Intestinal HIF-1α deletion exacerbates alcoholic liver disease by inducing intestinal dysbiosis and barrier dysfunction T Shao, C Zhao, F Li, Z Gu, L Liu, L Zhang, Y Wang, L He, Y Liu, Q Liu, ... Journal of hepatology 69 (4), 886-895, 2018 | 187 | 2018 |
Following spinal cord injury, PDE4B drives an acute, local inflammatory response and a chronic, systemic response exacerbated by gut dysbiosis and endotoxemia SA Myers, L Gobejishvili, SS Ohri, CG Wilson, KR Andres, AS Riegler, ... Neurobiology of disease 124, 353-363, 2019 | 71 | 2019 |
Decrease in acetyl-CoA pathway utilizing butyrate-producing bacteria is a key pathogenic feature of alcohol-induced functional gut microbial dysbiosis and development of liver … R Singhal, H Donde, S Ghare, K Stocke, J Zhang, M Vadhanam, S Reddy, ... Gut microbes 13 (1), 1946367, 2021 | 36 | 2021 |
Tributyrin inhibits ethanol-induced epigenetic repression of CPT-1A and attenuates hepatic steatosis and injury H Donde, S Ghare, S Joshi-Barve, JW Zhang, MV Vadhanam, ... Cellular and Molecular Gastroenterology and Hepatology 9 (4), 569-585, 2020 | 33 | 2020 |
Acrolein enhances epigenetic modifications, FasL expression and hepatocyte toxicity induced by anti-HIV drug Zidovudine SS Ghare, H Donde, WY Chen, DF Barker, L Gobejishvilli, CJ McClain, ... Toxicology in Vitro 35, 66-76, 2016 | 8 | 2016 |
Role of ethanol as a cofactor in HAART induced hepatic steatosis and injury. H Donde | 1 | 2013 |
DECREASE IN ACETYL-CoA PATHWAY UTILIZING BUTYRATE-PRODUCING BACTERIA IS A KEY PATHOGENIC FEATURE OF ALCOHOL-INDUCED GUT MICROBIAL DYSBIOSIS AND DEVELOPMENT OF LIVER DISEASE IN MICE R Singhal, H Donde, S Ghare, K Stocke, J Zhang, M Vadhanam, S Reddy, ... HEPATOLOGY 74, 355A-355A, 2021 | | 2021 |
LOSS OF BUTYRATE PRODUCING BACTERIA IS A SIGNIFICANT FEATURE OF ALCOHOL-INDUCED GUT MICROBIAL DYSBIOSIS AND PATHOGENESIS OF ALCOHOLIC LIVER DISEASE R Singhal, H Donde, K Stocke, M Vital, S Ghare, S Reddy, L Gobejishvili, ... ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 44, 46-46, 2020 | | 2020 |
Tributyrin Targets the Gut Microbial Dysbiosis and Pathogenic Epigenetic Mechanisms in the Liver in an Animal Model of ALD H Donde, R Singhal, S Ghare, J Zhang, S Joshi-Barve, CJ McClain, ... HEPATOLOGY 68, 218A-218A, 2018 | | 2018 |
TRIBUTYRIN ATTENUATES ALCOHOL-INDUCED CHEMOKINE UP-REGULATION VIA EPIGENETIC MECHANISMS: RELEVANCE TO HEPATIC INFLAMMATION AND INJURY IN ALD S Ghare, H Donde, BT Charpentier, MV Vadhanam, S Joshi-Barve, ... ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 42, 54A-54A, 2018 | | 2018 |
ORAL ADMINISTRATION OF TRIBUTYRIN SIGNIFICANTLY ATTENUATES ALCOHOL INDUCED NEUROINFLAMMATION B Charpentier, H Donde, MV Vadhanam, SA Myers, S Joshi-Barve, ... ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 42, 161A-161A, 2018 | | 2018 |
Tributyrin Administration Targets Alcohol‐induced Pathogenic Mechanisms in the Gut‐liver Axis: Relevance to the Development of Therapeutic Strategies in Alcoholic Liver Disease HM Donde, G Wilson, S Ghare, JW Zhang, M Vadhanam, S Joshi‐Barve, ... The FASEB Journal 32, 563.12-563.12, 2018 | | 2018 |
Tributyrin supplementation attenuates alcohol induced dysbiosis and liver injury H Donde, S Ghare, C Wilson, C Gail, L Negy, L Gobejishvili, ... The FASEB Journal 31, 994.9-994.9, 2017 | | 2017 |
ORAL ADMINISTRATION OF TRIBUTYRIN DECREASES ALCOHOL INDUCED HEPATIC EXPRESSION OF CCL-2 AND CXCL-2 AND ATTENUATES NEUTROPHIL INFILTRATION AND INJURY H Donde, S Ghare, J Zhang, S Joshi-Barve, CJ McClain, S Barve ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 40, 31A-31A, 2016 | | 2016 |
Tributyrin, a butyrate pro-drug, attenuates alcohol-induced inflammation and neutrophil-mediated hepatic injury H Donde, S Ghare, J Zhang, S Joshi-Barve, CJ McClain, S Barve HEPATOLOGY 62, 864A-864A, 2015 | | 2015 |
ORAL ADMINISTRATION OF TRIBUTYRIN TARGETS THE" GUT-LIVER" AXIS AND ATTENUATES ALCOHOLIC LIVER DISEASE (ALD) H Donde, S Ghare, GA Cresci, LE Nagy, J Zhang, L Gobejishvili, ... ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 39, 169A-169A, 2015 | | 2015 |
Mechanistic role of PDE4/cAMP in the development of HIV‐PI induced FasL mediated hepatotoxicity H Donde, S Ghare, D Barker, S Joshi‐Barve, S Barve, C McClain The FASEB Journal 29, 937.6, 2015 | | 2015 |
Acrolein Exacerbates HAART–Induced Apoptotic Death in Hepatocytes by Enhancing Transcriptionally Permissive Epigenetic Modifications at FasL Promoter S Ghare, H Donde, S Joshi‐Barve, C McClain, S Barve The FASEB Journal 29, 569.11, 2015 | | 2015 |
Mechanisms and intervention strategies for alcohol and HIV-antiretroviral therapy-induced liver injury. H Donde | | 2015 |
Oral Administration of Tributyrin Attenuates Chronic Ethanol-Induced Hepatic Steatosis, Inflammation and Injury: 1144 H Donde, J Zhang, S Ghare, L Gobejishvili, S Joshi-Barve, V Vatsalya, ... Hepatology 60, 755A, 2014 | | 2014 |