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Dr. Iago de Castro Silva
Dr. Iago de Castro Silva
Verified email at med.miami.edu
Title
Cited by
Cited by
Year
Combined MEK and STAT3 inhibition uncovers stromal plasticity by enriching for cancer-associated fibroblasts with mesenchymal stem cell-like features to overcome immunotherapy …
J Datta, X Dai, A Bianchi, IDC Silva, S Mehra, VT Garrido, P Lamichhane, ...
Gastroenterology 163 (6), 1593-1612, 2022
552022
Targeting tumor–stromal IL6/STAT3 signaling through IL1 receptor inhibition in pancreatic Cancer
AR Dosch, S Singh, X Dai, S Mehra, IDC Silva, A Bianchi, S Srinivasan, ...
Molecular cancer therapeutics 20 (11), 2280-2290, 2021
282021
Cell-autonomous Cxcl1 sustains tolerogenic circuitries and stromal inflammation via neutrophil-derived TNF in pancreatic cancer
A Bianchi, I De Castro Silva, NU Deshpande, S Singh, S Mehra, ...
Cancer discovery 13 (6), 1428-1453, 2023
252023
Distinct mechanisms of innate and adaptive immune regulation underlie poor oncologic outcomes associated with KRAS-TP53 co-alteration in pancreatic cancer
J Datta, A Bianchi, I De Castro Silva, NU Deshpande, LL Cao, S Mehra, ...
Oncogene 41 (28), 3640-3654, 2022
182022
Neutrophil-mediated fibroblast-tumor cell il-6/stat-3 signaling underlies the association between neutrophil-to-lymphocyte ratio dynamics and chemotherapy response in localized …
I de Castro Silva, A Bianchi, NU Deshpande, P Sharma, S Mehra, ...
Elife 11, e78921, 2022
152022
Urolithin A attenuates severity of chronic pancreatitis associated with continued alcohol intake by inhibiting PI3K/AKT/mTOR signaling
S Mehra, S Srinivasan, S Singh, Z Zhou, V Garrido, IDC Silva, TM Totiger, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 323 (4 …, 2022
102022
Stalled at the intersection: insurance status and disparities in post-mastectomy breast reconstruction
O Friedman-Eldar, J Burke, I de Castro Silva, CC Baumrucker, F Valle, ...
Breast cancer research and treatment 194 (2), 327-335, 2022
62022
Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers
AR Dosch, WK Chatila, Y Ban, A Bianchi, NU Deshpande, IDC Silva, ...
Oncotarget 12 (20), 2104, 2021
52021
Racial disparity in pathologic response following neoadjuvant chemotherapy in resected pancreatic cancer: a multi-institutional analysis from the Central Pancreatic Consortium
I Ogobuiro, AL Collier, K Khan, I de Castro Silva, D Kwon, GC Wilson, ...
Annals of surgical oncology 30 (3), 1485-1494, 2023
42023
Remodeling of stromal immune microenvironment by urolithin A improves survival with immune checkpoint blockade in pancreatic cancer
S Mehra, VT Garrido, AR Dosch, P Lamichhane, S Srinivasan, SP Singh, ...
Cancer research communications 3 (7), 1224-1236, 2023
22023
Persistent and interdependent: Racial disparities and their mechanisms in postmastectomy breast reconstruction
J Burke, O Friedman-Eldar, G Halfteck, I de Castro Silva, CC Baumrucker, ...
Surgery 172 (1), 25-30, 2022
22022
Combined MEK and STAT3 inhibition reprograms stromal inflammation to overcome immunotherapy resistance in pancreatic cancer
J Datta, X Dai, A Bianchi, I De Castro Silva, S Mehra, V Garrido, ...
bioRxiv, 2021.03. 07.434236, 2021
22021
Rechallenge with combination ipilimumab and anti-PD-1 (IPI+ PD1) in metastatic melanoma after acquired resistance to IPI+ PD1 immunotherapy
A Hepner, MS Carlino, DB Johnson, CL Gérard, S Lo, L Pallan, ID Silva, ...
Annals of Oncology 30, v551-v552, 2019
22019
Tumor Cell–Intrinsic p38 MAPK Signaling Promotes IL1α-Mediated Stromal Inflammation and Therapeutic Resistance in Pancreatic Cancer
SP Singh, AR Dosch, S Mehra, I De Castro Silva, A Bianchi, VT Garrido, ...
Cancer Research 84 (8), 1320-1332, 2024
12024
Surgical and oncologic outcomes with intraoperative radiation therapy for early breast cancer
O Friedman-Eldar, C Layton, I De Castro Silva, MG Moller, A Allen, ...
The American Surgeon™ 89 (4), 920-926, 2023
12023
Protective Effects of Urolithin A on Alcoholic Chronic Pancreatitis via Inhibiting PI3K/AKT/mTOR Signaling Pathway
S Mehra, S Srinivasan, X Dai, A Dosch, S Singh, A Bianchi, I Silva, ...
Pancreas 50 (7), 1082-1082, 2021
12021
P5. Impact Of Lymphatic Microsurgical Preventive Healing Approach (LYMPHA) On Postoperative Complication Rates In Immediate Prosthetic Based Breast Reconstruction: A …
A Desai, E Finkelstein, IDC Silva, M Clark, SB Kesmodel, KE Rojas, ...
Plastic and Reconstructive Surgery–Global Open 12 (S5), 41, 2024
2024
Patient Selection and Outcomes with Hepatic Artery Infusion Chemotherapy (HAIC) in Unresectable Colorectal Liver Metastasis (uCRLM) at a Tertiary Referral Center
EM Dickey, KL Koch, H Amirian, F Alessandrino, J Kronenfeld, IDC Silva, ...
ANNALS OF SURGICAL ONCOLOGY 31 (1), S204-S204, 2024
2024
Disrupting TNFR2 Signaling Improves Chemotherapy sensitivity in Pancreatic Cancer
H Amirian, Bianc-, Anna, I, K Rajkumar, A-am, Andrew, IDC Silva, ...
ANNALS OF SURGICAL ONCOLOGY 31 (1), S29-S29, 2024
2024
A novel mechanism of immunotherapy sensitivity following platinum chemotherapy resistance in pancreatic cancer patients with germline homologous recombination deficiency
I Ogobuiro, K Rajkumar, A Bianchi, L Caeiro, H Amirian, L Nivelo, ...
ANNALS OF SURGICAL ONCOLOGY 31 (1), S24-S25, 2024
2024
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