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Paul W A Devine
Paul W A Devine
Verified email at medimmune.com
Title
Cited by
Cited by
Year
Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo
CL Dobson, PWA Devine, JJ Phillips, DR Higazi, C Lloyd, B Popovic, ...
Scientific reports 6 (1), 38644, 2016
1142016
Skp is a multivalent chaperone of outer-membrane proteins
B Schiffrin, AN Calabrese, PWA Devine, SA Harris, AE Ashcroft, ...
Nature structural & molecular biology 23 (9), 786-793, 2016
1002016
Investigating the structural compaction of biomolecules upon transition to the gas-phase using ESI-TWIMS-MS
PWA Devine, HC Fisher, AN Calabrese, F Whelan, DR Higazi, JR Potts, ...
Journal of the American Society for Mass Spectrometry 28 (9), 1855-1862, 2017
622017
An in vivo platform to select and evolve aggregation-resistant proteins
JS Ebo, JC Saunders, PWA Devine, AM Gordon, AS Warwick, B Schiffrin, ...
Nature communications 11 (1), 1816, 2020
262020
Mechanistic insights into the rational design of masked antibodies
CT Orozco, M Bersellini, LM Irving, WW Howard, D Hargreaves, ...
MAbs 14 (1), 2095701, 2022
62022
Interconversion of Unexpected Thiol States Affects the Stability, Structure, and Dynamics of Antibody Engineered for Site-Specific Conjugation
CT Orozco, MJ Edgeworth, PWA Devine, AR Hines, O Cornwell, ...
Bioconjugate Chemistry 32 (8), 1834-1844, 2021
52021
Antisense oligonucleotide activity in tumour cells is influenced by intracellular LBPA distribution and extracellular vesicle recycling
AN Kapustin, P Davey, D Longmire, C Matthews, E Linnane, N Rustogi, ...
Communications Biology 4 (1), 1241, 2021
42021
Engineered CHO cells as a novel AAV production platform for gene therapy delivery
A Nagy, L Chakrabarti, J Kurasawa, SHR Mulagapati, P Devine, J Therres, ...
Scientific Reports 13 (1), 19210, 2023
32023
Multi-Attribute Monitoring Method for Process Development of Engineered Antibody for Site-Specific Conjugation
AR Hines, M Edgeworth, PWA Devine, S Shepherd, N Chatterton, ...
Journal of the American Society for Mass Spectrometry 34 (7), 1330-1341, 2023
32023
Spectral interferences impede the high-resolution mass analysis of recombinant adeno-associated viruses
V Yin, PWA Devine, JC Saunders, A Hines, S Shepherd, M Dembek, ...
bioRxiv, 2022.08. 27.505551, 2022
32022
Defining the mechanism behind the self-association of therapeutic monoclonal antibodies using mass spectrometric techniques
PWA Devine
University of Leeds, 2016
22016
A Peptide Barcode Based Approach for Efficient in vivo Screening of RNA Delivery Systems
U Odunze, N Rustogi, P Devine, L Miller, S Pereira, S Vashist, H Snijder, ...
12023
Stochastic assembly of biomacromolecular complexes: impact and implications on charge interpretation in native mass spectrometry
V Yin, PWA Devine, JC Saunders, A Barendregt, F Cusdin, A Ristani, ...
Chemical Science 14 (35), 9316-9327, 2023
12023
To 200,000 m/z and beyond: native electron capture charge reduction mass spectrometry deconvolves heterogeneous signals in large biopharmaceutical analytes
KIP Le Huray, TP Woerner, T Moreira, M Reinhardt-Szyba, PWA Devine, ...
bioRxiv, 2024.02. 19.581059, 2024
2024
Interconversion of unexpected thiol states affects stability, structure and dynamics in engineered antibody for site-specific conjugation
CT Orozco, MJ Edgeworth, PWA Devine, AR Hines, O Cornwell, X Wang, ...
bioRxiv, 2020.09. 28.317339, 2020
2020
Data associated with'An in vivo platform to select and evolve aggregation-resistant proteins'
JS Ebo, JC Saunders, PWA Devine, AM Gordon, AS Warwick, B Schiffrin, ...
University of Leeds, 2019
2019
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