Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo CL Dobson, PWA Devine, JJ Phillips, DR Higazi, C Lloyd, B Popovic, ... Scientific reports 6 (1), 38644, 2016 | 114 | 2016 |
Skp is a multivalent chaperone of outer-membrane proteins B Schiffrin, AN Calabrese, PWA Devine, SA Harris, AE Ashcroft, ... Nature structural & molecular biology 23 (9), 786-793, 2016 | 100 | 2016 |
Investigating the structural compaction of biomolecules upon transition to the gas-phase using ESI-TWIMS-MS PWA Devine, HC Fisher, AN Calabrese, F Whelan, DR Higazi, JR Potts, ... Journal of the American Society for Mass Spectrometry 28 (9), 1855-1862, 2017 | 62 | 2017 |
An in vivo platform to select and evolve aggregation-resistant proteins JS Ebo, JC Saunders, PWA Devine, AM Gordon, AS Warwick, B Schiffrin, ... Nature communications 11 (1), 1816, 2020 | 26 | 2020 |
Mechanistic insights into the rational design of masked antibodies CT Orozco, M Bersellini, LM Irving, WW Howard, D Hargreaves, ... MAbs 14 (1), 2095701, 2022 | 6 | 2022 |
Interconversion of Unexpected Thiol States Affects the Stability, Structure, and Dynamics of Antibody Engineered for Site-Specific Conjugation CT Orozco, MJ Edgeworth, PWA Devine, AR Hines, O Cornwell, ... Bioconjugate Chemistry 32 (8), 1834-1844, 2021 | 5 | 2021 |
Antisense oligonucleotide activity in tumour cells is influenced by intracellular LBPA distribution and extracellular vesicle recycling AN Kapustin, P Davey, D Longmire, C Matthews, E Linnane, N Rustogi, ... Communications Biology 4 (1), 1241, 2021 | 4 | 2021 |
Engineered CHO cells as a novel AAV production platform for gene therapy delivery A Nagy, L Chakrabarti, J Kurasawa, SHR Mulagapati, P Devine, J Therres, ... Scientific Reports 13 (1), 19210, 2023 | 3 | 2023 |
Multi-Attribute Monitoring Method for Process Development of Engineered Antibody for Site-Specific Conjugation AR Hines, M Edgeworth, PWA Devine, S Shepherd, N Chatterton, ... Journal of the American Society for Mass Spectrometry 34 (7), 1330-1341, 2023 | 3 | 2023 |
Spectral interferences impede the high-resolution mass analysis of recombinant adeno-associated viruses V Yin, PWA Devine, JC Saunders, A Hines, S Shepherd, M Dembek, ... bioRxiv, 2022.08. 27.505551, 2022 | 3 | 2022 |
Defining the mechanism behind the self-association of therapeutic monoclonal antibodies using mass spectrometric techniques PWA Devine University of Leeds, 2016 | 2 | 2016 |
A Peptide Barcode Based Approach for Efficient in vivo Screening of RNA Delivery Systems U Odunze, N Rustogi, P Devine, L Miller, S Pereira, S Vashist, H Snijder, ... | 1 | 2023 |
Stochastic assembly of biomacromolecular complexes: impact and implications on charge interpretation in native mass spectrometry V Yin, PWA Devine, JC Saunders, A Barendregt, F Cusdin, A Ristani, ... Chemical Science 14 (35), 9316-9327, 2023 | 1 | 2023 |
To 200,000 m/z and beyond: native electron capture charge reduction mass spectrometry deconvolves heterogeneous signals in large biopharmaceutical analytes KIP Le Huray, TP Woerner, T Moreira, M Reinhardt-Szyba, PWA Devine, ... bioRxiv, 2024.02. 19.581059, 2024 | | 2024 |
Interconversion of unexpected thiol states affects stability, structure and dynamics in engineered antibody for site-specific conjugation CT Orozco, MJ Edgeworth, PWA Devine, AR Hines, O Cornwell, X Wang, ... bioRxiv, 2020.09. 28.317339, 2020 | | 2020 |
Data associated with'An in vivo platform to select and evolve aggregation-resistant proteins' JS Ebo, JC Saunders, PWA Devine, AM Gordon, AS Warwick, B Schiffrin, ... University of Leeds, 2019 | | 2019 |