| Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19 C Mirabelli, JW Wotring, CJ Zhang, SM McCarty, R Fursmidt, CD Pretto, ... Proceedings of the National Academy of Sciences 118 (36), e2105815118, 2021 | 198 | 2021 |
| SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation B Yan, T Freiwald, D Chauss, L Wang, E West, C Mirabelli, CJ Zhang, ... Science immunology 6 (58), eabg0833, 2021 | 155 | 2021 |
| A human liver organoid screening platform for DILI risk prediction CJ Zhang, SR Meyer, MJ O’Meara, S Huang, MM Capeling, ... Journal of hepatology 78 (5), 998-1006, 2023 | 38 | 2023 |
| Virtual screening and experimental testing of B1 metallo-β-lactamase inhibitors JS Kang, AL Zhang, M Faheem, CJ Zhang, N Ai, JD Buynak, WJ Welsh, ... Journal of chemical information and modeling 58 (9), 1902-1914, 2018 | 30 | 2018 |
| EPIREGULIN creates a developmental niche for spatially organized human intestinal enteroids CJ Childs, EM Holloway, CW Sweet, YH Tsai, A Wu, A Vallie, MK Eiken, ... JCI insight 8 (6), 2023 | 5 | 2023 |
| Mapping the adult human esophagus in vivo and in vitro D Ferrer-Torres, JH Wu, CJ Zhang, MA Hammer, MK Dame, A Wu, ... Development 149 (20), dev200614, 2022 | 5 | 2022 |
| SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation. Sci Immunol 6: eabg0833 B Yan, T Freiwald, D Chauss, L Wang, E West, C Mirabelli, CJ Zhang, ... | 5 | 2021 |
| Mutation S115T in IMP-type metallo-β-lactamases compensates for decreased expression levels caused by mutation S119G CJ Zhang, M Faheem, P Dang, MN Morris, P Kumar, P Oelschlaeger Biomolecules 9 (11), 724, 2019 | 5 | 2019 |
| Antisense oligonucleotides to therapeutically target SARS-CoV-2 infection Y Qiao, JW Wotring, CJ Zhang, X Jiang, L Xiao, A Watt, D Gattis, ... PloS one 18 (2), e0281281, 2023 | 4 | 2023 |
| Role of synonymous mutations in the evolution of TEM β-lactamase genes M Faheem, CJ Zhang, MN Morris, J Pleiss, P Oelschlaeger Antimicrobial Agents and Chemotherapy 65 (6), 10.1128/aac. 00018-21, 2021 | 4 | 2021 |
| A multi-omics human liver organoid screening platform for DILI risk prediction CJ Zhang, MJ O’Meara, SR Meyer, S Huang, MM Capeling, ... bioRxiv, 457824, 2021 | 3 | 2021 |
| Opposing roles for TGFβ-and BMP-signaling during nascent alveolar differentiation in the developing human lung T Frum, PP Hsu, RFC Hein, AS Conchola, CJ Zhang, OR Utter, A Anand, ... NPJ Regenerative Medicine 8 (1), 48, 2023 | 2 | 2023 |
| In Vitro Evaluation and Mitigation of Niclosamide’s Liabilities as a COVID-19 Treatment JW Wotring, SM McCarty, K Shafiq, CJ Zhang, T Nguyen, SR Meyer, ... Vaccines 10 (8), 1284, 2022 | 2 | 2022 |
| Proxalutamide reduces SARS-CoV-2 infection and associated inflammatory response Y Qiao, JW Wotring, Y Zheng, CJ Zhang, Y Zhang, X Jiang, CD Pretto, ... Proceedings of the National Academy of Sciences 120 (30), e2221809120, 2023 | 1 | 2023 |
| Type I interferon signaling induces a delayed antiproliferative response in respiratory epithelial cells during SARS-CoV-2 infection J Bragazzi Cunha, K Leix, EJ Sherman, C Mirabelli, T Frum, CJ Zhang, ... Journal of Virology 97 (12), e01276-23, 2023 | | 2023 |
| DRUG-INDUCED PERTURBATIONS OF NONPARENCHYMAL STELLATE CELLS IN HUMAN LIVER ORGANOIDS USING CELL PAINTING AND SINGLECELL RNA SEQUENCING S Meyer, C Zhang, RJ Fontana, J Sexton HEPATOLOGY 78, S1519-S1520, 2023 | | 2023 |
| A HIGH THROUGHPUT AUTOMATABLE MICROFLUIDIC LIVER ORGANOID CHIP FOR LONG-TERM DILI MODELLING C Zhang, S Kim, S Meyer, A Jolly, B Lee, J Kim, S Yoo, TL Liu, K Baek, ... HEPATOLOGY 78, S2145-S2145, 2023 | | 2023 |
| DIFFERENTIAL DRUG RESPONSES AMONGST 4 IDIOSYNCRATIC DRUG-INDUCED LIVER INJURY PATIENT-DERIVED HUMAN LIVER ORGANOIDS C Zhang, S Meyer, M Garcia, M Procario, A Tucker, RJ Fontana, J Sexton HEPATOLOGY 78, S2144-S2144, 2023 | | 2023 |
| A High-Throughput Microphysiological Liver Chip System to Model Direct and Idiosyncratic Drug-Induced Liver Injury Using Human Liver Organoids CJ Zhang, SR Meyer, MA Garcia, MC Procario, S Yoo, AL Jolly, S Kim, ... bioRxiv, 2023.12. 01.569575, 2023 | | 2023 |
| HUMAN LIVER ORGANOIDS CAN HELP IDENTIFY HEPATOTOXIC INGREDIENTS IN HERBAL AND DIETARY SUPPLEMENTS ASSOCIATED WITH CLINICALLY SIGNIFICANT LIVER INJURY C Zhang, K Shafiq, SR Meyer, I Khan, VJ Navarro, RD Kersten, ... HEPATOLOGY 76, S1441-S1442, 2022 | | 2022 |
