Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia H Kuusanmäki, O Dufva, M Vähä-Koskela, AM Leppä, J Huuhtanen, ... Blood 141 (13), 1610-1625, 2023 | 33 | 2023 |
Single-cell functional genomics reveals determinants of sensitivity and resistance to natural killer cells in blood cancers O Dufva, S Gandolfi, J Huuhtanen, O Dashevsky, H Duàn, K Saeed, ... Immunity 56 (12), 2816-2835. e13, 2023 | 8 | 2023 |
Single-cell functional genomics of natural killer cell evasion in blood cancers O Dufva, S Gandolfi, J Huuhtanen, O Dashevsky, K Saeed, J Klievink, ... bioRxiv, 2022.08. 22.504722, 2022 | 3 | 2022 |
Single-cell analysis of immune recognition in chronic myeloid leukemia patients following tyrosine kinase inhibitor discontinuation J Huuhtanen, S Adnan-Awad, J Theodoropoulos, S Forstén, R Warfvinge, ... Leukemia 38 (1), 109-125, 2024 | 2 | 2024 |
Single-Cell Functional Genomics of Natural Killer Cell Interaction with Blood Cancers O Dufva, S Gandolfi, J Huuhtanen, O Dashevsky, K Saeed, J Klievink, ... Blood 140 (Supplement 1), 8343-8344, 2022 | 1 | 2022 |
Functional genomic landscape of natural killer cell evasion in multiple myeloma S Gandolfi, O Dufva, J Huuhtanen, O Dashevsky, J Klievink, J Bouhlal, ... Blood 138, 732, 2021 | 1 | 2021 |
OAB-019: CRISPR screens with single-cell transcriptome readout reveal potential mechanisms of response to natural killer cell treatment in multiple myeloma S Gandolfi, O Dufva, J Huuhtanen, O Dashevsky, J Klievink, J Bouhlal, ... Clinical Lymphoma Myeloma and Leukemia 21, S12-S13, 2021 | 1 | 2021 |
Primary Acute Myeloid Leukemia Cells Trigger Distinct Activation Patterns in Expanded NK Cells H Duàn, O Dufva, E Jokinen, H Lähteenmäki, J Klievink, J Bouhlal, ... Blood 142, 66, 2023 | | 2023 |
High-Throughput Screens Identify NEDD8 Inhibition As a Strategy to Augment Natural Killer Cell Cytotoxicity Against Blood Cancers J Bouhlal, P Nygren, E Jokinen, E Laajala, A Ianevski, D Dias, J Klievink, ... Blood 142, 3634, 2023 | | 2023 |
Single-cell functional genomics of natural killer cell evasion by tumor cells O Dufva, S Gandolfi, J Huuhtanen, O Dashevsky, K Saeed, J Klievink, ... Cancer Research 83 (7_Supplement), 667-667, 2023 | | 2023 |
High-throughput screening and single-cell transcriptomics identify synergies between oncology drugs and natural killer cell immunotherapy JO Bouhlal, P Nygren, E Laajala, A Ianevski, J Klievink, H Lähteenmäki, ... Cancer Research 83 (7_Supplement), 2912-2912, 2023 | | 2023 |
Erythroid/Megakaryocytic Differentiation Confers BCL-XL Dependency and Venetoclax Resistance in Acute Myeloid Leukemia O Dufva, H Kuusanmäki, M Vaha-Koskela, AM Leppä, J Huuhtanen, ... Blood 140 (Supplement 1), 101-103, 2022 | | 2022 |
S151: HIGH-THROUGHPUT EVALUATION OF THE POTENTIAL OF CANCER DRUGS TO ENHANCE NATURAL KILLER CELL IMMUNOTHERAPY IN CHRONIC MYELOID LEUKEMIA. P Nygren, J Bouhlal, E Laajala, A Ianevski, J Klievink, H Lähteenmäki, ... HemaSphere 6, 52-53, 2022 | | 2022 |
High-throughput evaluation of the combinatorial approach to improve NK cell JOV Bouhlal Identity 2 (1), 0, 2022 | | 2022 |
High-throughput evaluation of the combinatorial approach to improve NK cell immunotherapy using anti-cancer drugs in acute myeloid leukaemia JOV Bouhlal Helsingin yliopisto, 2022 | | 2022 |