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Antje Rottner
Antje Rottner
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
Loss of ZnT8 function protects against diabetes by enhanced insulin secretion
OP Dwivedi, M Lehtovirta, B Hastoy, V Chandra, NAJ Krentz, S Kleiner, ...
Nature genetics 51 (11), 1596-1606, 2019
1252019
Prioritising causal genes at type 2 diabetes risk loci
AK Grotz, AL Gloyn, SK Thomsen
Current diabetes reports 17, 1-9, 2017
412017
A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk
AK Rottner, Y Ye, E Navarro-Guerrero, V Rajesh, A Pollner, RJ Bevacqua, ...
Nature Genetics 55 (1), 54-65, 2023
32*2023
A CRISPR/Cas9 genome editing pipeline in the EndoC-βH1 cell line to study genes implicated in beta cell function [version 1; peer review: 2 approved,
A Grotz, F Abaitua, E Navarro-Guerrero, B Hastoy, D Ebner, A Gloyn
Wellcome Open Research 4 (150), 2019
262019
Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression
KK Mattis, NAJ Krentz, C Metzendorf, F Abaitua, AF Spigelman, H Sun, ...
Diabetologia, 1-21, 2023
92023
A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo
B Bestas, S Wimberger, D Degtev, A Madsen, AK Rottner, F Karlsson, ...
Nature Communications 14 (1), 5474, 2023
62023
Systemic gene therapy with thymosin b4 alleviates glomerular injury in mice
WJ Mason, DJ Jafree, G Pomeranz, M Kolatsi-Joannou, AK Rottner, ...
Nature Research, 0
4
3-LB: The Type 2 Diabetes-Associated Transcription Factor RREB1 Affects Beta-Cell Function and Development
KK Mattis, F Abaitua, A Grotz, A Wesolowska-Andersen, ...
Diabetes 68 (Supplement 1), 2019
22019
Pooled CRISPR KO screens for target identification
A Grotz, S Deswal
Genome Editing in Drug Discovery, 113-125, 2022
12022
From 61 Type-2 diabetes genes to 2: Three in vivo perturbation screening steps highlight sirt1 and poldip2 as T2D genes
E Mujica, H Zhang, A Emmanouilidou, N Cook, C Metzendorf, ...
2024
220-LB: Characterizing the Role of 99 Cardiometabolic Candidate Genes Using CRISPR/Cas9, In Vivo Imaging, and Deep Learning in Zebrafish Larvae
E MUJICA, H ZHANG, A EMMANOUILIDOU, E MAZZAFERRO, N COOK, ...
Diabetes 72 (Supplement_1), 2023
2023
2050-P: A Multiomics Investigation of a Patient-Derived HNF-1A MODY IPSC Disease Model Reveals Insights into Its Role in Pancreatic Islet Development and Function
C Duff, RR Jensen, M Perez-Alcantara, M Rasmussen, A Grotz, M Jansen, ...
Diabetes 69 (Supplement_1), 2020
2020
Identifying genes involved in beta cell dysfunction using high-throughput genetic and genomic approaches
AK Grotz
University of Oxford, 2020
2020
3-LB: The Type 2 Diabetes-Associated Transcription Factor RREB1 Affects Beta-Cell Function and Development
KK Mattis, F Abaitua, A Grotz, A Wesolowska-Andersen, ...
Diabetes 68 (Supplement 1), 2019
2019
25-OR: Investigating a Candidate Causal Allele in Type 2 Diabetes Susceptibility Gene PAM as a Cause of Neonatal Diabetes Mellitus
S Sengupta, LL Bonnycastle, B Hastoy, A Grotz, MM Umapathysivam, ...
Diabetes 68 (Supplement_1), 2019
2019
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