 12 (1), 5382, 2021
1002021
Gemfibrozil, stretching arms beyond lipid lowering
A Roy, K Pahan
Immunopharmacology and immunotoxicology 31 (3), 339-351, 2009
922009
Neutralization of RANTES and eotaxin prevents the loss of dopaminergic neurons in a mouse model of Parkinson disease
G Chandra, SB Rangasamy, A Roy, JH Kordower, K Pahan
Journal of Biological Chemistry 291 (29), 15267-15281, 2016
862016
Identification and characterization of PPARα ligands in the hippocampus
A Roy, M Kundu, M Jana, RK Mishra, Y Yung, CH Luan, FJ Gonzalez, ...
Nature chemical biology 12 (12), 1075-1083, 2016
792016
Aspirin binds to PPARα to stimulate hippocampal plasticity and protect memory
D Patel, A Roy, M Kundu, M Jana, CH Luan, FJ Gonzalez, K Pahan
Proceedings of the National Academy of Sciences 115 (31), E7408-E7417, 2018
782018
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