| Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1 DA Barbie, P Tamayo, JS Boehm, SY Kim, SE Moody, IF Dunn, ... Nature 462 (7269), 108-112, 2009 | 2522 | 2009 |
| Defining T cell states associated with response to checkpoint immunotherapy in melanoma M Sade-Feldman, K Yizhak, SL Bjorgaard, JP Ray, CG de Boer, ... Cell 175 (4), 998-1013. e20, 2018 | 1050 | 2018 |
| Mechanisms of resistance to immune checkpoint inhibitors RW Jenkins, DA Barbie, KT Flaherty British journal of cancer 118 (1), 9-16, 2018 | 935 | 2018 |
| A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ... Cell 175 (4), 984-997. e24, 2018 | 777 | 2018 |
| Synthetic Lethal Interaction between Oncogenic KRAS Dependency and STK33 Suppression in Human Cancer Cells C Scholl, S Fröhling, IF Dunn, AC Schinzel, DA Barbie, SY Kim, SJ Silver, ... Cell 137 (5), 821-834, 2009 | 611 | 2009 |
| Highly parallel identification of essential genes in cancer cells B Luo, HW Cheung, A Subramanian, T Sharifnia, M Okamoto, X Yang, ... Proceedings of the National Academy of Sciences 105 (51), 20380-20385, 2008 | 607 | 2008 |
| AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer KM Vasudevan, DA Barbie, MA Davies, R Rabinovsky, CJ McNear, ... Cancer cell 16 (1), 21-32, 2009 | 584 | 2009 |
| Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine EM Van Allen, N Wagle, P Stojanov, DL Perrin, K Cibulskis, S Marlow, ... Nature medicine 20 (6), 682-688, 2014 | 527 | 2014 |
| CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell ActivationCDK4/6 Inhibition Enhances the Antitumor T-cell Response J Deng, ES Wang, RW Jenkins, S Li, R Dries, K Yates, S Chhabra, ... Cancer discovery 8 (2), 216-233, 2018 | 461 | 2018 |
| NPAT links cyclin E–Cdk2 to the regulation of replication-dependent histone gene transcription J Zhao, BK Kennedy, BD Lawrence, DA Barbie, AG Matera, JA Fletcher, ... Genes & development 14 (18), 2283-2297, 2000 | 432 | 2000 |
| STK11/LKB1 deficiency promotes neutrophil recruitment and proinflammatory cytokine production to suppress T-cell activity in the lung tumor MicroenvironmentImmunosuppressive … S Koyama, EA Akbay, YY Li, AR Aref, F Skoulidis, GS Herter-Sprie, ... Cancer research 76 (5), 999-1008, 2016 | 431 | 2016 |
| Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitor CL Christensen, N Kwiatkowski, BJ Abraham, J Carretero, F Al-Shahrour, ... Cancer cell 26 (6), 909-922, 2014 | 395 | 2014 |
| Genomic correlates of response to immune checkpoint blockade in microsatellite-stable solid tumors D Miao, CA Margolis, NI Vokes, D Liu, A Taylor-Weiner, SM Wankowicz, ... Nature genetics 50 (9), 1271-1281, 2018 | 392 | 2018 |
| Nuclear organization of DNA replication in primary mammalian cells BK Kennedy, DA Barbie, M Classon, N Dyson, E Harlow Genes & development 14 (22), 2855-2868, 2000 | 385 | 2000 |
| Ex vivo profiling of PD-1 blockade using organotypic tumor SpheroidsEx vivo profiling of immune checkpoint blockade RW Jenkins, AR Aref, PH Lizotte, E Ivanova, S Stinson, CW Zhou, ... Cancer discovery 8 (2), 196-215, 2018 | 343 | 2018 |
| Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent VV Ogryzko, TH Hirai, VR Russanova, DA Barbie, BH Howard Molecular and cellular biology 16 (9), 5210-5218, 1996 | 329 | 1996 |
| A-type lamins regulate retinoblastoma protein function by promoting subnuclear localization and preventing proteasomal degradation BR Johnson, RT Nitta, RL Frock, L Mounkes, DA Barbie, CL Stewart, ... Proceedings of the National Academy of Sciences 101 (26), 9677-9682, 2004 | 304 | 2004 |
| Suppression of STING Associated with LKB1 Loss in KRAS-Driven Lung CancerSilencing of STING in KRAS-LKB1–Mutant Lung Cancer S Kitajima, E Ivanova, S Guo, R Yoshida, M Campisi, SK Sundararaman, ... Cancer discovery 9 (1), 34-45, 2019 | 245 | 2019 |
| RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth … A Lai, BK Kennedy, DA Barbie, NR Bertos, XJ Yang, MC Theberge, ... Molecular and cellular biology 21 (8), 2918-2932, 2001 | 238 | 2001 |
| Treatment-induced tumor dormancy through YAP-mediated transcriptional reprogramming of the apoptotic pathway KJ Kurppa, Y Liu, C To, T Zhang, M Fan, A Vajdi, EH Knelson, Y Xie, ... Cancer cell 37 (1), 104-122. e12, 2020 | 223 | 2020 |
