| Landscape and function of multiple mutations within individual oncogenes Y Saito, J Koya, M Araki, Y Kogure, S Shingaki, M Tabata, MB McClure, ... Nature 582 (7810), 95-99, 2020 | 100 | 2020 |
| Structure-Based de Novo Molecular Generator Combined with Artificial Intelligence and Docking Simulations B Ma, K Terayama, S Matsumoto, Y Isaka, Y Sasakura, H Iwata, M Araki, ... Journal of Chemical Information and Modeling 61 (7), 3304-3313, 2021 | 42 | 2021 |
| Exploring ligand binding pathways on proteins using hypersound-accelerated molecular dynamics M Araki, S Matsumoto, GJ Bekker, Y Isaka, Y Sagae, N Kamiya, Y Okuno Nature Communications 12 (1), 2793, 2021 | 29 | 2021 |
| Rotation mechanism of molecular motor V1-ATPase studied by multiscale molecular dynamics simulation Y Isaka, T Ekimoto, Y Kokabu, I Yamato, T Murata, M Ikeguchi Biophysical journal 112 (5), 911-920, 2017 | 15 | 2017 |
| Improvement in predicting drug sensitivity changes associated with protein mutations using a molecular dynamics based alchemical mutation method F Ono, S Chiba, Y Isaka, S Matsumoto, B Ma, R Katayama, M Araki, ... Scientific reports 10 (1), 2161, 2020 | 10 | 2020 |
| E487K-Induced Disorder in Functionally Relevant Dynamics of Mitochondrial Aldehyde Dehydrogenase 2 S Matsumoto, M Araki, Y Isaka, F Ono, K Hirohashi, S Ohashi, M Muto, ... Biophysical Journal 119 (3), 628-637, 2020 | 4 | 2020 |
| Coarse-Grained Diffraction Template Matching Model to Retrieve Multiconformational Models for Biomolecule Structures from Noisy Diffraction Patterns A Tokuhisa, R Kanada, S Chiba, K Terayama, Y Isaka, B Ma, N Kamiya, ... Journal of Chemical Information and Modeling 60 (6), 2803-2818, 2020 | 4 | 2020 |
| Integrated approach to functional analysis of an ERBB2 variant of unknown significance detected by a cancer gene panel test Y Harada, A Sato, M Araki, S Matsumoto, Y Isaka, Y Sagae, T Abe, ... Cellular Oncology 45 (1), 121-134, 2022 | 2 | 2022 |
| LTK mutations responsible for resistance to lorlatinib in non-small cell lung cancer harboring CLIP1-LTK fusion S Mori, H Izumi, M Araki, J Liu, Y Tanaka, Y Kagawa, Y Sagae, B Ma, ... Communications Biology 7 (1), 412, 2024 | | 2024 |
| Molecular dynamics unveils multiple-site binding of inhibitors with reduced activity on the surface of dihydrofolate reductase M Araki, T Ekimoto, K Takemura, S Matsumoto, Y Tamura, H Kokubo, ... bioRxiv, 2024.03. 27.586990, 2024 | | 2024 |
| 3P160 Rotation mechanism of V1-ATPase studied by MD simulation (Molecular motor, Poster, The 52th Annual Meeting of the Biophysical Society of Japan (BSJ2014)) I Yuta, M Takeshi, I Mitsunori Seibutsu Butsuri 54 (supplement1-2), S275, 2014 | | 2014 |
| 1P144 Course-grained molecular dynamics simulation of V1-ATPase (11. Molecular motor, Poster, The 52nd Annual Meeting of the Biophysical Society of Japan (BSJ2014)) H Kashimura, Y Isaka, Y Kokabu, M Ikeguchi Seibutsu Butsuri 54 (supplement1-2), S164, 2014 | | 2014 |
| 3P160 MD シミュレーションによる Enterococcus hirae. V_1-ATPase の回転機構の解明 (分子モーター, ポスター, 第 52 回日本生物物理学会年会 (2014 年度)) I Yuta, M Takeshi, I Mitsunori 生物物理 54 (1), S275, 2014 | | 2014 |
| 1P144 V1-ATPase の粗視化分子動力学シミュレーション (11. 分子モーター, ポスター, 第 52 回日本生物物理学会年会 (2014 年度)) H Kashimura, Y Isaka, Y Kokabu, M Ikeguchi 生物物理 54 (1), S164, 2014 | | 2014 |
| 3P165 Rotation mechanism of V_1-ATPase studied by steered MD simulations (11. Molecular motor, Poster) Y Isaka, I Yamato, T Murata, M Ikeguchi Seibutsu Butsuri 53 (supplement1-2), S239, 2013 | | 2013 |
| 3P165 腸球菌由来 V_1ATPase の軸強制回転シミュレーションによる回転機構の解明 (11. 分子モーター, ポスター, 日本生物物理学会年会第 51 回 (2013 年度)) Y Isaka, I Yamato, T Murata, M Ikeguchi 生物物理 53 (1), S239, 2013 | | 2013 |
Biao MaRIKEN Center for Computational Science(2021-)Verified email at riken.jp
