Mechanism of block and identification of the verapamil binding domain to HERG potassium channels S Zhang, Z Zhou, Q Gong, JC Makielski, CT January Circulation research 84 (9), 989-998, 1999 | 418 | 1999 |
Block of HERG potassium channels by the antihistamine astemizole and its metabolites desmethylastemizole and norastemizole Z Zhou, VR Vorperian, Q Gong, S Zhang, CT January Journal of cardiovascular electrophysiology 10 (6), 836-843, 1999 | 289 | 1999 |
Extracellular K+ concentration controls cell surface density of IKr in rabbit hearts and of the HERG channel in human cell lines J Guo, H Massaeli, J Xu, Z Jia, JT Wigle, N Mesaeli, S Zhang The Journal of clinical investigation 119 (9), 2745-2757, 2009 | 172 | 2009 |
Droperidol lengthens cardiac repolarization due to block of the rapid component of the delayed rectifier potassium current B Drolet, S Zhang, D Deschênes, J Rail, S Nadeau, Z Zhou, CT January, ... Journal of cardiovascular electrophysiology 10 (12), 1597-1604, 1999 | 141 | 1999 |
Identification of IKr and its trafficking disruption induced by probucol in cultured neonatal rat cardiomyocytes J Guo, H Massaeli, W Li, J Xu, T Luo, J Shaw, LA Kirshenbaum, S Zhang Journal of Pharmacology and Experimental Therapeutics 321 (3), 911-920, 2007 | 136 | 2007 |
The human ether-a-go-go-related gene (hERG) potassium channel represents an unusual target for protease-mediated damage SM Lamothe, J Guo, W Li, T Yang, S Zhang Journal of Biological Chemistry 291 (39), 20387-20401, 2016 | 111 | 2016 |
Cocaine blocks HERG, but not KvLQT1+ minK, potassium channels S Zhang, S Rajamani, Y Chen, Q Gong, Y Rong, Z Zhou, A Ruoho, ... Molecular pharmacology 59 (5), 1069-1076, 2001 | 94 | 2001 |
Cell surface expression of human ether-a-go-go-related gene (hERG) channels is regulated by caveolin-3 protein via the ubiquitin ligase Nedd4-2 J Guo, T Wang, X Li, H Shallow, T Yang, W Li, J Xu, MD Fridman, X Yang, ... Journal of Biological Chemistry 287 (40), 33132-33141, 2012 | 88 | 2012 |
Effect of preoperative obstructive sleep apnea on the frequency of atrial fibrillation after coronary artery bypass grafting EM van Oosten, A Hamilton, D Petsikas, D Payne, DP Redfearn, S Zhang, ... The American journal of cardiology 113 (6), 919-923, 2014 | 82 | 2014 |
Molecular determinants of the inhibition of human Kv1.5 potassium currents by external protons and Zn2+ SJ Kehl, C Eduljee, DCH Kwan, S Zhang, D Fedida The Journal of Physiology 541 (1), 9-24, 2002 | 78 | 2002 |
The serum-and glucocorticoid-inducible kinases SGK1 and SGK3 regulate hERG channel expression via ubiquitin ligase Nedd4-2 and GTPase Rab11 SM Lamothe, S Zhang Journal of Biological Chemistry 288 (21), 15075-15084, 2013 | 75 | 2013 |
Resveratrol prevents norepinephrine induced hypertrophy in adult rat cardiomyocytes, by activating NO-AMPK pathway SJ Thandapilly, XL Louis, T Yang, DM Stringer, L Yu, S Zhang, J Wigle, ... European journal of pharmacology 668 (1-2), 217-224, 2011 | 74 | 2011 |
Molecular determinants of cocaine block of human ether-a-go-go-related gene potassium channels J Guo, H Gang, S Zhang Journal of Pharmacology and Experimental Therapeutics 317 (2), 865-874, 2006 | 68 | 2006 |
Effects ofα1-adrenergic Stimulation on L-type Ca2+ Current in Rat Ventricular Myocytes S Zhang, M Hiraoka, Y Hirano Journal of molecular and cellular cardiology 30 (10), 1955-1965, 1998 | 59 | 1998 |
Extracellular K+ Is a Prerequisite for the Function and Plasma Membrane Stability of HERG Channels H Massaeli, J Guo, J Xu, S Zhang Circulation research 106 (6), 1072-1082, 2010 | 57 | 2010 |
Isolation and characterization of IKr in cardiac myocytes by Cs+ permeation S Zhang American Journal of Physiology-Heart and Circulatory Physiology 290 (3 …, 2006 | 54 | 2006 |
Reduced hemodynamic load aids low-dose resveratrol in reversing cardiovascular defects in hypertensive rats SJ Thandapilly, XL Louis, J Behbahani, A Movahed, L Yu, R Fandrich, ... Hypertension Research 36 (10), 866-872, 2013 | 53 | 2013 |
Interaction between the cardiac rapidly (IKr) and slowly (IKs) activating delayed rectifier potassium channels revealed by low K+-induced hERG endocytic degradation J Guo, T Wang, T Yang, J Xu, W Li, MD Fridman, JT Fisher, S Zhang Journal of Biological Chemistry 286 (40), 34664-34674, 2011 | 52 | 2011 |
Involvement of caveolin in probucol-induced reduction in hERG plasma-membrane expression J Guo, X Li, H Shallow, J Xu, T Yang, H Massaeli, W Li, T Sun, GN Pierce, ... Molecular Pharmacology 79 (5), 806-813, 2011 | 49 | 2011 |
Calcium‐dependent Nedd4‐2 upregulation mediates degradation of the cardiac sodium channel Nav1. 5: implications for heart failure L Luo, F Ning, Y Du, B Song, D Yang, SC Salvage, Y Wang, JA Fraser, ... Acta Physiologica 221 (1), 44-58, 2017 | 48 | 2017 |