| Activation of the MAP kinase pathway by the protein kinase raf LR Howe, SJ Leevers, N Gómez, S Nakielny, P Cohen, CJ Marshall Cell 71 (2), 335-342, 1992 | 1014 | 1992 |
| Cyclo-oxygenase 2: a pharmacological target for the prevention of cancer AJ Dannenberg, NK Altorki, JO Boyle, C Dang, LR Howe, BB Weksler, ... The lancet oncology 2 (9), 544-551, 2001 | 818 | 2001 |
| Cyclooxygenase-2: a target for the prevention and treatment of breast cancer. LR Howe, K Subbaramaiah, AM Brown, AJ Dannenberg Endocrine-related cancer 8 (2), 97-114, 2001 | 456 | 2001 |
| Wnt signaling and breast cancer LR Howe, AMC Brown Cancer Biology and Therapy 3 (1), 36-41, 2004 | 454 | 2004 |
| Inflammation and breast cancer. Cyclooxygenase/prostaglandin signaling and breast cancer LR Howe Breast Cancer Research 9 (4), 210, 2007 | 397 | 2007 |
| Molecular pathways: adipose inflammation as a mediator of obesity-associated cancer LR Howe, K Subbaramaiah, CA Hudis, AJ Dannenberg Clinical Cancer Research 19 (22), 6074-6083, 2013 | 367 | 2013 |
| Twist is up-regulated in response to Wnt1 and inhibits mouse mammary cell differentiation LR Howe, O Watanabe, J Leonard, AMC Brown Cancer research 63 (8), 1906-1913, 2003 | 313 | 2003 |
| Lysophosphatidic acid stimulates mitogen-activated protein kinase activation via a G-protein-coupled pathway requiring p21ras and p74raf-1. LR Howe, CJ Marshall Journal of Biological Chemistry 268 (28), 20717-20720, 1993 | 302 | 1993 |
| Transcriptional Activation of Cyclooxygenase-2in Wnt-1-transformed Mouse Mammary Epithelial Cells LR Howe, K Subbaramaiah, WJ Chung, AJ Dannenberg, AMC Brown Cancer research 59 (7), 1572-1577, 1999 | 263 | 1999 |
| Celecoxib, a selective cyclooxygenase 2 inhibitor, protects against human epidermal growth factor receptor 2 (HER-2)/neu-induced breast cancer LR Howe, K Subbaramaiah, J Patel, JL Masferrer, A Deora, C Hudis, ... Cancer research 62 (19), 5405-5407, 2002 | 259 | 2002 |
| HER2/neu-induced mammary tumorigenesis and angiogenesis are reduced in cyclooxygenase-2 knockout mice LR Howe, SH Chang, KC Tolle, R Dillon, LJT Young, RD Cardiff, ... Cancer research 65 (21), 10113-10119, 2005 | 200 | 2005 |
| A dominant-negative mutant of raf blocks mitogen-activated protein kinase activation by growth factors and oncogenic p21ras. D Schaap, J van der Wal, LR Howe, CJ Marshall, WJ van Blitterswijk Journal of Biological Chemistry 268 (27), 20232-20236, 1993 | 194 | 1993 |
| A role for cyclooxygenase-2 inhibitors in the prevention and treatment of cancer LR Howe, AJ Dannenberg Seminars in oncology 29 (3), 111-119, 2002 | 187 | 2002 |
| Systemic Correlates of White Adipose Tissue Inflammation in Early-Stage Breast Cancer NM Iyengar, XK Zhou, A Gucalp, PG Morris, LR Howe, DD Giri, M Morrow, ... Clinical Cancer Research 22 (9), 2283-2289, 2016 | 186 | 2016 |
| PEA3 is up-regulated in response to Wnt1 and activates the expression of cyclooxygenase-2 LR Howe, HC Crawford, K Subbaramaiah, JA Hassell, AJ Dannenberg, ... Journal of Biological Chemistry 276 (23), 20108-20115, 2001 | 169 | 2001 |
| Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize β-catenin independently of Frizzled proteins K Brennan, JM Gonzalez-Sancho, LA Castelo-Soccio, LR Howe, ... Oncogene 23 (28), 4873-4884, 2004 | 131 | 2004 |
| Identification of PADI2 as a potential breast cancer biomarker and therapeutic target JL McElwee, S Mohanan, OL Griffith, HC Breuer, LJ Anguish, ... BMC cancer 12 (1), 500, 2012 | 125 | 2012 |
| Multiple kinases mediate T-cell-receptor signalling LR Howe, A Weiss Trends in biochemical sciences 20 (2), 59-64, 1995 | 120 | 1995 |
| HER-2/neu status is a determinant of mammary aromatase activity in vivo: evidence for a cyclooxygenase-2-dependent mechanism K Subbaramaiah, LR Howe, ER Port, E Brogi, J Fishman, CH Liu, T Hla, ... Cancer research 66 (10), 5504-5511, 2006 | 118 | 2006 |
| Targeting the HER/EGFR/ErbB family to prevent breast cancer LR Howe, PH Brown Cancer prevention research 4 (8), 1149-1157, 2011 | 111 | 2011 |
