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Gary Lopaschuk
Gary Lopaschuk
Professor, Pediatrics, Universit of Alberta
Verified email at ualberta.ca
Title
Cited by
Cited by
Year
Myocardial substrate metabolism in the normal and failing heart
WC Stanley, FA Recchia, GD Lopaschuk
Physiological reviews 85 (3), 1093-1129, 2005
21892005
Myocardial fatty acid metabolism in health and disease
GD Lopaschuk, JR Ussher, CDL Folmes, JS Jaswal, WC Stanley
Physiological reviews 90 (1), 207-258, 2010
19362010
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
TR Koves, JR Ussher, RC Noland, D Slentz, M Mosedale, O Ilkayeva, ...
Cell metabolism 7 (1), 45-56, 2008
19042008
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
S Bonnet, SL Archer, J Allalunis-Turner, A Haromy, C Beaulieu, ...
Cancer cell 11 (1), 37-51, 2007
17302007
The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A …
PF Kantor, A Lucien, R Kozak, GD Lopaschuk
Circulation research 86 (5), 580-588, 2000
14252000
The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus
BN Finck, JJ Lehman, TC Leone, MJ Welch, MJ Bennett, A Kovacs, X Han, ...
The Journal of clinical investigation 109 (1), 121-130, 2002
11042002
Regulation of myocardial carbohydrate metabolism under normal and ischaemic conditions: potential for pharmacological interventions
WC Stanley, GD Lopaschuk, JL Hall, JG McCormack
Cardiovascular research 33 (2), 243-257, 1997
9051997
Regulation of fatty acid oxidation in the mammalian heart in health and disease
GD Lopaschuk, DD Belke, J Gamble, I Toshiyuki, BO Schönekess
Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism 1213 (3 …, 1994
7741994
High rates of fatty acid oxidation during reperfusion of ischemic hearts are associated with a decrease in malonyl-CoA levels due to an increase in 5’-AMP-activated protein …
N Kudo, AJ Barr, RL Barr, S Desai, GD Lopaschuk
Journal of Biological Chemistry 270 (29), 17513-17520, 1995
7211995
Cardiovascular remodelling in coronary artery disease and heart failure
G Heusch, P Libby, B Gersh, D Yellon, M Böhm, G Lopaschuk, L Opie
The Lancet 383 (9932), 1933-1943, 2014
7132014
Contribution of oxidative metabolism and glycolysis to ATP production in hypertrophied hearts
MF Allard, BO Schonekess, SL Henning, DR English, GD Lopaschuk
American Journal of Physiology-Heart and Circulatory Physiology 267 (2 …, 1994
6291994
Regulation of energy substrate metabolism in the diabetic heart
WC Stanley, GD Lopaschuk, JG McCormack
Cardiovascular research 34 (1), 25-33, 1997
6011997
Energy metabolic phenotype of the cardiomyocyte during development, differentiation, and postnatal maturation
GD Lopaschuk, JS Jaswal
Journal of cardiovascular pharmacology 56 (2), 130-140, 2010
5092010
Myocardial triglyceride turnover and contribution to energy substrate utilization in isolated working rat hearts
M Saddik, GD Lopaschuk
Journal of Biological Chemistry 266 (13), 8162-8170, 1991
4791991
AMPK alterations in cardiac physiology and pathology: enemy or ally?
JRB Dyck, GD Lopaschuk
The Journal of physiology 574 (1), 95-112, 2006
4562006
Acetyl-CoA carboxylase regulation of fatty acid oxidation in the heart.
M Saddik, J Gamble, LA Witters, GD Lopaschuk
Journal of Biological Chemistry 268 (34), 25836-25845, 1993
4351993
Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated …
ED Michelakis, MS McMurtry, XC Wu, JRB Dyck, R Moudgil, TA Hopkins, ...
Circulation 105 (2), 244-250, 2002
4152002
Targeting fatty acid and carbohydrate oxidation—a novel therapeutic intervention in the ischemic and failing heart
JS Jaswal, W Keung, W Wang, JR Ussher, GD Lopaschuk
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (7), 1333-1350, 2011
4052011
Pathways and control of ketone body metabolism: on the fringe of lipid biochemistry
T Fukao, GD Lopaschuk, GA Mitchell
Prostaglandins, leukotrienes and essential fatty acids 70 (3), 243-251, 2004
3962004
Ranolazine stimulates glucose oxidation in normoxic, ischemic, and reperfused ischemic rat hearts
JG McCormack, RL Barr, AA Wolff, GD Lopaschuk
Circulation 93 (1), 135-142, 1996
3741996
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